Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Jason R McCarthy"'
Autor:
Chase W Kessinger, Jin Won Kim, Peter K Henke, Brian Thompson, Jason R McCarthy, Tetsuya Hara, Martin Sillesen, Ronan J P Margey, Peter Libby, Ralph Weissleder, Charles P Lin, Farouc A Jaffer
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0116621 (2015)
Despite anticoagulation therapy, up to one-half of patients with deep vein thrombosis (DVT) will develop the post-thrombotic syndrome (PTS). Improving the long-term outcome of DVT patients at risk for PTS will therefore require new approaches. Here w
Externí odkaz:
https://doaj.org/article/1426570cab754936b994b7507b74d44a
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e665 (2007)
Probes that allow site-specific protein labeling have become critical tools for visualizing biological processes.Here we used phage display to identify a novel peptide sequence with nanomolar affinity for near infrared (NIR) (benz)indolium fluorochro
Externí odkaz:
https://doaj.org/article/573a956b25f340cf8912a3bc916eb70b
Autor:
Rachel S. Knipe, Md Nurunnabi, Clemens K. Probst, Jillian J. Spinney, Elizabeth Abe, Rajendran J. C. Bose, Khanh Ha, Amanda Logue, Trong Nguyen, Rachel Servis, Matthew Drummond, Alexis Haring, Patricia L. Brazee, Benjamin D. Medoff, Jason R. McCarthy
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L190-L198
Pulmonary fibrosis is characterized by the accumulation of myofibroblasts in the lung and progressive tissue scarring. Fibroblasts exist across a spectrum of states, from quiescence in health to activated myofibroblasts in the setting of injury. High
Publikováno v:
Drug Discov Today
Cardiovascular disease (CVD) and its sequelae have long been the leading causes of death and disability in the developed world. Although mortality associated with CVD has been decreasing, due in large part to novel therapeutic options, the rate of de
Autor:
Jason R. McCarthy, Rajendran J.C. Bose, Intan Diana Mat Azmi, Yan Shan Loo, Thiagarajan Madheswaran
Publikováno v:
Drug Discovery Today. 26:902-915
Smart nanocarriers obtained from bacteria and viruses offer excellent biomimetic properties which has led to significant research into the creation of advanced biomimetic materials. Their versatile biomimicry has application as biosensors, biomedical
Autor:
Jason R. McCarthy, Yonghyun Choi, Nagendran Tharmalingam, Thiagarajan Madheswaran, Hansoo Park, Soo-Hong Lee, Ramasamy Paulmurugan, Rajendran J.C. Bose
Publikováno v:
International Journal of Nanomedicine. 15:8437-8449
Background Lipid polymer hybrid nanoparticles (LPHNPs) have been widely investigated in drug and gene delivery as well as in medical imaging. A knowledge of lipid-based surface engineering and its effects on how the physicochemical properties of LPHN
Autor:
Sanjay Misra, Jie Cui, Harkamal S. Jhajj, Chase W. Kessinger, Jason R. McCarthy, Madeleine S. Grau, Peter Libby, Farouc A. Jaffer
Publikováno v:
Journal of the American Society of Nephrology. 31:931-945
BACKGROUND Arteriovenous fistulas placed surgically for dialysis vascular access have a high primary failure rate resulting from excessive inward remodeling, medial fibrosis, and thrombosis. No clinically established pharmacologic or perisurgical the
Autor:
Wenzhu Li, Jason R. McCarthy, Adam Mauskapf, Scott A. Hilderbrand, Xiaoxin Zheng, Makoto Orii, Khanh Ha, Yoichiro Kawamura, Chase W. Kessinger, Farouc A. Jaffer
Publikováno v:
ACS Sens
Platelets play a prominent role in multiple diseases, in particular arterial and venous thrombosis and also in atherosclerosis and cancer. To advance the in vivo study of the biological activity of this cell type from a basic experimental focus to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9100d833b55b4196ef02d96be9e457
https://europepmc.org/articles/PMC8767556/
https://europepmc.org/articles/PMC8767556/
Autor:
Zehedina Khatun, Kang Moo Huh, Abu Zayed Md Badruddoza, Yong-kyu Lee, Jason R. McCarthy, Nurunnabi
Publikováno v:
ACS Biomaterials Science & Engineering. 5:1645-1660
When a therapeutic molecule is administered into a biological system, it faces numerous barriers on its way to the target site. While a portion of the administered dose can overcome these barriers, localize to the targeted site, and provide a therape
Autor:
Masanori Saito, Jeffry S. Nyman, Satoru Egawa, Samuel L. Posey, Deke M. Blum, Stephanie N. Moore-Lotridge, Jonathan G. Schoenecker, Masato Yuasa, J. Patton Robinette, Jason R. McCarthy, Heather A. Cole, Alexander A. Hysong, Atsushi Okawa, Courtney E. Baker, Michael A. Benvenuti
Publikováno v:
Clinical Reviews in Bone and Mineral Metabolism
Bone fractures create five problems that must be resolved: bleeding, risk of infection, hypoxia, disproportionate strain, and inability to bear weight. There have been enormous advancements in our understanding of the molecular mechanisms that resolv