Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jason R. Betley"'
Autor:
Mark A. T. Blaskovich, Karl A. Hansford, Yujing Gong, Mark S. Butler, Craig Muldoon, Johnny X. Huang, Soumya Ramu, Alberto B. Silva, Mu Cheng, Angela M. Kavanagh, Zyta Ziora, Rajaratnam Premraj, Fredrik Lindahl, Tanya A. Bradford, June C. Lee, Tomislav Karoli, Ruby Pelingon, David J. Edwards, Maite Amado, Alysha G. Elliott, Wanida Phetsang, Noor Huda Daud, Johan E. Deecke, Hanna E. Sidjabat, Sefetogi Ramaologa, Johannes Zuegg, Jason R. Betley, Andrew P. G. Beevers, Richard A. G. Smith, Jason A. Roberts, David L. Paterson, Matthew A. Cooper
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The antibiotic vancomycin inhibits bacterial cell wall synthesis by binding to a membrane-associated precursor. Here, Blaskovich et al. synthesize vancomycin derivatives containing lipophilic peptide moieties that enhance membrane affinity and in viv
Externí odkaz:
https://doaj.org/article/5939bc54d4b347d7b1b16946d6d5c490
Autor:
Olga Tosas Auguet, Jason R Betley, Richard A Stabler, Amita Patel, Avgousta Ioannou, Helene Marbach, Pasco Hearn, Anna Aryee, Simon D Goldenberg, Jonathan A Otter, Nergish Desai, Tacim Karadag, Chris Grundy, Michael W Gaunt, Ben S Cooper, Jonathan D Edgeworth, Theodore Kypraios
Publikováno v:
PLoS Medicine, Vol 13, Iss 1, p e1001944 (2016)
BackgroundIdentifying and tackling the social determinants of infectious diseases has become a public health priority following the recognition that individuals with lower socioeconomic status are disproportionately affected by infectious diseases. I
Externí odkaz:
https://doaj.org/article/5ed19960f52b435a93a748b78347c773
Autor:
Andreas Plückthun, Hazel Denham, James H. Rickard, G. Michael Blackburn, Abdelaziz Mekhalfia, Jason R. Betley, Sandro Cesaro-Tadic, Lynda J. Partridge
Publikováno v:
Angewandte Chemie. 114:801-803
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f052480008e6c7689b6e5bc7824af3
https://doi.org/10.1002/1521-3757(20020301)114:5<801::aid-ange801>3.0.co
https://doi.org/10.1002/1521-3757(20020301)114:5<801::aid-ange801>3.0.co
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 288
For the first time a new, two-step method is described for synthesizing deoxyribonucleic acid. The approach uses 5'-carbonate protected 2'-deoxynucleoside-3'-phosphoramidites as synthons and a peroxy anion buffer that removes the carbonate protecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53a803bed709f99f779dfd4639eae2c9
https://pubmed.ncbi.nlm.nih.gov/15333894
https://pubmed.ncbi.nlm.nih.gov/15333894
For the first time a new, two-step method is described for synthesizing deoxyribonucleic acid. The approach uses 5'-carbonate protected 2'-deoxynucleoside-3'-phosphoramidites as synthons and a peroxy anion buffer that removes the carbonate protecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff50256bdd5e9f2ea237c35aee7c8c84
https://doi.org/10.1385/1-59259-823-4:001
https://doi.org/10.1385/1-59259-823-4:001
Autor:
Marvin H. Caruthers, Tadeusz K. Wyrzykiewicz, Douglas J. Dellinger, Jason R. Betley, Agnieszka B. Sierzchala, Christina M. Yamada
Publikováno v:
Journal of the American Chemical Society. 125(44)
A novel solid-phase phosphoramidite based oligodeoxynucleotide two-step synthesis method has been developed. Keys to this method are replacement of the 5'-dimethoxytrityl blocking group with an aryloxycarbonyl and the use of N-dimethoxytrityl protect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745d78ea28541b2c22ceed1ea746381d
https://pubmed.ncbi.nlm.nih.gov/14583038
https://pubmed.ncbi.nlm.nih.gov/14583038
Autor:
Jason R, Betley, Sandro, Cesaro-Tadic, Abdelaziz, Mekhalfia, James H, Rickard, Hazel, Denham, Lynda J, Partridge, Andreas, Plückthun, G Michael, Blackburn
Publikováno v:
Angewandte Chemie (International ed. in English). 41(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2c4317ffd30c4c5a661c0b18ff8927f
https://pubmed.ncbi.nlm.nih.gov/12491332
https://pubmed.ncbi.nlm.nih.gov/12491332
Autor:
Sandro Cesaro-Tadic, Abdelaziz Mekhalfia, G. Michael Blackburn, Andreas Plückthun, Lynda J. Partridge, Jason R. Betley, James H. Rickard, Hazel Denham
Publikováno v:
ResearcherID
In studies towards the generation and identification of catalytic antibodies with phosphate monoesterase activity, we have developed a direct selection approach for covalent modification of catalysts founded on mechanism-based phosphatase inhibitors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182b8eac56d7ebd0231a9aee5cc11609
https://doi.org/10.1002/1521-3773(20020503)41:9<1460::aid-anie1460>3.0.co
https://doi.org/10.1002/1521-3773(20020503)41:9<1460::aid-anie1460>3.0.co
Autor:
Abdelaziz Mekhalfia, Sandro Cesaro-Tadic, Jason R. Betley, Andreas Plückthun, James H. Rickard, Hazel Denham, Lynda J. Partridge, G. Michael Blackburn
Publikováno v:
Angewandte Chemie International Edition. 41:775
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eb4916493c05dae3a3e86fdb104c53f
https://doi.org/10.1002/1521-3773(20020301)41:5<775::aid-anie775>3.0.co
https://doi.org/10.1002/1521-3773(20020301)41:5<775::aid-anie775>3.0.co
Autor:
Jason R. Betley, G. Michael Blackburn
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 111:68-68
A series of hydroxymethylene and α,β-unsaturated aminophosphinic acids was prepared, modelled on the ‘exploded’ transition state proposed (Herschlag [1]) for the chemical hydrolysis of phosphate monoesters. They exhibit the dual utility of bein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0166af1c683e6d4512fbdedc94240644
https://doi.org/10.1080/10426509608054697
https://doi.org/10.1080/10426509608054697