Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jason P. Torres"'
Autor:
Jason P. Torres, Alireza G. Senejani, Gauri Gaur, Michael Oldakowski, Krithika Murali, Eva Sapi
Publikováno v:
Antibiotics, Vol 9, Iss 9, p 528 (2020)
Borrelia burgdorferi, the causative agent of Lyme disease, has been recently shown to form biofilm structures in vitro and in vivo. Biofilms are tightly clustered microbes characterized as resistant aggregations that allow bacteria to withstand harsh
Externí odkaz:
https://doaj.org/article/f5a322862e3e411c97253003c8a0d373
Autor:
Eva Sapi, Rumanah S. Kasliwala, Hebo Ismail, Jason P. Torres, Michael Oldakowski, Sarah Markland, Gauri Gaur, Anthony Melillo, Klaus Eisendle, Kenneth B. Liegner, Jenny Libien, James E. Goldman
Publikováno v:
Antibiotics, Vol 8, Iss 4, p 183 (2019)
Whether Borrelia burgdorferi, the causative agent of Lyme disease, can persist for long periods in the human body has been a controversial question. The objective of this study was to see if we could find B. burgdorferi in a Lyme disease patient afte
Externí odkaz:
https://doaj.org/article/545968dd16514b61b294ed07727c8c5f
Publikováno v:
Antibiotics, Vol 6, Iss 4, p 31 (2017)
Lyme disease is a tick-borne, multi-systemic disease, caused by the bacterium Borrelia burgdorferi. Though antibiotics are used as a primary treatment, relapse often occurs after the discontinuation of antimicrobial agents. The reason for relapse rem
Externí odkaz:
https://doaj.org/article/ba20f3662d2e432caf9440722cb5683b
Autor:
Jason M. Torres, Vibe Nylander, Han Sun, Martijn van de Bunt, Damien J. Downes, Mark I. McCarthy, Jim R. Hughes, Anna L. Gloyn
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Background: Resolving causal genes for type 2 diabetes at loci implicated by genome-wide association studies (GWAS) requires integrating functional genomic data from relevant cell types. Chromatin features in endocrine cells of the pancreatic islet a
Externí odkaz:
https://doaj.org/article/887578fcac7042d7bd19c922142bef24
Autor:
Alvaro N. Barbeira, Scott P. Dickinson, Rodrigo Bonazzola, Jiamao Zheng, Heather E. Wheeler, Jason M. Torres, Eric S. Torstenson, Kaanan P. Shah, Tzintzuni Garcia, Todd L. Edwards, Eli A. Stahl, Laura M. Huckins, GTEx Consortium, Dan L. Nicolae, Nancy J. Cox, Hae Kyung Im
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-20 (2018)
Phenotypic variation and diseases are influenced by factors such as genetic variants and gene expression. Here, Barbeira et al. develop S-PrediXcan to compute PrediXcan results using summary data, and investigate the effects of gene expression variat
Externí odkaz:
https://doaj.org/article/74f1758878ad410698934b8de48e83e1
Autor:
Jason P. Torres, Bernhard Zelger, K. Gupta, Gauri Gaur, Katherine R. Filush, Anthony Melillo, K. Wawrzeniak, Eva Sapi
Publikováno v:
European Journal of Microbiology & Immunology, Vol 9, Iss 2, Pp 46-55 (2019)
European Journal of Microbiology & Immunology
European Journal of Microbiology & Immunology
Our research group has recently shown that Borrelia burgdorferi, the Lyme disease bacterium, is capable of forming biofilms in Borrelia-infected human skin lesions called Borrelia lymphocytoma (BL). Biofilm structures often contain multiple organisms
Autor:
Gauri Gaur, James E. Goldman, Jenny Libien, Jason P. Torres, Hebo Ismail, Anthony Melillo, Eva Sapi, Michael Oldakowski, Sarah Markland, Rumanah S. Kasliwala, Klaus Eisendle, Kenneth B. Liegner
Publikováno v:
Antibiotics, Vol 8, Iss 4, p 183 (2019)
Antibiotics
Volume 8
Issue 4
Antibiotics
Volume 8
Issue 4
Whether Borrelia burgdorferi, the causative agent of Lyme disease, can persist for long periods in the human body has been a controversial question. The objective of this study was to see if we could find B. burgdorferi in a Lyme disease patient afte
Autor:
Venkata Arun Timmaraju, Jason P. Torres, Kayla M. Socarras, Shafiq Shaikh, Priyanka A. S. Theophilus, Eva Sapi
Publikováno v:
Microbiology (Reading, England). 162(11)
The spirochaete bacterium Borrelia burgdorferisensu lato is the aetiologic agent of Lyme disease. Borrelia is transmitted to mammals through tick bite and is adapted to survive at tick and mammalian physiological temperatures. We have previously show
Publikováno v:
Antibiotics, Vol 6, Iss 4, p 31 (2017)
Antibiotics
Antibiotics; Volume 6; Issue 4; Pages: 31
Antibiotics
Antibiotics; Volume 6; Issue 4; Pages: 31
Lyme disease is a tick-borne, multi-systemic disease, caused by the bacterium Borrelia burgdorferi. Though antibiotics are used as a primary treatment, relapse often occurs after the discontinuation of antimicrobial agents. The reason for relapse rem
Autor:
Parsa Akbari, Olukayode A. Sosina, Jonas Bovijn, Karl Landheer, Jonas B. Nielsen, Minhee Kim, Senem Aykul, Tanima De, Mary E. Haas, George Hindy, Nan Lin, Ian R. Dinsmore, Jonathan Z. Luo, Stefanie Hectors, Benjamin Geraghty, Mary Germino, Lampros Panagis, Prodromos Parasoglou, Johnathon R. Walls, Gabor Halasz, Gurinder S. Atwal, Regeneron Genetics Center, DiscovEHR Collaboration, Marcus Jones, Michelle G. LeBlanc, Christopher D. Still, David J. Carey, Alice Giontella, Marju Orho-Melander, Jaime Berumen, Pablo Kuri-Morales, Jesus Alegre-Díaz, Jason M. Torres, Jonathan R. Emberson, Rory Collins, Daniel J. Rader, Brian Zambrowicz, Andrew J. Murphy, Suganthi Balasubramanian, John D. Overton, Jeffrey G. Reid, Alan R. Shuldiner, Michael Cantor, Goncalo R. Abecasis, Manuel A. R. Ferreira, Mark W. Sleeman, Viktoria Gusarova, Judith Altarejos, Charles Harris, Aris N. Economides, Vincent Idone, Katia Karalis, Giusy Della Gatta, Tooraj Mirshahi, George D. Yancopoulos, Olle Melander, Jonathan Marchini, Roberto Tapia-Conyer, Adam E. Locke, Aris Baras, Niek Verweij, Luca A. Lotta
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Fat distribution is associated with cardiometabolic disease, although it has been less well studied than overall obesity. In a multiancestry exome-sequencing study, the authors identified predicted loss-of-function mutations in INHBE associated with
Externí odkaz:
https://doaj.org/article/9f24eb7300be4033aaf87fbf13407526