Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jason R. Stubbs"'
Autor:
Kyle P. Jansson, Jordan Kuluva, Shiqin Zhang, Taylor Swanson, Yan Zhang, Kurt A. Zimmerman, Timothy A. Fields, Darren P. Wallace, Peter S. Rowe, Jason R. Stubbs
Publikováno v:
Physiological Reports, Vol 12, Iss 17, Pp n/a-n/a (2024)
Abstract Osteopontin (OPN) is a multi‐functional glycoprotein that coordinates the innate immune response, prevents nanocrystal formation in renal tubule fluid, and is a biomarker for kidney injury. OPN expression is markedly increased in cystic ep
Externí odkaz:
https://doaj.org/article/15be34ec754f420ba0668b95d8c7b8af
Autor:
Katherine I. Swenson-Fields, Christopher J. Ward, Micaila E. Lopez, Shaneann Fross, Anna L. Heimes Dillon, James D. Meisenheimer, Adib J. Rabbani, Emily Wedlock, Malay K. Basu, Kyle P. Jansson, Peter S. Rowe, Jason R. Stubbs, Darren P. Wallace, Michael P. Vitek, Timothy A. Fields
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
We and others have previously shown that the presence of renal innate immune cells can promote polycystic kidney disease (PKD) progression. In this study, we examined the influence of the inflammasome, a key part of the innate immune system, on PKD.
Externí odkaz:
https://doaj.org/article/9c08d54c8b8b492abf160be7de40df31
Autor:
Mireille El Ters, Pengcheng Lu, Jonathan D. Mahnken, Jason R. Stubbs, Shiqin Zhang, Darren P. Wallace, Jared J. Grantham, Arlene B. Chapman, Vicente E. Torres, Peter C. Harris, Kyongtae Ty Bae, Douglas P. Landsittel, Frederic F. Rahbari-Oskoui, Michal Mrug, William M. Bennett, Alan S.L. Yu
Publikováno v:
Kidney International Reports, Vol 6, Iss 4, Pp 953-961 (2021)
Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive cyst growth and a loss of functioning renal mass, but a decline in glomerular filtration rate (GFR) and onset of end-stage renal disease (ESRD) occur l
Externí odkaz:
https://doaj.org/article/8beb5b69c3a14ce4bc60ffbad23c4ea5
Autor:
Carlee I. Oakley, David Sanborn, Nikita Rafie, Matt Hendrix, Michael Grillo, Julian Vallejo, Jason R. Stubbs, Tilitha Shawgo, Emmanuel Daon, George Zorn, Michael J. Wacker
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 30-30 (2018)
OBJECTIVES/SPECIFIC AIMS: The objective of this study was to determine if trimethylamine N-oxide (TMAO) alone could acutely alter cardiac contractile function on a beat-to-beat basis. METHODS/STUDY POPULATION: CD1 adult mouse hearts were extracted, a
Externí odkaz:
https://doaj.org/article/0bb88c7054da45be92dc7ae879b9984e
Autor:
Jason R. Stubbs, Shiqin Zhang, Kyle P. Jansson, Timothy A. Fields, Joseph Boulanger, Shiguang Liu, Peter S. Rowe
Publikováno v:
Kidney360
Nephron loss dramatically increases tubular phosphate to concentrations that exceed supersaturation. Osteopontin (OPN) is a matricellular protein that enhances mineral solubility in solution; however, the role of OPN in maintaining urinary phosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5e5a8a05ec13c14f7536184ec7329f
https://doi.org/10.34067/kid.0007352021
https://doi.org/10.34067/kid.0007352021
Autor:
Heather A. L. Riddle, Shiqin Zhang, Feng Qian, James C. Williams, Jason R. Stubbs, Peter Stanley N. Rowe, Stephen C. Parnell
Publikováno v:
Am J Physiol Renal Physiol
Individuals with autosomal dominant polycystic kidney disease have a higher incidence of stone formation than the general population. However, there are no cystic animal models known to develop stones. Cystic mice compound heterozygous for hypomorphi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32146a0e97a9c85a6fa5be739b48716
https://doi.org/10.1152/ajprenal.00165.2021
https://doi.org/10.1152/ajprenal.00165.2021
Autor:
Shiqin Zhang, Kyongtae T. Bae, Vicente E. Torres, William M. Bennett, Douglas Landsittel, Frederic F. Rahbari-Oskoui, Jared J. Grantham, Jason R. Stubbs, Pengcheng Lu, Mireille El Ters, Jonathan D. Mahnken, Darren P. Wallace, Peter C. Harris, Michal Mrug, Alan S.L. Yu, Arlene B. Chapman
Publikováno v:
Kidney International Reports, Vol 6, Iss 4, Pp 953-961 (2021)
Kidney International Reports
Kidney International Reports
Introduction Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive cyst growth and a loss of functioning renal mass, but a decline in glomerular filtration rate (GFR) and onset of end-stage renal disease (ESRD) occur la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89bafa5b87c66b4a276caf01d608fa30
https://doi.org/10.1016/j.ekir.2021.01.004
https://doi.org/10.1016/j.ekir.2021.01.004
Autor:
James B. Wetmore, Jason R. Stubbs
Publikováno v:
Nephrology Self-Assessment Program. 19:206-214
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c260e9af49a661401ebe2aa094cfbc3a
https://doi.org/10.1681/nsap.2020.19.3.3
https://doi.org/10.1681/nsap.2020.19.3.3
Publikováno v:
Curr Opin Nephrol Hypertens
PURPOSE OF THE REVIEW: Progressive forms of chronic kidney disease (CKD) exhibit kidney inflammation and fibrosis that drive continued nephron loss; however, factors responsible for the development of these common pathologic features remain poorly de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f28a5f1f8a61e76773e25c1406a78b1
https://europepmc.org/articles/PMC9232955/
https://europepmc.org/articles/PMC9232955/
Autor:
Michel Chonchol, Anna Jovanovich, Charles E. Robertson, Thomas D. Nolin, Bryan Kestenbaum, Andrew N. Hoofnagle, Daniel N. Frank, Alexander J. Prokopienko, Jason R. Stubbs, Shiqin Zhang, Cassandra Johnson, Raymond E. West, Diana Ir, Cassandra Kimber, Makoto Miyazaki, Jonathan D. Mahnken, Alan S.L. Yu
Publikováno v:
Kidney360
Background Recent evidence suggests the systemic accumulation of by-products of gut microbes contributes to cardiovascular morbidity in patients with CKD. Limiting the generation of toxic bacterial by-products by manipulating the intestinal microbiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf37c33a96a394f2cd9cbfd1a6fc6e6
https://doi.org/10.34067/kid.0003942020
https://doi.org/10.34067/kid.0003942020