Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jason R Devlin"'
Autor:
Jason R Devlin, William Santus, Jorge Mendez, Wenjing Peng, Aiying Yu, Junyao Wang, Xiomarie Alejandro-Navarreto, Kaitlyn Kiernan, Manmeet Singh, Peilin Jiang, Yehia Mechref, Judith Behnsen
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010167 (2022)
Salmonella enterica serovar Typhimurium (S. Typhimurium) is one of the leading causes of food-borne illnesses worldwide. To colonize the gastrointestinal tract, S. Typhimurium produces multiple virulence factors that facilitate cellular invasion. Chi
Externí odkaz:
https://doaj.org/article/7c1ddd316bf94ab9ac64ab2938d17bfa
Autor:
Nishant K. Singh, Jesus A. Alonso, Jason R. Devlin, Grant L. J. Keller, George I. Gray, Adarsh K. Chiranjivi, Sara G. Foote, Lauren M. Landau, Alyssa G. Arbuiso, Laura I. Weiss, Aaron M. Rosenberg, Lance M. Hellman, Michael I. Nishimura, Brian M. Baker
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
MHC restriction depicts CD4+ T cell activation by MHC-II and CD8A+ by MHC-I, but rare T cells with mismatched MHC restriction have been reported. Here the authors use crystallography to describe features of such a mismatched TCR-MHC interaction and i
Externí odkaz:
https://doaj.org/article/0743243588da4db7b9427d68ad78e7b9
Autor:
William Santus, Amisha P. Rana, Jason R. Devlin, Kaitlyn A. Kiernan, Carol C. Jacob, Joshua Tjokrosurjo, David M. Underhill, Judith Behnsen
Publikováno v:
Nature Microbiology. 7:2025-2038
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a659434d62fd1e642f396ca4ec9da4cf
https://doi.org/10.1038/s41564-022-01267-w
https://doi.org/10.1038/s41564-022-01267-w
Autor:
Timothy P. Riley, Grant L. J. Keller, Angela R. Smith, Lauren M. Davancaze, Alyssa G. Arbuiso, Jason R. Devlin, Brian M. Baker
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The development of immunological therapies that incorporate peptide antigens presented to T cells by MHC proteins is a long sought-after goal, particularly for cancer, where mutated neoantigens are being explored as personalized cancer vaccines. Alth
Externí odkaz:
https://doaj.org/article/c4c877b0b1b949df9e3516b65879b8fd
Autor:
Jason R. Devlin, Judith Behnsen
Publikováno v:
Infection and Immunity.
It has been widely appreciated that numerous bacterial species express chitinases for the purpose of degrading environmental chitin. However, chitinases and chitin-binding proteins are also expressed by pathogenic bacterial species during infection e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a86947ba6c96ff3c2ad1342dd8bd822
https://doi.org/10.1128/iai.00549-22
https://doi.org/10.1128/iai.00549-22
Autor:
Brian M. Baker, George Coukos, David Gfeller, Jesus A. Alonso, Cory M. Ayres, Alexandre Harari, Jason R. Devlin, Craig W. Vander Kooi, Sara Bobisse, Grant L.J. Keller
Publikováno v:
Nat Chem Biol
T-cell recognition of peptides incorporating nonsynonymous mutations, or neoepitopes, is a cornerstone of tumor immunity and forms the basis of new immunotherapy approaches including personalized cancer vaccines. Yet as they are derived from self-pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a984286ffa4b62a101f266d419f401
https://doi.org/10.1038/s41589-020-0610-1
https://doi.org/10.1038/s41589-020-0610-1
Autor:
William, Santus, Amisha P, Rana, Jason R, Devlin, Kaitlyn A, Kiernan, Carol C, Jacob, Joshua, Tjokrosurjo, David M, Underhill, Judith, Behnsen
Publikováno v:
Nature microbiology. 7(12)
The fungal gut microbiota (mycobiota) has been implicated in diseases that disturb gut homeostasis, such as inflammatory bowel disease. However, little is known about functional relationships between bacteria and fungi in the gut during infectious co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b55f91d91d48735db6ecebc02d0f70b1
https://pubmed.ncbi.nlm.nih.gov/36411353
https://pubmed.ncbi.nlm.nih.gov/36411353
Autor:
Grant L.J. Keller, Jesus A. Alonso, Timothy P. Riley, Kendra C. Foley, Nishant K. Singh, Brian M. Baker, Lance M. Hellman, Craig W. Vander Kooi, Cory M. Ayres, Michael I. Nishimura, Jason R. Devlin, Yuting Zhang
Publikováno v:
Molecular Therapy. 27:300-313
T cell receptors (TCRs) have emerged as a new class of immunological therapeutics. However, though antigen specificity is a hallmark of adaptive immunity, TCRs themselves do not possess the high specificity of monoclonal antibodies. Although a necess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7a37434c6ee2c7a776772482ea1ddf
https://doi.org/10.1016/j.ymthe.2018.12.010
https://doi.org/10.1016/j.ymthe.2018.12.010
Publikováno v:
Infection and Immunity
The term “microbiota” invokes images of mucosal surfaces densely populated with bacteria. These surfaces and the luminal compartments they form indeed predominantly harbor bacteria.
The term “microbiota” invokes images of mucosal surface
The term “microbiota” invokes images of mucosal surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873d85ec6af38bb7c958d0a71d6f2ee2
https://doi.org/10.1128/iai.00648-20
https://doi.org/10.1128/iai.00648-20