Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Jason R, Lees"'
Autor:
Balamurugan, Packialakshmi, Sharanpreet, Hira, Yuanyi, Feng, David W, Scott, Jason R, Lees, Xiaoming, Zhou
Publikováno v:
Cellular immunology. 382
Multiple sclerosis is believed to be triggered by the interplay between the environmental and genetic factors. In contrast to the Paleolithic diet, the modern Western diet is high in Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72e9c26503c835bc4886e63ff0dc5b65
https://pubmed.ncbi.nlm.nih.gov/36343517
https://pubmed.ncbi.nlm.nih.gov/36343517
Autor:
Balamurugan Packialakshmi, Sharanpreet Hira, Kateryna Lund, Ai-Hong Zhang, Julia Halterman, Yuanyi Feng, David W. Scott, Jason R. Lees, Xiaoming Zhou
Publikováno v:
Cellular immunology. 375
Multiple sclerosis disproportionally affects women. The present study was undertaken to determine whether NFAT5 contributed to the pathogenesis of experimental autoimmune encephalomyelitis (EAE), a model of multiple sclerosis, and if it did, whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd148428a5fa044b7957c6d03f425b09
https://pubmed.ncbi.nlm.nih.gov/35417812
https://pubmed.ncbi.nlm.nih.gov/35417812
Autor:
Balamurugan Packialakshmi, Sharanpreet Hira, Yuanyi Feng, David W. Scott, Jason R. Lees, Xiaoming Zhou
Publikováno v:
Cellular Immunology. 382:104637
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76ff6e756ef240509178757937d07d88
https://doi.org/10.1016/j.cellimm.2022.104637
https://doi.org/10.1016/j.cellimm.2022.104637
Autor:
Jason R. Lees
Publikováno v:
Cellular Immunology. 339:4-9
Autoimmune diseases are heterogeneous group of disorders that together represent an enormous societal and medical problem. CD4+ T cells have critical roles in the initiation and pathogenesis of autoimmune disease. As such, modulation of T cell activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b19712350182b7879bc5d876db6e6e
https://doi.org/10.1016/j.cellimm.2018.12.006
https://doi.org/10.1016/j.cellimm.2018.12.006
Autor:
Jason R. Lees
Publikováno v:
Cellular immunology. 357
Regulation of the adaptive immune response is critical for health. Regulatory activity can be found in multiple components of the immune system, however, the focus on particular components of the immune regulatory network has left many aspects of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a9dfa9a96daf403e66ff40871bdd70
https://pubmed.ncbi.nlm.nih.gov/32979764
https://pubmed.ncbi.nlm.nih.gov/32979764
Autor:
Ian A Cockburn, Yun-Chi Chen, Michael G Overstreet, Jason R Lees, Nico van Rooijen, Donna L Farber, Fidel Zavala
Publikováno v:
PLoS Pathogens, Vol 6, Iss 5, p e1000877 (2010)
Immunization with irradiated sporozoites is currently the most effective vaccination strategy against liver stages of malaria parasites, yet the mechanisms underpinning the success of this approach are unknown. Here we show that the complete developm
Externí odkaz:
https://doaj.org/article/1529fb508d934fd49006eb89a8e82342
Autor:
Armugam P. Mekala, Dallas Boodhoo, Jason R. Lees, Paul A. Antony, Cosmin Tegla, Irina G. Luzina, Vinh Q. Nguyen, Cornelia Cudrici, Alexandru Tatomir, Horea Rus, Tudor C. Badea, Violeta Rus
Publikováno v:
The Journal of Immunology. 198:3869-3877
Th17 cells play a critical role in autoimmune diseases, including multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis. Response gene to complement (RGC)-32 is a cell cycle regulator and a downstream target of TGF-β tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f08c5baeee227f96c5443eeaf8e433b
https://doi.org/10.4049/jimmunol.1602158
https://doi.org/10.4049/jimmunol.1602158
Autor:
Bodhraj Acharya, Shivaprasad H. Venkatesha, Jason R. Lees, Kamal D. Moudgil, Tambet Teesalu, Rakeshchandra R. Meka
Publikováno v:
Mol Cell Probes
Using phage peptide library screening, we identified peptide-encoding phages that selectively home to the inflamed central nervous system (CNS) of mice with experimental autoimmune encephalomyelitis (EAE), a model of human multiple sclerosis (MS). A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad6b649a68b7960f2844e167de243d7
https://doi.org/10.1016/j.mcp.2020.101530
https://doi.org/10.1016/j.mcp.2020.101530
Autor:
Kai W. Wucherpfennig, Ai-Hong Zhang, Yong Chan Kim, Jeongheon Yoon, William E. Culp, Jason R. Lees, David W. Scott
Publikováno v:
Journal of autoimmunity. 92
Expanded polyclonal T regulatory cells (Tregs) offer great promise for the treatment of immune-mediated diseases. Inhibition by Tregs is under the control of the T-cell receptor (TCR). Therefore, we created Tregs with defined antigen specificity, usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140e883fced6d6990fb88590ef5c4f8c
https://pubmed.ncbi.nlm.nih.gov/29857928
https://pubmed.ncbi.nlm.nih.gov/29857928
Autor:
Xin Li, Jason R. Lees
Publikováno v:
Immunology. 138:208-215
In region-specific forms of experimental autoimmune encephalomyelitis (EAE), lesion initiation is regulated by T-cell-produced interferon-γ (IFN-γ) resulting in spinal cord disease in the presence of IFN-γ and cerebellar disease in the absence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820f9b6a7e06cffb1693f630eacc5e03
https://doi.org/10.1111/imm.12029
https://doi.org/10.1111/imm.12029