Zobrazeno 1 - 10
of 237
pro vyhledávání: '"Jason Reed"'
Autor:
Daniel Malouli, Meenakshi Tiwary, Roxanne M. Gilbride, David W. Morrow, Colette M. Hughes, Andrea Selseth, Toni Penney, Priscila Castanha, Megan Wallace, Yulia Yeung, Morgan Midgett, Connor Williams, Jason Reed, Yun Yu, Lina Gao, Gabin Yun, Luke Treaster, Amanda Laughlin, Jeneveve Lundy, Jennifer Tisoncik-Go, Leanne S. Whitmore, Pyone P. Aye, Faith Schiro, Jason P. Dufour, Courtney R. Papen, Husam Taher, Louis J. Picker, Klaus Früh, Michael Gale, Nicholas J. Maness, Scott G. Hansen, Simon Barratt-Boyes, Douglas S. Reed, Jonah B. Sacha
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract An influenza vaccine approach that overcomes the problem of viral sequence diversity and provides long-lived heterosubtypic protection is urgently needed to protect against pandemic influenza viruses. Here, to determine if lung-resident effe
Externí odkaz:
https://doaj.org/article/30aee6ee13914e60b17c02c57c123179
Autor:
Gaspar Mbita, Amasha Mwanamsangu, Albert N. Komba, Caterina Casalini, Maneno Luponya, Kelly Curran, Alice Christensen, Young-Mi Kim, Jason Reed, Neema Makyao, Upendo Kategile, Donaldson F. Conserve, Jos van Roosmalen, Thomas van den Akker
Publikováno v:
Frontiers in Reproductive Health, Vol 6 (2024)
IntroductionIn 2016, UNAIDS set ambitious targets to reduce global HIV infections by 75% by 2020 and 90% by 2030, based on the 2.1 million new infections reported in 2010. However, by 2022, new HIV infections had only decreased by 38%, from 2.1 milli
Externí odkaz:
https://doaj.org/article/f62a346f3dcb463fbd0fda37aacfa9cc
Autor:
Steven Forsythe, Urbanus Kioko, Guy Mahiane, Robert Glaubius, Abednego Musau, Anthony Gichangi, Jason Reed, Daniel Were
Publikováno v:
Frontiers in Reproductive Health, Vol 6 (2024)
BackgroundKenya included oral PrEP in the national guidelines as part of combination HIV prevention, and subsequently began providing PrEP to individuals who are at elevated risk of HIV infection in 2017. However, as scale-up continued, there was a r
Externí odkaz:
https://doaj.org/article/5e146fc6b1eb483db556153832c1aa76
Autor:
Griffins O. Manguro, Abednego M. Musau, Daniel K. Were, Soud Tengah, Brian Wakhutu, Jason Reed, Marya Plotkin, Stanley Luchters, Peter Gichangi, Marleen Temmerman
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Female sex workers (FSW) and men having sex with men (MSM) in Kenya have high rates of HIV infection. Following a 2015 WHO recommendation, Kenya initiated national scale-up of pre-exposure prophylaxis (PrEP) for all persons at hig
Externí odkaz:
https://doaj.org/article/35058a6c400045b4a24d22fd3513a2e1
Autor:
Viktoriya Zelikson, Roy Sabo, Myrna Serrano, Younus Aqeel, Savannah Ward, Taha Al Juhaishi, May Aziz, Elizabeth Krieger, Gary Simmons, Catherine Roberts, Jason Reed, Gregory Buck, Amir Toor
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 7, Pp n/a-n/a (2023)
Abstract Objectives Immune recovery following haematopoietic cell transplantation (HCT) functions as a dynamical system. Reducing the duration of intense immune suppression and augmenting antigen presentation has the potential to optimise T‐cell re
Externí odkaz:
https://doaj.org/article/ec09429bfc8f41c29d55e0073d8b2eca
Autor:
Mercy Kamau, Abednego Musau, Daniel Were, Gladys Waruguru, Mark Kabue, Jane Mutegi, Marya Plotkin, Jason Reed
Publikováno v:
Frontiers in Global Women's Health, Vol 2 (2022)
BackgroundFemale sex workers (FSWs) experience a higher risk for both HIV acquisition and unwanted pregnancies compared to women in the general population. Pre-exposure prophylaxis (PrEP) for HIV prevention offers protection against HIV infection but
Externí odkaz:
https://doaj.org/article/e0f176553f1248d480df502397c686f2
Autor:
Tareq Saleh, Valerie J. Carpenter, Liliya Tyutyunyk‐Massey, Graeme Murray, Joel D. Leverson, Andrew J. Souers, Moureq R. Alotaibi, Anthony C. Faber, Jason Reed, Hisashi Harada, David A. Gewirtz
Publikováno v:
Molecular Oncology, Vol 14, Iss 10, Pp 2504-2519 (2020)
Tumor cells undergo senescence in response to both conventional and targeted cancer therapies. The induction of senescence in response to cancer therapy can contribute to unfavorable patient outcomes, potentially including disease relapse. This possi
Externí odkaz:
https://doaj.org/article/b1ca93626c5148b4a9daf8f17d95e358
Autor:
Mariya B. Shapiro, Tracy Cheever, Delphine C. Malherbe, Shilpi Pandey, Jason Reed, Eun Sung Yang, Keyun Wang, Amarendra Pegu, Xuejun Chen, Don Siess, David Burke, Heidi Henderson, Rebecca Lewinsohn, Miranda Fischer, Jeffrey J. Stanton, Michael K. Axthelm, Christoph Kahl, Byung Park, Anne D. Lewis, Jonah B. Sacha, John R. Mascola, Ann J. Hessell, Nancy L. Haigwood
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Broadly neutralizing antibodies (bNAbs) are being evaluated for HIV post-exposure prophylaxis (PEP) in the setting of vertical transmission. Here, using a macaque model of perinatal SHIV infection, the authors show that PEP for infant macaques within
Externí odkaz:
https://doaj.org/article/96930173c51d4c149db6d9fcbe66090f
Autor:
Kaitlyn Atkins, Abednego Musau, Mary Mugambi, Geoffrey Odhyambo, Soud Ali Tengah, Mercy Kamau, Ruth Kumau, Jason Reed, Daniel Were
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0259738 (2022)
BackgroundAs pre-exposure prophylaxis (PrEP) scales up in sub-Saharan Africa, governments and implementers need to understand how to best manage national programs. Kenya's national PrEP program offers an opportunity to review elements of program succ
Externí odkaz:
https://doaj.org/article/00993300ca9640e7a4f1ef3d9139342a
Autor:
Narmeen S. Rashid, Nicole S. Hairr, Graeme Murray, Amy L. Olex, Tess J. Leftwich, Jacqueline M. Grible, Jason Reed, Mikhail G. Dozmorov, J. Chuck Harrell
Publikováno v:
Translational Oncology, Vol 14, Iss 12, Pp 101235- (2021)
An estimated 284,000 Americans will be diagnosed with breast cancer in 2021. Of these individuals, 15–20% have basal-like triple-negative breast cancer (TNBC), which is known to be highly metastatic. Chemotherapy is standard of care for TNBC patien
Externí odkaz:
https://doaj.org/article/05480dffed8743abb64d01e1607ab512