Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Jason R, Swedlow"'
Autor:
Franz S Gruber, Anthony Richardson, Zoe C Johnston, Rachel Myles, Neil R Norcross, David P Day, Irene Georgiou, Laura Sesma-Sanz, Caroline Wilson, Kevin D Read, Sarah Martins da Silva, Christopher L R Barratt, Ian H Gilbert, Jason R Swedlow
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297666 (2024)
Male contraceptive options and infertility treatments are limited, and almost all innovation has been limited to updates to medically assisted reproduction protocols and methods. To accelerate the development of drugs that can either improve or inhib
Externí odkaz:
https://doaj.org/article/f2f5d29a721e4ad38c065b5e3404a1c2
Autor:
Rudolf Wittner, Petr Holub, Cecilia Mascia, Francesca Frexia, Heimo Müller, Markus Plass, Clare Allocca, Fay Betsou, Tony Burdett, Ibon Cancio, Adriane Chapman, Martin Chapman, Mélanie Courtot, Vasa Curcin, Johann Eder, Mark Elliot, Katrina Exter, Carole Goble, Martin Golebiewski, Bron Kisler, Andreas Kremer, Simone Leo, Sheng Lin‐Gibson, Anna Marsano, Marco Mattavelli, Josh Moore, Hiroki Nakae, Isabelle Perseil, Ayat Salman, James Sluka, Stian Soiland‐Reyes, Caterina Strambio‐De‐Castillia, Michael Sussman, Jason R. Swedlow, Kurt Zatloukal, Jörg Geiger
Publikováno v:
Learning Health Systems, Vol 8, Iss 1, Pp n/a-n/a (2024)
Abstract Open and practical exchange, dissemination, and reuse of specimens and data have become a fundamental requirement for life sciences research. The quality of the data obtained and thus the findings and knowledge derived is thus significantly
Externí odkaz:
https://doaj.org/article/b93ad8533a86445b9fd50163b1ed76f6
Autor:
Alexander J. Ropelewski, Megan A. Rizzo, Jason R. Swedlow, Jan Huisken, Pavel Osten, Neda Khanjani, Kurt Weiss, Vesselina Bakalov, Michelle Engle, Lauren Gridley, Michelle Krzyzanowski, Tom Madden, Deborah Maiese, Meisha Mandal, Justin Waterfield, David Williams, Carol M. Hamilton, Wayne Huggins
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-8 (2022)
Abstract Recent advances in fluorescence microscopy techniques and tissue clearing, labeling, and staining provide unprecedented opportunities to investigate brain structure and function. These experiments’ images make it possible to catalog brain
Externí odkaz:
https://doaj.org/article/3d9ee52d708f418a9656854eb7dbcc34
Autor:
Zehra F. Nizami
Publikováno v:
Microscopy and Microanalysis. 16:649-649
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c8c66595584ebc8d7e833d59601872d
https://doi.org/10.1017/s1431927610000310
https://doi.org/10.1017/s1431927610000310
Autor:
Franz S. Gruber, Anthony Richardson, Zoe C. Johnston, Rachel Myles, Neil Norcross, David Day, Irene Georgiou, Laura Sesma Sanz, Caroline Wilson, Kevin D. Read, Sarah Martins da Silva, Christopher L. R. Barratt, Ian H. Gilbert, Jason R. Swedlow
Male contraceptive options and infertility treatments are limited. To help overcome these limitations we established a small molecule library as a toolbox for assay development and screening campaigns using human spermatozoa. We have profiled all com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1f8a71fa8e5a4846798fbbccf07f3af
https://doi.org/10.1101/2023.05.02.539126
https://doi.org/10.1101/2023.05.02.539126
Autor:
Rudolf Wittner, Petr Holub, Cecilia Mascia, Francesca Frexia, Heimo Müller, Markus Plass, Clare Allocca, Fay Betsou, Tony Burdett, Ibon Cancio, Adriane Chapman, Martin Chapman, Mélanie Courtot, Vasa Curcin, Johann Eder, Mark Elliot, Katrina Exter, Carole Goble, Martin Golebiewski, Bron Kisler, Andreas Kremer, Simone Leo, Sheng Lin‐Gibson, Anna Marsano, Marco Mattavelli, Josh Moore, Hiroki Nakae, Isabelle Perseil, Ayat Salman, James Sluka, Stian Soiland‐Reyes, Caterina Strambio‐De‐Castillia, Michael Sussman, Jason R. Swedlow, Kurt Zatloukal, Jörg Geiger
Publikováno v:
Wittner, R, Holub, P, Mascia, C, Frexia, F, Müller, H, Plass, M, Allocca, C, Betsou, F, Burdett, T, Cancio, I, Chapman, A, Chapman, M, Courtot, M, Curcin, V, Eder, J, Elliot, M, Exter, K, Goble, C, Golebiewski, M, Kisler, B, Kremer, A, Leo, S, Lin-Gibson, S, Marsano, A, Mattavelli, M, Moore, J, Nakae, H, Perseil, I, Salman, A, Sluka, J, Soiland-Reyes, S, Strambio-De-Castillia, C, Sussman, M, Swedlow, J R, Zatloukal, K & Geiger, J 2023, ' Towards a common standard for data and specimen provenance in life sciences ', Learning Health Systems . https://doi.org/10.1002/lrh2.10365
The exchange of biological material and data has become an issue of major importance for research in biotechnology. At the same time, many reports indicate problems with quality, trustworthiness and reproducibility of research results, mainly due to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60687c03dab8edd3b984ca2ecbc6e67d
https://doi.org/10.1002/lrh2.10365
https://doi.org/10.1002/lrh2.10365
Autor:
Adam Ostrowski, Francesca R Cianfanelli, Michael Porter, Giuseppina Mariano, Julien Peltier, Jun Jie Wong, Jason R Swedlow, Matthias Trost, Sarah J Coulthurst
Publikováno v:
PLoS Pathogens, Vol 14, Iss 7, p e1007230 (2018)
The Type VI secretion system (T6SS) is widely used by bacterial pathogens as an effective weapon against bacterial competitors and is also deployed against host eukaryotic cells in some cases. It is a contractile nanomachine which delivers toxic effe
Externí odkaz:
https://doaj.org/article/259083db4d8149e3857f035d50388c1d
Autor:
Ardan Patwardhan, Robert Brandt, Sarah J Butcher, Lucy Collinson, David Gault, Kay Grünewald, Corey Hecksel, Juha T Huiskonen, Andrii Iudin, Martin L Jones, Paul K Korir, Abraham J Koster, Ingvar Lagerstedt, Catherine L Lawson, David Mastronarde, Matthew McCormick, Helen Parkinson, Peter B Rosenthal, Stephan Saalfeld, Helen R Saibil, Sirarat Sarntivijai, Irene Solanes Valero, Sriram Subramaniam, Jason R Swedlow, Ilinca Tudose, Martyn Winn, Gerard J Kleywegt
Publikováno v:
eLife, Vol 6 (2017)
The integration of cellular and molecular structural data is key to understanding the function of macromolecular assemblies and complexes in their in vivo context. Here we report on the outcomes of a workshop that discussed how to integrate structura
Externí odkaz:
https://doaj.org/article/894e26f1fe364e90b4d2256c2a6eedf1
Autor:
Katharina Schleicher, Michael Porter, Sara ten Have, Ramasubramanian Sundaramoorthy, Iain M. Porter, Jason R. Swedlow
Publikováno v:
Open Biology, Vol 7, Iss 11 (2017)
Regulation of protein phosphatase activity by endogenous protein inhibitors is an important mechanism to control protein phosphorylation in cells. We recently identified Biorientation defective 1 (Bod1) as a small protein inhibitor of protein phospha
Externí odkaz:
https://doaj.org/article/afbcbb801cf14923a997a6fbdf777098
Autor:
Neil R. Norcross, Irene Georgiou, Zoe C. Johnston, Franz S. Gruber, Jason R. Swedlow, Kevin D. Read, Christopher LR. Barratt, Ian H. Gilbert
Publikováno v:
European journal of medicinal chemistry. 243
There is a need for non-hormonal contraceptives. One area that needs further investigation is the development of male contraceptives. Comparatively little is understood about potential drug targets in men to achieve a reversible contraceptive effect.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ced93c8d835649047f8d729d5ad37cb
https://pubmed.ncbi.nlm.nih.gov/36087385
https://pubmed.ncbi.nlm.nih.gov/36087385