Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jason R Goldsmith"'
Autor:
Jason R. Goldsmith, Nina Spitofsky, Ali Zamani, Ryan Hood, Amanda Boggs, Xinyuan Li, Mingyue Li, Elizabeth Reiner, Arshad Ayyaz, Zienab Etwebi, Ling Lu, Javier Rivera Guzman, Mayassa J. Bou-Dargham, Terry Cathoupolis, Hakon Hakonarson, Honghong Sun, Jeffrey L. Wrana, Michael V. Gonzalez, Youhai H. Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
The molecular mechanisms that regulate intestinal Clu+ revival stem cells (revSCs) and their niche to enable regeneration in response to injury are unclear. Here, the authors show that mice without the phospholipid transport protein, TNFAIP8, causes
Externí odkaz:
https://doaj.org/article/e9560ffe66084f55bbdf91c1bdc498c6
Publikováno v:
Cells, Vol 10, Iss 4, p 871 (2021)
The intestine is a highly proliferative dynamic environment that relies on constant self-renewal of the intestinal epithelium to maintain homeostasis. Tumor necrosis factor-alpha-induced protein 8 (TNFAIP8 or TIPE0) is a regulator of PI3K-mediated si
Externí odkaz:
https://doaj.org/article/310d4b0ab97f4d1dbdec254155e9219b
Autor:
Li Zhang, Xinyuan Li, Mingyue Li, Youhai H. Chen, Jason R. Goldsmith, Zienab Etwebi, Jiyeon Yu, Songlin Shi, Mayassa J. Bou-Dargham, Lin Wan, Honghong Sun, Ting Li, Ali Zamani
Publikováno v:
Oncogene
Cancer metastasis accounts for nearly 90% of all cancer deaths. Metastatic cancer progression requires both cancer cell migration to the site of the metastasis and subsequent proliferation after colonization. However, it has long been recognized that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f8b94a9293b5c7b9670a6053717947
https://doi.org/10.1038/s41388-021-02035-6
https://doi.org/10.1038/s41388-021-02035-6
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 1, Pp 146-159 (2013)
SUMMARY Beside their analgesic properties, opiates exert beneficial effects on the intestinal wound healing response. In this study, we investigated the role of μ-opioid receptor (MOR) signaling on the unfolded protein response (UPR) using a novel z
Externí odkaz:
https://doaj.org/article/d2290951713242d2949fc8d69ed4dc85
Autor:
Ting Li, Jason R. Goldsmith, Honghong Sun, Youhai H. Chen, Xinyuan Li, Emily Eiler, George Luo, Wei Wang
Publikováno v:
Mol Immunol
Genome-wide association studies have established that human REL is a susceptibility gene for lymphoid cancers and inflammatory diseases. REL is the hematopoietic member of the nuclear factor-κB (NF-κB) family and is frequently amplified in human ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a52fd43da607028b2a08d9fad5efff
https://doi.org/10.1016/j.molimm.2020.06.029
https://doi.org/10.1016/j.molimm.2020.06.029
Autor:
Ling Lu, Hakon Hakonarson, Youhai H. Chen, Javier Rivera Guzman, Elizabeth Reiner, Xinyuan Li, Zienab Etwebi, Michael Gonzalez, Ryan Hood, Ali Zamani, Mayassa J. Bou-Dargham, Jason R. Goldsmith, Honghong Sun, Jeffrey L. Wrana, Nina Spitofsky, Arshad Ayyaz, Terry Cathoupolis, Mingyue Li, Amanda E. Boggs
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Nature Communications
Nature Communications
The intestine is a highly dynamic environment that requires tight control of the various inputs to maintain homeostasis and allow for proper responses to injury. It was recently found that the stem cell niche and epithelium is regenerated after injur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0538db3607e35923d40dda4bea805d73
http://link.springer.com/article/10.1038/s41467-020-16379-2
http://link.springer.com/article/10.1038/s41467-020-16379-2
Autor:
Zienab Etwebi, Jason R Goldsmith, Mayassa Bou-Dargham, Yuhua Tian, Ryan Hood, Nina Spitofsky, Mingyue Li, Honghong Sun, Yunwei Lou, Suxia Liu, Christopher Lengner, Youhai H Chen
Publikováno v:
Inflamm Bowel Dis
Background Colorectal cancer (CRC) is the third leading cause of cancer in the United States, and inflammatory bowel disease patients have an increased risk of developing CRC due to chronic intestinal inflammation with it being the cause of death in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7f299521dc853c15a50709e94d058e
https://europepmc.org/articles/PMC9074867/
https://europepmc.org/articles/PMC9074867/
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1efe959cdfabff35ffb69c1a7fa7e7b9
https://doi.org/10.1096/fasebj.2021.35.s1.02598
https://doi.org/10.1096/fasebj.2021.35.s1.02598
Autor:
Chin-Nien Lee, Ting Li, Mei Lin, Songlin Shi, Xinyuan Li, Jason R. Goldsmith, Mingyue Li, Yunwei Lou, Amanda E. Boggs, Youhai H. Chen, Honghong Sun, Brigid L. Dorrity, Xu Chen, Ali Zamani, Wei Wang, Ning Li
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Lymphocytes are some of the most motile cells of vertebrates, constantly navigating through various organ systems. Their specific positioning in the body is delicately controlled by site-specific directional cues such as chemokines. While it has long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f094341a078c592cb999b2b1a6f7dc44
https://pubmed.ncbi.nlm.nih.gov/32313148
https://pubmed.ncbi.nlm.nih.gov/32313148
Autor:
Mei Lin, Youhai H. Chen, Svetlana Fayngerts, Thomas Porturas, Honghong Sun, Weidong Xie, Terry Cathopoulis, Ali Zamani, Jason R. Goldsmith, Anastassios Vourekas, Amanda E. Boggs, Zhaojun Wang
Publikováno v:
Nature immunology
The polarization of leukocytes toward chemoattractants is essential for the directed migration (chemotaxis) of leukocytes. How leukocytes acquire polarity after encountering chemical gradients is not well understood. We found here that leukocyte pola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d5e225957ff2d5003e494c09d99ed3
http://europepmc.org/articles/PMC5690821
http://europepmc.org/articles/PMC5690821