Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jason R. Killough"'
Autor:
Upasana Parthasarathy, Yi Kuang, Gunjan Thakur, John D. Hogan, Thomas P. Wyche, James E. Norton, Jr., Jason R. Killough, Theodore R. Sana, Caroline Beakes, BaoJen Shyong, Rena N. Zhang, Dario A. Gutierrez, Michael Filbin, David C. Christiani, Alex G. Therien, Christopher H. Woelk, Cory H. White, Roberta Martinelli
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105948- (2023)
Summary: Sepsis is a life-threatening condition caused by a dysregulated host response to infection. Despite continued efforts to understand the pathophysiology of sepsis, no effective therapies are currently available. While singular components of t
Externí odkaz:
https://doaj.org/article/a7bebae0729f4859866504aea19e208c
Autor:
Jessica Neil, Caitlin Vestal Tibbetts, Kellie Marie Demock, Susan H. Smith, Christine Patricia Donahue, Jon D. Lenn, Javier Cote-Sierra, P. Shannon Pendergrast, Jason R. Killough, Adrian C. Williams, Marc B. Brown, Jean-Philippe Therrien, David Rubenstein
Publikováno v:
The Journal of investigative dermatology. 138(2)
It is generally recognized that only relatively small molecular weight (typically∼ 500 Da) drugs can effectively permeate through intact stratum corneum. Here, we challenge this orthodoxy using a 62-nucleotide (molecular weight = 20,395 Da) RNA-bas
Autor:
Paula Burmeister, Charles Wilson, Chunhua Wang, Scott D. Lewis, Thomas Green Mccauley, Markus Kurz, Anthony D. Keefe, P. Shannon Pendergrast, Jason R. Killough, Alicia Ferguson, Sharon T. Cload, Lillian R. Horwitz, Kristin Thompson, John L. Diener
Publikováno v:
Oligonucleotides. 16(4)
Aptamers are short oligonucleotides that fold into well-defined three-dimensional architectures thereby enabling specific binding to molecular targets such as proteins. To be successful as a novel therapeutic modality, it is important for aptamers to
Autor:
Scott D. Lewis, Joseph M. Fraone, Ankit Makim, John L. Diener, David Fontana, H. Nicholas Marsh, H. A. Daniel Lagasse, Claude R. Benedict, James Rottman, Ryan M. Boomer, Renta Hutabarat, Jason R. Killough, Larry Cai, Madaline Gilbert, Patricia G. Merlino, Thomas Green Mccauley
Publikováno v:
Blood. 108:3930-3930
Following coronary artery damage, von Willebrand Factor (vWF) multimers adhere to exposed collagen via the vWF A3 domain. Platelets passing through damaged vessels under the conditions of high shear force associated with stenosed arteries will adhere
Autor:
Paula E. Burmeister, Chunhua Wang, Jason R. Killough, Scott D. Lewis, Lillian R. Horwitz, Alicia Ferguson, Kristin M. Thompson, P. Shannon Pendergrast, Thomas G. McCauley, Markus Kurz, John Diener, Sharon T. Cload, Charles Wilson, Anthony D. Keefe
Publikováno v:
Oligonucleotides; Vol. 16 Issue 4, p337-351, 15p