Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jason Schofield"'
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 123
Autor:
Matthew Skinner, Shaodong Wang, Debbie Adkins, Stefan Platz, Jason Schofield, Li Zhao, Weijun Zheng, Hong Yu, Guozhen Xing, Miaomiao Hu, Karen Oldman, Jin Ren, Jing Lu
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 75:44-51
Introduction Assessing the cardiovascular safety of new chemical or biological entities is important during pre-clinical development. Electrocardiogram (ECG) assessments in non-human primate (NHP) toxicology studies are often made using non-invasive
Autor:
Stevan Hunter, Jason Schofield, Steven Sheffield, Troy Ruud, Kyle Wilkins, Bryce Rasmussen, Cesar Salas, Marco Salas, Jose Martinez, Vail McBride
Publikováno v:
IEEE Transactions on Components, Packaging and Manufacturing Technology. 3:880-887
IC pad damage from a wafer probe can be detrimental to wire-bond yield and product reliability. In this paper, bond pads are harshly probed on traditional pads and a variety of experimental circuit-under-pad (CUP) structures in technologies having al
Autor:
Marco Salas, Kyle Wilkins, Stevan Hunter, Cesar Salas, Jose Martinez, Jason Schofield, Steven Sheffield
Publikováno v:
International Symposium on Microelectronics. 2011:000491-000501
IC bond pad structural reliability is studied for a variety of experimental pad designs in a 0.18um technology, having patterned metallization to simulate bond-over-active-circuitry (BOAC) situations in top-metal-minus-one and below. Underlying films
Autor:
Jason Schofield, Troy Ruud, Cesar Salas, Bryce Rasmussen, Marco Salas, Jim Workman, Kyle Wilkins, Jose Martinez, Steven Sheffield, Stevan Hunter
Publikováno v:
International Symposium on Microelectronics. 2011:000249-000257
This paper discusses layout design rules for successful Cu wire bond-over-active-circuitry (BOAC) in 0.18 micron and other IC technologies having Al metallization interconnects (two-level metal and up) in SiO2 dielectric, with W vias. The resulting b
Publikováno v:
Toxicologic pathology. 41(5)
We evaluated immunohistochemistry (von Willebrand Factor [vWF] or fibrinogen) and systemic and coronary arterial physiological parameters in beagle dogs to investigate early arterial lesions induced by the potassium channel opener, ZD6169, or the end
Publikováno v:
Journal of pharmacological and toxicological methods. 60(2)
Introduction The primary objective of this investigation was to evaluate the sensitivity of a non-invasive telemetry system for the detection of drug-induced electrocardiogram (ECG) changes in conscious, freely moving dogs. A secondary objective was
Autor:
Jean-Pierre Valentin, Helen Prior, Jason Schofield, S Bjurstrom, G Evans, Linda Foster-Brown, K Kenne, Rudy J. Richardson, Anne M. Katein, Ina Schuppe-Koistinen, H. Jones, David Brott, Graham Betton, Calvert Louden, Sarah Gould
Publikováno v:
Toxicology and applied pharmacology. 207
In pre-clinical safety studies, drug-induced vascular injury is an issue of concern because there are no obvious diagnostic markers for pre-clinical or clinical monitoring and there is an intellectual gap in our understanding of the pathogenesis of t
Publikováno v:
Toxicology Letters. 205:S204-S205
Autor:
Helen Prior, Jean-Pierre Valentin, Matthew Skinner, Jason Schofield, Claire Grant, Pierre Lainee
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 66:176