Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jason R. Hasenstein"'
Autor:
Jason R. Hasenstein, Kelsey Kasmerchak, Darya Buehler, Gholam Reza Hafez, Kevin Cleary, John S. Moody, Kevin R. Kozak
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 2, Pp 131-140 (2012)
Angiosarcomas are malignant endothelial cell tumors with few effective systemic treatments. Despite a unique endothelial origin, molecular candidates for targeted therapeutic intervention have been elusive. In this study, we explored the tunica inter
Externí odkaz:
https://doaj.org/article/4207d6ad542e4281a2ee45806b6a8c9a
Autor:
Kevin R. Kozak, Glen S. Kwon, Darya Buehler, Kelsey Kasmerchak, Ho-Chul Shin, Jason R. Hasenstein
PDF file, 320K, Acute histopathologic effects of paclitaxel-containing micelles and Triolimus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624e17211e530618b7730c600a5824f8
https://doi.org/10.1158/1535-7163.22497859.v1
https://doi.org/10.1158/1535-7163.22497859.v1
Autor:
Kevin R. Kozak, Glen S. Kwon, Darya Buehler, Kelsey Kasmerchak, Ho-Chul Shin, Jason R. Hasenstein
PDF file, 109K, Toxicity of paclitaxel-containing micelles and Triolimus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0721e6dd663fba94e9e4f4e419bad6ed
https://doi.org/10.1158/1535-7163.22497853
https://doi.org/10.1158/1535-7163.22497853
Autor:
Hafez Gr, Darya Buehler, Patrick S. Rush, Stephanie R. Rice, Jason R. Hasenstein, B. Jack Longley, Kevin R. Kozak
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Angiosarcoma is an aggressive malignancy of endothelial differentiation. Potential roles of the endothelial angiopoietin-tunica interna endothelial cell kinase (ANGPT-TIE) system in angiosarcoma diagnosis, pathogenesis, prognosis and treatment are un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ed6c812cb181652a6baf9fed3ac3e9
http://europepmc.org/articles/PMC3706492
http://europepmc.org/articles/PMC3706492
Autor:
Kevin R. Kozak, Kelsey Kasmerchak, Ho-Chul Shin, Darya Buehler, Glen S. Kwon, Jason R. Hasenstein
Publikováno v:
Molecular Cancer Therapeutics. 11:2233-2242
Triolimus is a first-in-class, multidrug-loaded micelle containing paclitaxel, rapamycin, and 17-AAG. In this study, we examine the antitumor mechanisms of action, efficacy, and toxicity of Triolimus in vitro and in vivo. In vitro cytotoxicity testin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f75f9acac9312f5b29372e384470e7b
https://doi.org/10.1158/1535-7163.mct-11-0987
https://doi.org/10.1158/1535-7163.mct-11-0987
Autor:
William F. Dove, Michael A. Newton, James M. Amos-Landgraf, Lacy L. Sommer, Andrew T. Thliveris, Barry Schoenike, Caroline M. Alexander, Cassandra L. Schlamp, Jason R. Hasenstein, Linda Clipson
Publikováno v:
G3: Genes|Genomes|Genetics
The gene-trap lacZ reporter insertion, ROSA11, in the Cbx5 mouse gene illuminates the regulatory complexity of this locus in ApcMin/+ mice. The insertion site of the β-Geo gene-trap element lies in the 24-kb intron proximal to the coding region of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb991f0b1777672f0b0e003883f03896
https://doi.org/10.1534/g3.112.002436
https://doi.org/10.1534/g3.112.002436
Publikováno v:
Poultry Science. 87:22-26
Salmonella enteritidis lipopolysaccharide stimulates interleukin 10 (IL10) gene expression in chickens. Four genes in the IL10 cluster [polymeric immunoglobulin receptor (PIGR), interleukin 10 (IL10), map kinase-activated protein kinase 2 (MAPKAPK2),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81785ff727f92a5f9e614957077b174f
https://doi.org/10.3382/ps.2007-00259
https://doi.org/10.3382/ps.2007-00259
Publikováno v:
Infection and Immunity. 74:3375-3380
Gallinacins in poultry are functional equivalents of mammalian beta-defensins, which constitute an integral component of the innate immune system. Salmonella enterica serovar Enteritidis is a gram-negative bacterium that negatively affects both human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b61b5e530f80a6ac0ff0ed28bbcd22e
https://doi.org/10.1128/iai.00027-06
https://doi.org/10.1128/iai.00027-06
Autor:
C. Blake Gilks, Avinash M. Baktula, Sara E. Meyer, Chinavenmani S. Velu, Huajing Wan, Yan Xu, Jeffrey A. Whitsett, H. Leighton Grimes, Jason R. Hasenstein
K-RAS mutations are found in approximately 30% of lung cancers. The transcription factor Krüppel-like Factor 5 (KLF5) has been shown to mediate cellular transformation signaling events downstream of oncogenic RAS in other cancers, but a role for KLF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5af188f606c1f0d124ac2787fd135b
https://europepmc.org/articles/PMC2928981/
https://europepmc.org/articles/PMC2928981/