Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Jason R. Cannon"'
Autor:
Fabiola De Marchi, Ivana Munitic, Lea Vidatic, Eliša Papić, Valentino Rački, Jerneja Nimac, Igor Jurak, Gabriela Novotni, Boris Rogelj, Vladimira Vuletic, Rajka M. Liscic, Jason R. Cannon, Emanuele Buratti, Letizia Mazzini, Silva Hecimovic
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2793 (2023)
Many potential immune therapeutic targets are similarly affected in adult-onset neurodegenerative diseases, such as Alzheimer’s (AD) disease, Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD), as wel
Externí odkaz:
https://doaj.org/article/473fce8945424961988b168cd6f23534
Autor:
Fabiola De Marchi, Toni Franjkic, Paride Schito, Tommaso Russo, Jerneja Nimac, Anna A. Chami, Angelica Mele, Lea Vidatic, Jasna Kriz, Jean-Pierre Julien, Gordana Apic, Robert B. Russell, Boris Rogelj, Jason R. Cannon, Marco Baralle, Federica Agosta, Silva Hecimovic, Letizia Mazzini, Emanuele Buratti, Ivana Munitic
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1599 (2023)
Proteinopathy and neuroinflammation are two main hallmarks of neurodegenerative diseases. They also represent rare common events in an exceptionally broad landscape of genetic, environmental, neuropathologic, and clinical heterogeneity present in pat
Externí odkaz:
https://doaj.org/article/1d4499cfcc20462c9f6f60178f9f2d72
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Neurological hazard assessment of industrial and pesticidal chemicals demands a substantial amount of time and resources. Caenorhabditis elegans is an established model organism in developmental biology and neuroscience. It presents an ideal test sys
Externí odkaz:
https://doaj.org/article/0025c97d50a34ea288c6aefebda6a328
Autor:
April A. Dukes, Qing Bai, Victor S. Van Laar, Yangzhong Zhou, Vladimir Ilin, Christopher N. David, Zeynep S. Agim, Joshua L. Bonkowsky, Jason R. Cannon, Simon C. Watkins, Claudette M. St. Croix, Edward A. Burton, Sarah B. Berman
Publikováno v:
Neurobiology of Disease, Vol 95, Iss , Pp 238-249 (2016)
Extensive convergent evidence collectively suggests that mitochondrial dysfunction is central to the pathogenesis of Parkinson's disease (PD). Recently, changes in the dynamic properties of mitochondria have been increasingly implicated as a key prox
Externí odkaz:
https://doaj.org/article/8b9ae28de4dc45a9af85f22ac60ebbde
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
The motor features of Parkinson's disease (PD) primarily result from a lesion to the nigrostriatal dopamine system. Numerous non-motor symptoms occur in PD, many of which are postulated to stem from pathology outside of the nigrostriatal dopamine sys
Externí odkaz:
https://doaj.org/article/73fd46b04b514ec0b9c6dda19dcb24ff
Publikováno v:
Neurobiology of Disease, Vol 73, Iss , Pp 356-365 (2015)
Repeated seizures are often associated with development of refractory chronic epilepsy, the most common form of which is temporal lobe epilepsy. G-protein-coupled cannabinoid receptors (CB1 and CB2 receptors) regulate neuronal excitability and have b
Externí odkaz:
https://doaj.org/article/8ffd5129cb614a2f87a17629050e3804
Autor:
Jason R. Cannon, J. Timothy Greenamyre
Publikováno v:
Neurobiology of Disease, Vol 57, Iss , Pp 38-46 (2013)
Interactions between genetic factors and environmental exposures are thought to be major contributors to the etiology of Parkinson's disease. While such interactions are poorly defined and incompletely understood, recent epidemiological studies have
Externí odkaz:
https://doaj.org/article/fa24be48ac15474fbd5fa86bc5bd5dab
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 1, Pp 96-102 (2009)
Gastrointestinal disorders, particularly severe constipation and delayed gastric emptying, are core symptoms of Parkinson's disease that affect most patients. However, the neuropathological substrate and physiological basis for this dysfunction are p
Externí odkaz:
https://doaj.org/article/2f41af552f1a4027a459a33302118ac1
Autor:
Jason R. Cannon, Victor Tapias, Hye Mee Na, Anthony S. Honick, Robert E. Drolet, J. Timothy Greenamyre
Publikováno v:
Neurobiology of Disease, Vol 34, Iss 2, Pp 279-290 (2009)
The systemic rotenone model of Parkinson's disease (PD) accurately replicates many aspects of the pathology of human PD and has provided insights into the pathogenesis of PD. The major limitation of the rotenone model has been its variability, both i
Externí odkaz:
https://doaj.org/article/e3f9d1d256e44950b12893974ac97549
Autor:
Regina F. Fernandez, Emily S. Wilson, Victoria Diaz, Jonatan Martínez‐Gardeazabal, Rachel Foguth, Jason R. Cannon, Shelley N. Jackson, Brian P. Hermann, Jeffrey B. Eells, Jessica M. Ellis
Publikováno v:
Journal of Neurochemistry. 165:379-390