Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Jason R. McCarthy"'
Autor:
Rachel S. Knipe, Md Nurunnabi, Clemens K. Probst, Jillian J. Spinney, Elizabeth Abe, Rajendran J. C. Bose, Khanh Ha, Amanda Logue, Trong Nguyen, Rachel Servis, Matthew Drummond, Alexis Haring, Patricia L. Brazee, Benjamin D. Medoff, Jason R. McCarthy
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L190-L198
Pulmonary fibrosis is characterized by the accumulation of myofibroblasts in the lung and progressive tissue scarring. Fibroblasts exist across a spectrum of states, from quiescence in health to activated myofibroblasts in the setting of injury. High
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a075ae371aab587a25d994a2b018da1f
https://doi.org/10.1152/ajplung.00086.2022
https://doi.org/10.1152/ajplung.00086.2022
Publikováno v:
Drug Discov Today
Cardiovascular disease (CVD) and its sequelae have long been the leading causes of death and disability in the developed world. Although mortality associated with CVD has been decreasing, due in large part to novel therapeutic options, the rate of de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02600aeb7d34685ab62339eb9bb43daa
https://doi.org/10.1016/j.drudis.2021.01.035
https://doi.org/10.1016/j.drudis.2021.01.035
Autor:
Jason R. McCarthy, Rajendran J.C. Bose, Intan Diana Mat Azmi, Yan Shan Loo, Thiagarajan Madheswaran
Publikováno v:
Drug Discovery Today. 26:902-915
Smart nanocarriers obtained from bacteria and viruses offer excellent biomimetic properties which has led to significant research into the creation of advanced biomimetic materials. Their versatile biomimicry has application as biosensors, biomedical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d673ed0e73b7681c94b52d92220de44
https://doi.org/10.1016/j.drudis.2020.12.017
https://doi.org/10.1016/j.drudis.2020.12.017
Autor:
Jason R. McCarthy, Yonghyun Choi, Nagendran Tharmalingam, Thiagarajan Madheswaran, Hansoo Park, Soo-Hong Lee, Ramasamy Paulmurugan, Rajendran J.C. Bose
Publikováno v:
International Journal of Nanomedicine. 15:8437-8449
Background Lipid polymer hybrid nanoparticles (LPHNPs) have been widely investigated in drug and gene delivery as well as in medical imaging. A knowledge of lipid-based surface engineering and its effects on how the physicochemical properties of LPHN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5394a6791c7aecdddf968ea057d058e7
https://doi.org/10.2147/ijn.s271850
https://doi.org/10.2147/ijn.s271850
Autor:
Sanjay Misra, Jie Cui, Harkamal S. Jhajj, Chase W. Kessinger, Jason R. McCarthy, Madeleine S. Grau, Peter Libby, Farouc A. Jaffer
Publikováno v:
Journal of the American Society of Nephrology. 31:931-945
BACKGROUND Arteriovenous fistulas placed surgically for dialysis vascular access have a high primary failure rate resulting from excessive inward remodeling, medial fibrosis, and thrombosis. No clinically established pharmacologic or perisurgical the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06f0743b970d971f44a026b6bb5c7363
https://doi.org/10.1681/asn.2019060612
https://doi.org/10.1681/asn.2019060612
Autor:
Chase W Kessinger, Jin Won Kim, Peter K Henke, Brian Thompson, Jason R McCarthy, Tetsuya Hara, Martin Sillesen, Ronan J P Margey, Peter Libby, Ralph Weissleder, Charles P Lin, Farouc A Jaffer
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0116621 (2015)
Despite anticoagulation therapy, up to one-half of patients with deep vein thrombosis (DVT) will develop the post-thrombotic syndrome (PTS). Improving the long-term outcome of DVT patients at risk for PTS will therefore require new approaches. Here w
Externí odkaz:
https://doaj.org/article/1426570cab754936b994b7507b74d44a
Autor:
Zehedina Khatun, Kang Moo Huh, Abu Zayed Md Badruddoza, Yong-kyu Lee, Jason R. McCarthy, Nurunnabi
Publikováno v:
ACS Biomaterials Science & Engineering. 5:1645-1660
When a therapeutic molecule is administered into a biological system, it faces numerous barriers on its way to the target site. While a portion of the administered dose can overcome these barriers, localize to the targeted site, and provide a therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8506e384b9272afb2b997e2282a6464
https://doi.org/10.1021/acsbiomaterials.8b01615
https://doi.org/10.1021/acsbiomaterials.8b01615
Autor:
Wenzhu Li, Jason R. McCarthy, Adam Mauskapf, Scott A. Hilderbrand, Xiaoxin Zheng, Makoto Orii, Khanh Ha, Yoichiro Kawamura, Chase W. Kessinger, Farouc A. Jaffer
Publikováno v:
ACS Sens
Platelets play a prominent role in multiple diseases, in particular arterial and venous thrombosis and also in atherosclerosis and cancer. To advance the in vivo study of the biological activity of this cell type from a basic experimental focus to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9100d833b55b4196ef02d96be9e457
https://europepmc.org/articles/PMC8767556/
https://europepmc.org/articles/PMC8767556/
Publikováno v:
Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XIII.
Activated platelets play a prominent role in multiple diseases, in particular arterial and venous thrombosis, as well as in atherosclerosis and cancer. More recent studies demonstrate further an important role for platelets in generating a permissive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::266b6d7421bc35235da06a7f65f832d3
https://doi.org/10.1117/12.2577254
https://doi.org/10.1117/12.2577254
Autor:
Jie Cui, Jason R. McCarthy, Chase W. Kessinger, Madeleine S. Grau, Peter Libby, Sanjay Misra, Harkamal S. Jhajj, Farouc A. Jaffer
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Arteriovenous fistulas placed surgically for dialysis vascular access have a high primary failure rate resulting from excessive inward remodeling, medial fibrosis, and thrombosis. No clinically established pharmacologic or perisurgical th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e3cefbe60ea16e53304cbc920b5458
https://pubmed.ncbi.nlm.nih.gov/32152232
https://pubmed.ncbi.nlm.nih.gov/32152232