Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Jason S Ellis"'
Autor:
Fatemeh Fattahi, Jason S Ellis, Michael Sylvester, Kristin Bahleda, Njira L Lugogo, Ulus Atasoy
Publikováno v:
The Journal of Immunology. 208:166.09-166.09
The RNA-binding protein HuR (elavl1) positively regulates the expression of its targets by increasing mRNA stability and translation. Th2 and Th17 related genes play critical roles in airway inflammation in both mouse and human. Using in vitro and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::914560c2293135d8a04339adb8ea4564
https://doi.org/10.4049/jimmunol.208.supp.166.09
https://doi.org/10.4049/jimmunol.208.supp.166.09
Publikováno v:
The Journal of Immunology. 208:44.11-44.11
The RNA-binding protein HuR (Elavl1) plays a critical role in T cell activation and function by regulating the stability and transport of its mRNA targets. To study the role of HuR in regulatory T cell (Treg) development and function, we generated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2a60e5884d9d7dd610149aaf08362c0
https://doi.org/10.4049/jimmunol.208.supp.44.11
https://doi.org/10.4049/jimmunol.208.supp.44.11
Autor:
Myriam Gorospe, Suzanne E. Ridenhour, Hao Zhou, Wade Davis, Patsharaporn Techasintana, Ulus Atasoy, Joseph D. Magee, Xiaoxia Li, Marcia L. Hart, Jason S. Ellis, Paul L. Fox, Peng Yao, Maryln S. Whitney, Craig L. Franklin, Jennifer L. Martindale, Jacqueline J. Glascock, Matthew M. Gubin
Publikováno v:
ImmunoHorizons. 1:109-123
Posttranscriptional gene regulation by RNA-binding proteins, such as HuR (elavl1), fine-tune gene expression in T cells, leading to powerful effects on immune responses. HuR can stabilize target mRNAs and/or promote translation by interacting with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::676eb12302c8bc8e7a3a6e6e7505971b
https://doi.org/10.4049/immunohorizons.1700017
https://doi.org/10.4049/immunohorizons.1700017
Autor:
Fatemeh Fattahi, Jason S Ellis, Michael Sylvester, Kristin Bahelda, Sam Hietanen, Luis O Correa, Njira Lugogo, Ulus Atasoy
Publikováno v:
The Journal of Immunology. 206:53.12-53.12
RNA-binding protein human antigen R (HuR) is a master regulator of gene expression in human pathophysiology. Our animal studies in the past showed multiple critical roles for HuR in regulating proinflammatory markers in CD4+ T cells. We hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92c19cae03c515ed38a9284cbb73d4f6
https://doi.org/10.4049/jimmunol.206.supp.53.12
https://doi.org/10.4049/jimmunol.206.supp.53.12
Publikováno v:
The Journal of Immunology. 206:12.18-12.18
The RNA binding protein HuR (elavl1) stabilizes target mRNAs and aids in their transport to the heavy polysomes, ultimately resulting in increased protein expression. We have previously shown that HuR plays a critical role in T helper cell fate decis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7cacde607d29dcaa8d88bdde3bbc56c
https://doi.org/10.4049/jimmunol.206.supp.12.18
https://doi.org/10.4049/jimmunol.206.supp.12.18
Publikováno v:
Immunology. 147:464-475
Effective humoral immunity ensues when antigen presentation by B cells culminates in productive cooperation with T lymphocytes. This collaboration, however, remains ill-defined because naive antigen-specific B cells are rare and difficult to track in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1496da54f5cd5fc6b0fd3248cc33803
https://doi.org/10.1111/imm.12579
https://doi.org/10.1111/imm.12579
Autor:
Patsharaporn, Techasintana, Jason S, Ellis, Jacqueline, Glascock, Matthew M, Gubin, Suzanne E, Ridenhour, Joseph D, Magee, Marcia L, Hart, Peng, Yao, Hao, Zhou, Maryln S, Whitney, Craig L, Franklin, Jennifer L, Martindale, Myriam, Gorospe, Wade J, Davis, Paul L, Fox, Xiaoxia, Li, Ulus, Atasoy
Publikováno v:
ImmunoHorizons
Posttranscriptional gene regulation by RNA-binding proteins, such as HuR (elavl1), fine-tune gene expression in T cells, leading to powerful effects on immune responses. HuR can stabilize target mRNAs and/or promote translation by interacting with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6a23b85395f2bdc84728a42745a3967
https://pubmed.ncbi.nlm.nih.gov/30035254
https://pubmed.ncbi.nlm.nih.gov/30035254
Autor:
Habib Zaghouani, Alexis N. Cattin-Roy, Subhasis Barik, Jason S. Ellis, Jason A. Cascio, Tobechukwu K. Ukah, Mindy M. Miller
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(7)
IL-4 and IL-13 have been defined as anti-inflammatory cytokines that can counter myelin-reactive T cells and modulate experimental allergic encephalomyelitis. However, it is not known whether endogenous IL-4 and IL-13 contribute to the maintenance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d943e9485d86ff6d50e2b5e55933f78
https://pubmed.ncbi.nlm.nih.gov/28801358
https://pubmed.ncbi.nlm.nih.gov/28801358
Publikováno v:
The Journal of Immunology. 202:186.13-186.13
The RNA binding protein HuR directs helper T cell fate decisions by interacting with 3′ AU-rich elements within the untranslated region of multiple target mRNAs, leading to increased stability and transport to the heavy polysomes. We hypothesized t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eb2646f8d5ef2fdf00f0d10ed63195d
https://doi.org/10.4049/jimmunol.202.supp.186.13
https://doi.org/10.4049/jimmunol.202.supp.186.13
Publikováno v:
The Journal of Immunology. 191:4940-4949
NOD.H-2h4 mice given NaI in their drinking water develop iodine-accelerated spontaneous autoimmune thyroiditis (ISAT) with chronic inflammation of the thyroid by T and B cells and production of anti-mouse thyroglobulin (MTg) autoantibody. CD28−/−
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0187cc17561b6b266067fc9fbb801cb
https://doi.org/10.4049/jimmunol.1301253
https://doi.org/10.4049/jimmunol.1301253