Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jason S. Silverman"'
Publikováno v:
Traffic. 14:1078-1090
The multivesicular body (MVB) is a specialized Rab7+ late endosome (LE) containing multiple intralumenal vesicles that function in targeting ubiquitinylated cell surface proteins to the lysosome for degradation. African trypanosomes lack a morphologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d1516415ddf65ba7b61e3cdbf8b5b5e
https://doi.org/10.1111/tra.12094
https://doi.org/10.1111/tra.12094
Autor:
Kevin J. Schwartz, Jason S. Silverman, Elitza S. Sevova, James D. Bangs, Shaheen S. Sutterwala, Ngii N. Tazeh
Publikováno v:
Eukaryotic Cell. 8:1352-1361
African trypanosomes are the causative agents of human trypanosomiasis (sleeping sickness). The pathogenic stage of the parasite has unique adaptations to life in the bloodstream of the mammalian host, including upregulation of endocytic and lysosoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896d40e6c0c742718095fa04499a2d47
https://doi.org/10.1128/ec.00156-09
https://doi.org/10.1128/ec.00156-09
Autor:
Nathan W. Rigel, Jason S. Silverman, Erin McElvania TeKippe, Justin A. McDonough, Miriam Braunstein, Jessica R. McCann
Publikováno v:
Journal of Bacteriology. 190:6428-6438
The twin-arginine translocation (Tat) pathway is a system used by some bacteria to export proteins out from the cytosol to the cell surface or extracellular environment. A functional Tat pathway exists in the important human pathogen Mycobacterium tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9372dbfd239c48f74f7aeab61eb848e0
https://doi.org/10.1128/jb.00749-08
https://doi.org/10.1128/jb.00749-08
Autor:
Jason S. Silverman, James D. Bangs
Publikováno v:
Current opinion in microbiology. 15(4)
Recent advances in secretory biology of African trypanosomes reveal both similarities and striking differences with other model eukaryotic organisms. Secretion is streamlined for rapid and selective transport of the major cargo, VSG. Selectivity in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97986d103c9b743293570f5db65f1aaf
https://pubmed.ncbi.nlm.nih.gov/22445359
https://pubmed.ncbi.nlm.nih.gov/22445359
Publikováno v:
Molecular microbiology. 82(3)
We present the first functional analysis of the small GTPase, TbRab7, in Trypanosoma brucei. TbRab7 defines discrete late endosomes closely juxtaposed to the terminal p67(+) lysosome. RNAi indicates that TbRab7 is essential in bloodstream trypanosome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b25fa7bc28903b32cf016e4e83b4f4d6
https://pubmed.ncbi.nlm.nih.gov/21923766
https://pubmed.ncbi.nlm.nih.gov/21923766