Oxygen dependence of nitric oxide-mediated signaling

Autor: Jason R. Hickok, Divya Vasudevan, Kate Jablonski, Douglas D. Thomas

Publikováno v: Redox Biology, Vol 1, Iss 1, Pp 203-209 (2013)

Nitric oxide (·NO) is a biologically important short-lived free radical signaling molecule. Both the enzymatic synthesis and the predominant forms of cellular metabolism of ·NO are oxygen-dependent. For these reasons, changes in local oxygen concen

Externí odkaz: https://doaj.org/article/8d6f199c467e4f32965fe774e101cada

Supplementary Materials and Methods, Supplementary Figures 1 through 4 and Supplementary Tables 1 through 4 from Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications

Autor: Douglas D. Thomas, Benjamin A. Garcia, Mark Maienschein-Cline, Xing-Jun Cao, Pinal Kanabar, Neil Bahroos, Lin L. Mantell, Vy Pham, Rhea C. Bovee, Jason R. Hickok, Divya Vasudevan

Supplementary Materials and Methods. Figure S1. Nitric oxide induces significant changes in histone posttranslational modifications. Figure S2. NO-mediated gene expression changes are consistent with the induction of an oncogenic phenotype. Figure S3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98812b65f6f9f58db34898fe47c8ab3f
https://doi.org/10.1158/0008-5472.22407869.v1

Epigenetics: The third pillar of nitric oxide signaling

Autor: Rhea C. Bovee, Douglas D. Thomas, Samantha Socco, Marianne B. Palczewski, Jason R. Hickok

Publikováno v: Pharmacological Research. 121:52-58

Nitric oxide (NO), the endogenously produced free radical signaling molecule, is generally thought to function via its interactions with heme-containing proteins, such as soluble guanylyl cyclase (sGC), or by the formation of protein adducts containi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1798d4e9345fe686a2fc5f10a34bbff8
https://doi.org/10.1016/j.phrs.2017.04.011

Contributors

Autor: Amrita Ahluwalia, Takaaki Akaike, María Noel Álvarez, Roger A. Alvarez, Debashree Basudhar, Christopher L. Bianco, Timothy R. Billiar, Rhea C. Bovee, Paul S. Brookes, Laura Castro, Robert Y.S. Cheng, Natalia Correa-Aragunde, Miriam M. Cortese-Krott, Meihong Deng, Qiang Du, Raul A. Dulce, Ulrich Förstermann, Martin Feelisch, Ingrid Fleming, Noelia Foresi, Bruce A. Freeman, Julia Fritsch, Jon M. Fukuto, David A. Geller, Mark T. Gladwin, Hartmut Grasemann, Madison Greer, Joshua M. Hare, Jason R. Hickok, Neil Hogg, Fernando Holguin, Fumito Ichinose, Daniel A. Jones, Balaraman Kalyanaraman, Gregory J. Kato, Eric E. Kelley, Malte Kelm, Christopher G. Kevil, Christopher Kevil, Daniel B. Kim-Shapiro, Doris Koesling, Christian M. Kramer, Shathiyah Kulandavelu, Yoshito Kumagai, Lorenzo Lamattina, Jack R. Lancaster, Zhao Lei, Huige Li, Stuart A. Lipton, Patricia A. Loughran, Jon O. Lundberg, Evanthia Mergia, Claudia R. Morris, Péter Nagy, Tomohiro Nakamura, Andreas Papapetropoulos, Rakesh P. Patel, Michaela Pekarova, Lucía Piacenza, Carolina Prolo, Natalia Ríos, Rafael Radi, Krishnaraj S. Rathod, Lisa A. Ridnour, Homero Rubbo, Michael Russwurm, Tomohiro Sawa, Ivonne Hernandez Schulman, Jeremy A. Scott, Sruti Shiva, Veena Somasundaram, Adam C. Straub, Csaba Szabo, Douglas D. Thomas, John P. Toscano, Andres Trostchansky, Divya Vasudevan, Eddie Weitzberg, David A. Wink, Daniel E. Winnica, Katherine C. Wood, Li Xu, Shuai Yuan, Warren M. Zapol, Jacek Zielonka

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4af64ee4daf30a0c6431c745dca833b3
https://doi.org/10.1016/b978-0-12-804273-1.00032-6

Oxygen dependence of nitric oxide-mediated signaling

Autor: Kate Jablonski, Divya Vasudevan, Jason R. Hickok, Douglas D. Thomas

Publikováno v: Redox Biology
Redox Biology, Vol 1, Iss 1, Pp 203-209 (2013)

Nitric oxide (•NO) is a biologically important short-lived free radical signaling molecule. Both the enzymatic synthesis and the predominant forms of cellular metabolism of •NO are oxygen-dependent. For these reasons, changes in local oxygen conc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7408628fe1a4aaf6445e3a7a5e7dd4