Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jason Piper"'
Autor:
Pierre Cauchy, Sally R. James, Joaquin Zacarias-Cabeza, Anetta Ptasinska, Maria Rosaria Imperato, Salam A. Assi, Jason Piper, Martina Canestraro, Maarten Hoogenkamp, Manoj Raghavan, Justin Loke, Susanna Akiki, Samuel J. Clokie, Stephen J. Richards, David R. Westhead, Michael J. Griffiths, Sascha Ott, Constanze Bonifer, Peter N. Cockerill
Publikováno v:
Cell Reports, Vol 12, Iss 5, Pp 821-836 (2015)
Acute myeloid leukemia (AML) is characterized by recurrent mutations that affect the epigenetic regulatory machinery and signaling molecules, leading to a block in hematopoietic differentiation. Constitutive signaling from mutated growth factor recep
Externí odkaz:
https://doaj.org/article/890fdb6f789647a8a26cb2cb15a4e709
Autor:
Anetta Ptasinska, Salam A. Assi, Natalia Martinez-Soria, Maria Rosaria Imperato, Jason Piper, Pierre Cauchy, Anna Pickin, Sally R. James, Maarten Hoogenkamp, Dan Williamson, Mengchu Wu, Daniel G. Tenen, Sascha Ott, David R. Westhead, Peter N. Cockerill, Olaf Heidenreich, Constanze Bonifer
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1974-1988 (2014)
Oncogenic transcription factors such as RUNX1/ETO, which is generated by the chromosomal translocation t(8;21), subvert normal blood cell development by impairing differentiation and driving malignant self-renewal. Here, we use digital footprinting a
Externí odkaz:
https://doaj.org/article/1fe4d0303dc543039f5c3b1c928e5200
Autor:
Suzanne Brewerton, Ken Bloom, Zhen Xuan Yeo, Amalio Telenti, Jason Piper, J. Craig Venter, Tao Long, Richard H. Scheuermann, Chao Xie, Colleen Brady, Stephen R. Spellman, William H. Biggs, Sally Howard, Ewen F. Kirkness, Marie Wong, Cynthia Vierra-Green, Yaron Turpaz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 30
Significance Regulation of the human immune system is largely controlled by the HLA gene complex on chromosome 6 and is important in infectious disease immunity, graft rejection, autoimmunity, and cancer. HLA typing is traditionally performed by sero
Autor:
Jason Piper
Publikováno v:
Nursing and Residential Care. 20:104-106
HMRC is proposing a number of changes to tax compliance and administration law, with the consultation closing in March 2018. In this article, Jason Piper outlines both recent and proposed changes, and what they mean for care homes operating in the UK
Autor:
Jason Piper
Publikováno v:
Nursing and Residential Care. 19:164-166
Most small, independent homes will fall under the banner of small and medium-sized enterprises. In this article, Jason Piper outlines the timetable that these homes should be following to ensure the minimum upset at the end of the tax year
Autor:
Alena Harley, Barry W. Hicks, Chao Xie, Timothy T. Lu, Theodore M. Wong, Yaron Turpaz, Riccardo Sabatini, Wen-Yun Yang, Mingfu Zhu, Suzanne Brewerton, Seunghak Lee, Eun Yong Kang, Christopher J. Chang, Haibao Tang, M. Cyrus Maher, Jason Piper, Franz Josef Och, Amalio Telenti, Peter Garst, Christoph Lippert, Rhonda K. Roby, Kenneth Yocum, Victor Lavrenko, Axel Bernal, J. Craig Venter, Charlie W. H. Lee, Smriti Ramakrishnan, Okan Arikan
Prediction of human physical traits and demographic information from genomic data challenges privacy and data deidentification in personalized medicine. To explore the current capabilities of phenotype-based genomic identification, we applied whole-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b4e39454734858a2bec4f290b88762
https://europepmc.org/articles/PMC5617305/
https://europepmc.org/articles/PMC5617305/
Autor:
Jason Piper
Publikováno v:
Nursing and Residential Care. 17:463-465
Nobody likes a tax investigation – they're stressful, time-consuming and potentially expensive. The key, argues Jason Piper, is to avoid them in the first place. Here's how.
Autor:
Jason Piper
Publikováno v:
Nursing and Residential Care. 17:282-284
Real Time Information (RTI) and pensions auto-enrolment represent a huge shake-up for employee payroll. Low pay and high turnover in some parts of the care home sector can makes things even more complicated. Jason Piper looks for ways to ease the hea
Autor:
Jason Piper, Sascha Ott, Salam A. Assi, Christophe Ladroue, Pierre Cauchy, Constanze Bonifer, Peter N. Cockerill
Publikováno v:
BMC Genomics
Background The analysis of differential gene expression is a fundamental tool to relate gene regulation with specific biological processes. Differential binding of transcription factors (TFs) can drive differential gene expression. While DNase-seq da
Autor:
Sarah L, Bevington, Pierre, Cauchy, Jason, Piper, Elisabeth, Bertrand, Naveen, Lalli, Rebecca C, Jarvis, Liam Niall, Gilding, Sascha, Ott, Constanze, Bonifer, Peter N, Cockerill
Publikováno v:
The EMBO Journal
Immunological memory is a defining feature of vertebrate physiology, allowing rapid responses to repeat infections. However, the molecular mechanisms required for its establishment and maintenance remain poorly understood. Here, we demonstrated that