Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jason P. Hannon"'
Publikováno v:
Drug Development Research. 59:23-29
We describe a new experimental animal model which mimics closely the bronchoconstrictor effects of adenosine in asthmatics. Brown Norway (BN) rats were sensitized to ovalbumin (OA). Subsequent challenge with OA induced a marked and selective airway h
Autor:
Pascal Dournaud, Jacques Epelbaum, Caroline Nunn, Marisa Aliprandi, Jean-Marie Billard, Patrick Dutar, Jason P. Hannon, D. Moneta, Cécile Viollet, A. S. Carlo, Annamaria Vezzani, Cristina Richichi, Dominique Fehlmann, Daniel Hoyer
Publikováno v:
European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2002, 16 (5), pp.843-849. ⟨10.1046/j.1460-9568.2002.02146.x⟩
European Journal of Neuroscience, Wiley, 2002, 16 (5), pp.843-849. ⟨10.1046/j.1460-9568.2002.02146.x⟩
We have investigated the role of somatostatin receptor subtypes sst 2 and sst 4 in limbic seizures and glutamate-mediated neurotransmission in mouse hippocampus. As compared to wild-type littermates, homozygous mice lacking sst 2 receptors showed a 5
Publikováno v:
British Journal of Pharmacology. 136:111-119
We have explored the effects of bacterial endotoxin (lipopolysaccharide; LPS) on the response of the airways of Brown Norway (BN) rats to adenosine. Comparisons have been drawn with the effects on responses to methacholine and 5-hydroxytryptamine. In
Publikováno v:
Pharmacology Biochemistry and Behavior. 71:533-554
Serotonin (5-hydroxytryptamine, 5-HT) is probably unique among the monoamines in that its effects are subserved by as many as 13 distinct heptahelical, G-protein-coupled receptors (GPCRs) and one (presumably a family of) ligand-gated ion channel(s).
Autor:
Cécile Viollet, Dominique Fehlmann, Jacques Epelbaum, Jason P. Hannon, C. Petrucci, Daniel Hoyer
Publikováno v:
Neuropharmacology. 42:396-413
The peptide hormone/neurotransmitter somatostatin (somatotropin release inhibiting factor; SRIF) and its receptors (sst(1)-sst(5)) appear to regulate many physiological functions in the CNS. Semi-quantitative analysis of the densities of mRNA express
Autor:
I Williams, Lazzaro Mazzoni, John R. Fozard, Colin Howes, Jason P. Hannon, Cedric Wolber, Bruno Tigani
Publikováno v:
British Journal of Pharmacology. 135:685-696
The bronchoconstrictor response to adenosine is markedly and selectively increased following ovalbumin (OA) challenge in actively sensitized, Brown Norway rats. We present a pharmacological analysis of the receptor mediating this response. Like adeno
Autor:
Ian Lewis, Konstanze Hurth, Barbara Stolz, Troxler Thomas J, Jason P. Hannon, Christians Bruns, Daniel Hoyer, Caroline Nunn, Gisbert Weckbecker
Publikováno v:
Journal of Molecular Neuroscience. 18:15-28
Somatostatin (SRIF, somatotropin release inhibiting factor), discovered for its inhibitory action on growth hormone (GH) secretion from pituitary, is an abundant neuropeptide. Two forms, SRIF14 and SRIF28 exist. Recently, a second family of peptides
Publikováno v:
British Journal of Pharmacology. 132:1509-1523
We have explored the role of allergen sensitization and challenge in defining the response of the airways of the Brown Norway (BN) rat to adenosine. In naive animals or in rats sensitized to ovalbumin (OA) adenosine induced only weak bronchoconstrict
Publikováno v:
Drug Development Research. 43:214-224
The aims of this study were to characterize the adenosine receptor subtype mediating inhibition of superoxide anion generation induced by N-formyl-methionyl-leucylphenylalanine (fMLP) in human neutrophils and to test the hypothesis that adenosine 3':
Autor:
Jason P. Hannon, Daniel Hoyer
Publikováno v:
Behavioural brain research. 195(1)
Serotonin (5-hydroxytryptamine; 5-HT) is a monoamine neurotransmitter whose effects are mediated by at least 13 distinct G protein-coupled receptors (GPCRs) of the type A family which includes the monoamine receptors and a combination of ligand-gated