Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jason P. Hafler"'
Autor:
Vincent Plagnol, Joanna M M Howson, Deborah J Smyth, Neil Walker, Jason P Hafler, Chris Wallace, Helen Stevens, Laura Jackson, Matthew J Simmonds, Type 1 Diabetes Genetics Consortium, Polly J Bingley, Stephen C Gough, John A Todd
Publikováno v:
PLoS Genetics, Vol 7, Iss 8, p e1002216 (2011)
The genetic basis of autoantibody production is largely unknown outside of associations located in the major histocompatibility complex (MHC) human leukocyte antigen (HLA) region. The aim of this study is the discovery of new genetic associations wit
Externí odkaz:
https://doaj.org/article/476544fd02664068abcb4c5a0a51170c
Autor:
Simon Duley, Gillian Coleman, Barry C. Healy, Vincent Plagnol, Jane Worthington, Anne Hinks, Stephen C. L. Gough, Jason D. Cooper, Neil Walker, John A. Todd, Jason P. Hafler, Joanna M. M. Howson, Matthew J. Simmonds, M Maisuria, Linda S. Wicker, Helen Stevens, Vijay K. Kuchroo, Lisa M. Maier
Genome-wide association (GWA) studies provide insight into multigenic diseases through the identification of susceptibility genes and etiological pathways. In addition, identification of shared variants among autoimmune disorders provides insight int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007bbf9baed8eb5f659f35c3ee20e8a8
https://doi.org/10.1038/gene.2008.82
https://doi.org/10.1038/gene.2008.82
Autor:
Boel Brynedal, Steven D. Levin, Arlene H. Sharpe, Nasim Kassam, Silvia Spoerl, Vijay K. Kuchroo, Nicole Joller, Jason P. Hafler
Publikováno v:
The Journal of Immunology. 186:1338-1342
Costimulatory molecules regulate the functional outcome of T cell activation, and disturbance of the balance between activating and inhibitory signals results in increased susceptibility to infection or the induction of autoimmunity. Similar to the w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc9547329737b64416731134eecc2bb
https://doi.org/10.4049/jimmunol.1003081
https://doi.org/10.4049/jimmunol.1003081
Autor:
Sydney S. Cash, David A. Schoenfeld, Karen L. Furie, Patricia D. Scripko, Jason P. Hafler, Ona Wu, John R. Sims, David M. Greer, Jingyun Yang
Publikováno v:
Resuscitation. 84(11)
To build new algorithms for prognostication of comatose cardiac arrest patients using clinical examination, and investigate whether therapeutic hypothermia influences the value of the clinical examination.From 2000 to 2007, 500 consecutive patients i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b840403f3134841cc14f381365616d
https://pubmed.ncbi.nlm.nih.gov/23954666
https://pubmed.ncbi.nlm.nih.gov/23954666
Autor:
John R. Sims, Karen L. Furie, Ona Wu, David M. Greer, Jason P. Hafler, Ronan Kilbride, David A. Schoenfeld, Sydney S. Cash, Jingyun Yang, Patricia D. Scripko
Publikováno v:
Critical care medicine. 40(4)
Objectives: Determine the utility of the neurologic examination in comatose patients from nontraumatic causes in the modern era. Design: Prospective observational study. Setting: Single academic medical center. Patients: Data from 500 patients in non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a455a4963f5b762e4413208a4ea23c03
https://pubmed.ncbi.nlm.nih.gov/22425838
https://pubmed.ncbi.nlm.nih.gov/22425838
Autor:
Jason P. Hafler, Sarah F. Field, David Clayton, Neil Walker, Ellen C. Adlem, Meeta Maisuria, Adrian Vella, Stephen C. L. Gough, Jennie H M Yang, Helen Schuilenburg, David B. Dunger, Jeffrey S. Szeszko, Sergey Nejentsev, Nigel R. Ovington, Linda S. Wicker, William Meadows, Deborah J. Smyth, Gillian Coleman, Barry C. Healy, Sarah Nutland, Matthew J. Simmonds, Kate Downes, John A. Todd, Alex C. Lam, Lauren R. Zeitels, H. T. Leung, Oliver S. Burren, Chris Wallace, Felicity Payne, Constantin Ionescu-Tirgoviste, Jason D. Cooper, Luc J. Smink, Helen Stevens, Rebecca Bailey, Joanna M. M. Howson, James E. Allen, Vincent Plagnol, Cristian Guja, Joanne M. Heward, Christopher E. Lowe
Publikováno v:
Nature genetics. 39(7)
The Wellcome Trust Case Control Consortium (WTCCC) primary genome-wide association (GWA) scan1 on seven diseases, including the multifactorial, autoimmune disease, type 1 diabetes (T1D), shows significant association (P < 5 × 10−7 between T1D and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c29e98ee0d782068bc8956f1a895f6
http://ora.ox.ac.uk/objects/uuid:48dfb9e0-8e33-4d5c-8f5a-57777afdc468
http://ora.ox.ac.uk/objects/uuid:48dfb9e0-8e33-4d5c-8f5a-57777afdc468
Autor:
Helen Stevens, Vincent Plagnol, John A. Todd, Jason P. Hafler, Linda S. Wicker, Helen Schuilenburg, Neil Walker, Joanna M. M. Howson
Publikováno v:
Clinical Immunology. 131:S94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ecba0065334af8ef9835f58f623fe05
https://doi.org/10.1016/j.clim.2009.03.273
https://doi.org/10.1016/j.clim.2009.03.273