Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Jason S, Iacovoni"'
Autor:
Salwa Soussi, Lesia Savchenko, Davide Rovina, Jason S. Iacovoni, Andrea Gottinger, Maxime Vialettes, Josè-Manuel Pioner, Andrea Farini, Sara Mallia, Martina Rabino, Giulio Pompilio, Angelo Parini, Olivier Lairez, Aoife Gowran, Nathalie Pizzinat
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-18 (2023)
Abstract Duchenne muscular dystrophy (DMD) is a severe form of muscular dystrophy caused by mutations in the dystrophin gene. We characterized which isoforms of dystrophin were expressed by human induced pluripotent stem cell (hiPSC)-derived cardiac
Externí odkaz:
https://doaj.org/article/bf3a762253b14d5b8a3a2000997579d2
Autor:
Salwa Soussi, Lesia Savchenko, Davide Rovina, Jason S. Iacovoni, Andrea Gottinger, Maxime Vialettes, Josè-Manuel Pioner, Andrea Farini, Sara Mallia, Martina Rabino, Giulio Pompilio, Angelo Parini, Olivier Lairez, Aoife Gowran, Nathalie Pizzinat
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/af7f4e2820cf4e1d923852bd68466e6f
Autor:
Camille Attané, David Estève, Karima Chaoui, Jason S. Iacovoni, Jill Corre, Mohamed Moutahir, Philippe Valet, Odile Schiltz, Nicolas Reina, Catherine Muller
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 949-958.e6 (2020)
Summary: Under caloric restriction, bone marrow adipocytes (BM-Ads) do not decrease in size compared to white adipocytes, suggesting they harbor unique metabolic properties. We compare human primary BM-Ads with paired subcutaneous adipocytes (SC-Ads)
Externí odkaz:
https://doaj.org/article/5547b4b9aa564743aa8344e58cdb4dd8
Autor:
Simon Nicolas, Vincent Blasco‐Baque, Audren Fournel, Jerome Gilleron, Pascale Klopp, Aurelie Waget, Franck Ceppo, Alysson Marlin, Roshan Padmanabhan, Jason S Iacovoni, François Tercé, Patrice D Cani, Jean‐François Tanti, Remy Burcelin, Claude Knauf, Mireille Cormont, Matteo Serino
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 3, Pp 1-17 (2017)
Abstract Gut microbiota dysbiosis has been implicated in a variety of systemic disorders, notably metabolic diseases including obesity and impaired liver function, but the underlying mechanisms are uncertain. To investigate this question, we transfer
Externí odkaz:
https://doaj.org/article/b955560a33e845d1b23e5d096d6e2b27
Autor:
Nathalie Boulet, Anaïs Briot, Valentin Jargaud, David Estève, Anne Rémaury, Chloé Belles, Pénélope Viana, Jessica Fontaine, Lucie Murphy, Catherine Déon, Marie Guillemot, Catherine Pech, Yaligara Veeranagouda, Michel Didier, Pauline Decaunes, Etienne Mouisel, Christian Carpéné, Jason S. Iacovoni, Alexia Zakaroff‐Girard, Jean‐Louis Grolleau, Jean Galitzky, Séverine Ledoux, Jean‐Claude Guillemot, Anne Bouloumié
Publikováno v:
Aging Cell
Aging Cell, 2023, pp.e13776. ⟨10.1111/acel.13776⟩
Aging Cell, 2023, pp.e13776. ⟨10.1111/acel.13776⟩
International audience; Senescence is a key event in the impairment of adipose tissue (AT) function with obesity and aging but the underlying molecular and cellular players remain to be fully defined, particularly with respect to the human AT progeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ac442cff8f911ad7821a8038f74af5
https://pubmed.ncbi.nlm.nih.gov/36617688
https://pubmed.ncbi.nlm.nih.gov/36617688
Autor:
Pierre Caron, Jonathan Choudjaye, Thomas Clouaire, Béatrix Bugler, Virginie Daburon, Marion Aguirrebengoa, Thomas Mangeat, Jason S. Iacovoni, Alejandro Álvarez-Quilón, Felipe Cortés-Ledesma, Gaëlle Legube
Publikováno v:
Cell Reports, Vol 13, Iss 8, Pp 1598-1609 (2015)
DNA double-strand breaks (DSBs) elicit the so-called DNA damage response (DDR), largely relying on ataxia telangiectasia mutated (ATM) and DNA-dependent protein kinase (DNA-PKcs), two members of the PI3K-like kinase family, whose respective functions
Externí odkaz:
https://doaj.org/article/ade3514d2cc9404f8b5668e7ba76674c
Autor:
Jean Personnaz, Enzo Piccolo, Alizée Dortignac, Jason S. Iacovoni, Jérôme Mariette, Vincent Rocher, Arnaud Polizzi, Aurélie Batut, Simon Deleruyelle, Lucas Bourdens, Océane Delos, Lucie Combes-Soia, Romain Paccoud, Elsa Moreau, Frédéric Martins, Thomas Clouaire, Fadila Benhamed, Alexandra Montagner, Walter Wahli, Robert F. Schwabe, Armelle Yart, Isabelle Castan-Laurell, Justine Bertrand-Michel, Odile Burlet-Schiltz, Catherine Postic, Pierre-Damien Denechaud, Cédric Moro, Gaelle Legube, Chih-Hao Lee, Hervé Guillou, Philippe Valet, Cédric Dray, Jean-Philippe Pradère
Publikováno v:
Science Advances
Science Advances, 2022, 8 (12), ⟨10.1126/sciadv.abg9055⟩
Science Advances, 2022, 8 (12), ⟨10.1126/sciadv.abg9055⟩
Dysregulations of lipid metabolism in the liver may trigger steatosis progression, leading to potentially severe clinical consequences such as nonalcoholic fatty liver diseases (NAFLDs). Molecular mechanisms underlying liver lipogenesis are very comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79eac556bb1af4b744201d38bffcecbf
https://hal.inrae.fr/hal-03624265/document
https://hal.inrae.fr/hal-03624265/document
Publikováno v:
Neurochemical Research
Neurochemical Research, 2022, 47 (8), pp.2416-2430. ⟨10.1007/s11064-022-03636-7⟩
Neurochemical Research, 2022, 47 (8), pp.2416-2430. ⟨10.1007/s11064-022-03636-7⟩
International audience; Myocardial infraction (MI) is the principal risk factor for the onset of heart failure (HF). Investigations regarding the physiopathology of MI progression to HF have revealed the concerted engagement of other tissues, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0a63b3647cb956b9d3cf5527db3218
https://hal.science/hal-03796221
https://hal.science/hal-03796221
Autor:
Alexis Piedrafita, Stanislas Faguer, Benjamin Breuil, Stéphane Decramer, Dominique Chauveau, Joost P. Schanstra, Myriam Malet-Martino, Stéphane Balayssac, Jean-Sébastien Saulnier-Blache, Jason S. Iacovoni, Alexandre Lucas, Audrey Casemayou
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (11), ⟨10.1096/fj.202100782RR⟩
FASEB Journal, 2021, 35 (11), pp.e21931. ⟨10.1096/fj.202100782RR⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (11), ⟨10.1096/fj.202100782RR⟩
FASEB Journal, 2021, 35 (11), pp.e21931. ⟨10.1096/fj.202100782RR⟩
International audience; Energetic metabolism controls key steps of kidney development, homeostasis, and epithelial repair following acute kidney injury (AKI). Hepatocyte nuclear factor-1β (HNF-1β) is a master transcription factor that controls mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced824e4dac0cb3d91d88b34e4b55bf8
https://pubmed.ncbi.nlm.nih.gov/34653285
https://pubmed.ncbi.nlm.nih.gov/34653285
Autor:
Romain Paccoud, Arnaud Polizzi, Isabelle Castan-Laurell, Jérôme Mariette, Robert F. Schwabe, W. Wahli, Frédéric Martins, Jason S. Iacovoni, Enzo Piccolo, Thomas Clouaire, Simon Deleruyelle, Chih-Hao Lee, Philippe Valet, Jean-Philippe Pradere, Gaëlle Legube, Fadila Benhamed, Hervé Guillou, Alexandra Montagner, Cedric Moro, Catherine Postic, Jean Personnaz, Elsa Moreau, Cédric Dray, Alizee Dortignac, Armelle Yart, Aurélie Batut
Dysregulations of lipid metabolism in the liver may trigger steatosis progression leading to potentially severe clinical consequences such as non-alcoholic fatty liver diseases (NAFLD). Molecular mechanisms underlying liver lipogenesis are very compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52bd111c8125f84f86d0f59c23a35b9e
https://doi.org/10.1101/2021.02.17.431446
https://doi.org/10.1101/2021.02.17.431446