Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jason Rexroad"'
Autor:
Samadhi N. Vitharana, LaToya S. Jones, C. Russell Middaugh, Ambarish Shah, Melissa D. Perkins, Adeola O. Grillo, Thomas Spitznagel, Tiffany Derrick, Jason Rexroad
Publikováno v:
Journal of Pharmaceutical Sciences. 96:761-776
The interaction of several of the fibroblast growth factors (FGFs) with polyanions is thought to be of physiological significance and has been exploited to create more stable pharmaceutical formulations of FGF-1 and -2. The extent of such phenomena t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf331e3c0936fbdf3f8c359c9b30df1e
https://doi.org/10.1002/jps.20797
https://doi.org/10.1002/jps.20797
Publikováno v:
Journal of Pharmaceutical Sciences. 95:237-247
The thermal stability of adenovirus type 5 (Ad5) was investigated over the pH range 3-8 employing a variety of biophysical techniques under conditions of low and high ionic strength. Analysis of the structural stability of Ad5 by dynamic light scatte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a1e48cd4462ae749b766dc49487b98
https://doi.org/10.1002/jps.20496
https://doi.org/10.1002/jps.20496
Autor:
Duane T. Brandau, Jason Rexroad, LaToya S. Jones, C. Russell Middaugh, Christopher M. Wiethoff
Publikováno v:
Journal of Pharmaceutical Sciences. 92:218-231
Worldwide vaccination programs against infectious diseases and toxins are estimated to save approximately 3 million lives yearly. Tragically, however, another 3 million individuals (primarily children) die of vaccine-preventable diseases. A significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99cfebe1666560464452344c71718141
https://doi.org/10.1002/jps.10296
https://doi.org/10.1002/jps.10296
Publikováno v:
Cell Preservation Technology. 1:91-104
Currently, vaccines are developed as either lyophilized or aqueous formulations; however, the inherent lack of vaccine thermostability requires storage at subambient temperatures. In the developing world, meeting these storage requirements can be dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77b67dfa5913706039acb5710968bd95
https://doi.org/10.1089/153834402320882593
https://doi.org/10.1089/153834402320882593
Publikováno v:
Journal of pharmaceutical sciences. 95(7)
Although several recent studies have focused on the characterization and formulation of adenovirus type 5, similar efforts focusing on adenovirus type 2 (Ad2) have been lacking. To this end, multiple biophysical techniques were employed to investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892027312cb83f2d3dec398441461c10
https://pubmed.ncbi.nlm.nih.gov/16724322
https://pubmed.ncbi.nlm.nih.gov/16724322
Autor:
Miller O. Scott, Christopher M. Wiethoff, Anthony P. Green, C. Russell Middaugh, Jason Rexroad, Timothy D. Kierstead
Publikováno v:
Journal of pharmaceutical sciences. 92(3)
Thermally induced structural changes in adenovirus type 5 (Ad) in the presence of either 2 or 10% sucrose were investigated using a variety of biophysical techniques. In solutions containing 2% sucrose, a highly cooperative transition in the structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f54f2f44dff85a0a9de71d3b0cc9b6
https://pubmed.ncbi.nlm.nih.gov/12587128
https://pubmed.ncbi.nlm.nih.gov/12587128
Publikováno v:
Cell Preservation Technology; Jun2002, Vol. 1 Issue 2, p91-104, 14p