Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Jason S, Knight"'
Autor:
Neda Kortam, Wenying Liang, Claire Shiple, Suiyuan Huang, Rosemary Gedert, James St. Clair, Cyrus Sarosh, Caroline Foster, Pei-Suen Tsou, John Varga, Jason S. Knight, Dinesh Khanna, Ramadan A. Ali
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Objectives Neutrophils and neutrophil extracellular traps (NETs) contribute to the vascular complications of multiple diseases, but their role in systemic sclerosis (SSc) is understudied. We sought to test the hypothesis that NETs are implic
Externí odkaz:
https://doaj.org/article/1e9423ad492e4ec5b83935972b964cf2
Autor:
Matthew C. Woodruff, Kevin S. Bonham, Fabliha A. Anam, Tiffany A. Walker, Caterina E. Faliti, Yusho Ishii, Candice Y. Kaminski, Martin C. Ruunstrom, Kelly Rose Cooper, Alexander D. Truong, Adviteeya N. Dixit, Jenny E. Han, Richard P. Ramonell, Natalie S. Haddad, Mark E. Rudolph, Srilakshmi Yalavarthi, Viktoria Betin, Ted Natoli, Sherwin Navaz, Scott A. Jenks, Yu Zuo, Jason S. Knight, Arezou Khosroshahi, F. Eun-Hyung Lee, Ignacio Sanz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract While immunologic correlates of COVID-19 have been widely reported, their associations with post-acute sequelae of COVID-19 (PASC) remain less clear. Due to the wide array of PASC presentations, understanding if specific disease features ass
Externí odkaz:
https://doaj.org/article/9d2aa0b3afa9462d9b276355450d5845
Autor:
Julia K. Weiner, Tristin Smith, Claire K. Hoy, Cyrus Sarosh, Jacqueline A. Madison, Amala Ambati, Ajay Tambralli, Noah Peters, Corinne Packel, Kelsey Gockman, Yu Zuo, Emily M. Briceño, Vivek Nagaraja, Jason S. Knight
Publikováno v:
ACR Open Rheumatology, Vol 5, Iss 1, Pp 28-37 (2023)
Objective This study assessed patient‐reported outcomes (PROs) in individuals with persistently positive antiphospholipid antibodies (aPL) to better understand how living with aPL may affect their quality of life. Methods Patients completed Patient
Externí odkaz:
https://doaj.org/article/afbc614d5f5c4be4be20f4182afb0293
Autor:
Ramadan A. Ali, Valerie C. Minarchick, Miela Zahavi, Christine E. Rysenga, Kristin A. Sturm, Claire K. Hoy, Cyrus Sarosh, Jason S. Knight, M. Kristen Demoruelle
Publikováno v:
JCI Insight, Vol 8, Iss 18 (2023)
We previously reported that treatment of mice with 6-gingerol, the most abundant phytochemical in ginger root, leads to phosphodiesterase inhibition that counteracts neutrophil hyperactivity in models of antiphospholipid syndrome (APS) and lupus. Her
Externí odkaz:
https://doaj.org/article/0cc77206541840b8a38e4f7e06189757
Autor:
Allison C. Billi, Rachael Wasikowski, Feiyang Ma, Srilakshmi Yalavarthi, Claire K. Hoy, Yu Zuo, Matthew T. Patrick, Neha Shah, Christine Parker, Chad Aaronson, Alyssa Harbaugh, Matthew F. Lucido, Kerby Shedden, Krishna Rao, Heidi B. IglayReger, Charles F. Burant, J. Michelle Kahlenberg, Lam C. Tsoi, Johann E. Gudjonsson, Jason S. Knight, Yogendra Kanthi
Publikováno v:
JCI Insight, Vol 8, Iss 16 (2023)
Risk of severe disease and death due to COVID-19 is increased in certain patient demographic groups, including those of advanced age, male sex, and obese body mass index. Investigations of the biological variations that contribute to this risk have b
Externí odkaz:
https://doaj.org/article/db7b5f12e7994ea49aa1f66cc4afaa01
Autor:
Ayesha Butt, Rolando Garcia-Milian, George Goshua, Sean Gu, John Hwa, Hyung Chun, H Michael Belmont, Nina Kello, D. Ware Branch, Michelle Petri, Jason S. Knight, Rohan Willis, Maria Laura Bertolaccini, Doruk Erkan, Alfred Lee, Anish Sharda, Alexander Pine
Publikováno v:
HemaSphere, Vol 7, p e160607f (2023)
Externí odkaz:
https://doaj.org/article/1b4dd1b3561e40a3a629ad3e8f68c2b5
Autor:
Bevin C. English, Hannah P. Savage, Scott P. Mahan, Vladimir E. Diaz-Ochoa, Briana M. Young, Basel H. Abuaita, Gautam Sule, Jason S. Knight, Mary X. O’Riordan, Andreas J. Bäumler, Renée M. Tsolis
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Immune cells must be able to adjust their metabolic programs to effectively carry out their effector functions. Here, we show that the endoplasmic reticulum (ER) stress sensor Inositol-requiring enzyme 1 alpha (IRE1α) and its downstream tra
Externí odkaz:
https://doaj.org/article/b52ea6eb6b7147e58bfa67beaabdb258
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background/purpose Pediatric antiphospholipid syndrome (APS) is a thromboinflammatory disease characterized by the presence of circulating antiphospholipid antibodies and either thrombotic events or pregnancy morbidity. The objective of this
Externí odkaz:
https://doaj.org/article/85c1129b3e234a788a93b483ed753196
Autor:
Erivelton de Azevedo Lopes, Gustavo Guimarães Moreira Balbi, Maria G. Tektonidou, Vittorio Pengo, Savino Sciascia, Amaia Ugarte, H. Michael Belmont, Maria Gerosa, Paul R. Fortin, Chary Lopez-Pedrera, Lanlan Ji, Hannah Cohen, Guilherme Ramires de Jesús, D. Ware Branch, Cecilia Nalli, Michelle Petri, Esther Rodriguez, Nina Kello, Roberto Ríos-Garcés, Jason S. Knight, Tatsuya Atsumi, Rohan Willis, Maria Laura Bertolaccini, Doruk Erkan, Danieli Andrade, APS ACTION
Publikováno v:
Advances in Rheumatology, Vol 61, Iss 1, Pp 1-6 (2021)
Abstract Background Antiphospholipid syndrome (APS) is characterized by episodes of thrombosis, obstetric morbidity or both, associated with persistently positive antiphospholipid antibodies (aPL). Studying the profile of a rare disease in an admixed
Externí odkaz:
https://doaj.org/article/715cecf8601841039c95b619557f5261
Autor:
Anna-Lisa E Lawrence, Ryan P Berger, David R Hill, Sha Huang, Veda K Yadagiri, Brooke Bons, Courtney Fields, Gautam J Sule, Jason S Knight, Christiane E Wobus, Jason R Spence, Vincent B Young, Mary X O'Riordan, Basel H Abuaita
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010855 (2022)
Infection of the human gut by Salmonella enterica Typhimurium (STM) results in a localized inflammatory disease that is not mimicked in murine infections. To determine mechanisms by which neutrophils, as early responders to bacterial challenge, direc
Externí odkaz:
https://doaj.org/article/bc7475739de7493a804ae366c621795c