Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Jason P. Gleghorn"'
Autor:
Rachel E. Young, Katherine M. Nelson, Samuel I. Hofbauer, Tara Vijayakumar, Mohamad-Gabriel Alameh, Drew Weissman, Charalampos Papachristou, Jason P. Gleghorn, Rachel S. Riley
Publikováno v:
Bioactive Materials, Vol 34, Iss , Pp 125-137 (2024)
Ionizable lipid nanoparticles (LNPs) have gained attention as mRNA delivery platforms for vaccination against COVID-19 and for protein replacement therapies. LNPs enhance mRNA stability, circulation time, cellular uptake, and preferential delivery to
Externí odkaz:
https://doaj.org/article/030cc556d30340f79b8eba32bbbbe63c
Publikováno v:
Biology Open, Vol 11, Iss 9 (2022)
During airway branching morphogenesis, focal regions of FGF-10 expression in the pulmonary mesenchyme are thought to provide a local guidance cue, which promotes chemotactically the directional outgrowth of the airway epithelium. Here, however, we sh
Externí odkaz:
https://doaj.org/article/e180294b5da746b7a0987b5919ccaa7c
Autor:
Catherine S. Millar‐Haskell, John L. Sperduto, John H. Slater, Colin Thorpe, Jason P. Gleghorn
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 7, Pp n/a-n/a (2022)
Abstract Quiescin sulfhydryl oxidase 1 (QSOX1) is a disulphide bond generating catalyst that is overexpressed in solid tumours. Expression of QSOX1 is linked to cancer cell invasion, tumour grade, and aberrant extracellular matrix (ECM) protein depos
Externí odkaz:
https://doaj.org/article/0a5fb959be3643e099e9398cea044c30
Autor:
Oluyinka O. Olutoye II, Walker D. Short, Jamie Gilley, J. D. Hammond II, Michael A. Belfort, Timothy C. Lee, Alice King, Jimmy Espinoza, Luc Joyeux, Krithika Lingappan, Jason P. Gleghorn, Sundeep G. Keswani
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Congenital diaphragmatic hernia (CDH) is a complex disease associated with pulmonary hypoplasia and pulmonary hypertension. Great strides have been made in our ability to care for CDH patients, specifically in the prenatal improvement of lung volume
Externí odkaz:
https://doaj.org/article/f3e4f355d8364582a2647dc7387b32b0
Autor:
Alice E. Stanton, Katharine Goodwin, Aswin Sundarakrishnan, Jacob M. Jaslove, Jason P. Gleghorn, Amira L. Pavlovich, Celeste M. Nelson
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mechanical forces are increasingly recognized as important determinants of cell and tissue phenotype and also appear to play a critical role in organ development. During the fetal stages of lung morphogenesis, the pressure of the fluid within the lum
Externí odkaz:
https://doaj.org/article/3c30d800ab4e4f2ca162659a19cca9ae
Publikováno v:
MethodsX, Vol 6, Iss , Pp 1907-1918 (2019)
One of the largest issues facing the field of tissue engineering is scaling due to tissue necrosis as a result of a lack of vascularization. We have developed an accessible method for generating large scale vascular networks of arbitrary geometries t
Externí odkaz:
https://doaj.org/article/763b3f88d1d3458b8898d1972ee42d2d
Autor:
Joshua T. Morgan, Alan K. Robbins, Abigail B. Mateson, Kazuki Sawamoto, Shunji Tomatsu, Dione R. Gray, Jason P. Gleghorn, Julia Spencer Barthold
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Background: The process of testicular descent requires androgen and insulin-like 3, hormones secreted by fetal Leydig cells. Knowledge concerning distinct and common functions of these hormones in regulating development of the fetal gubernaculum rema
Externí odkaz:
https://doaj.org/article/7ea62aef21244721bb55f93c83c4e021
Autor:
Daniel Tzou, James W. Spurlin, Amira L. Pavlovich, Carolyn R. Stewart, Jason P. Gleghorn, Celeste M. Nelson
Publikováno v:
EvoDevo, Vol 7, Iss 1, Pp 1-7 (2016)
Abstract Background New branches within the embryonic chicken lung form via apical constriction, in which epithelial cells in the primary bronchus become trapezoidal in shape. These branches form at precise locations along the primary bronchus that s
Externí odkaz:
https://doaj.org/article/6fd5c2029a5847a2baac2a54f74164db
Autor:
Brian J. Kirby, Mona Jodari, Matthew S. Loftus, Gunjan Gakhar, Erica D. Pratt, Chantal Chanel-Vos, Jason P. Gleghorn, Steven M. Santana, He Liu, James P. Smith, Vicente N. Navarro, Scott T. Tagawa, Neil H. Bander, David M. Nanus, Paraskevi Giannakakou
Publikováno v:
PLoS ONE, Vol 7, Iss 7 (2012)
Externí odkaz:
https://doaj.org/article/f394fc18cbe14a8faa0c190cfac11b41
Autor:
Rachel M. Gilbert, Jason P. Gleghorn
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L456-L467
Congenital diaphragmatic hernia (CDH) is a developmental disorder that results in incomplete diaphragm formation, pulmonary hypoplasia, and pulmonary hypertension. Although a variety of genes have been linked to its etiology, CDH is not a monogenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c315911b35f02a5dc5c41ab9d1b4d6bd
https://doi.org/10.1152/ajplung.00349.2022
https://doi.org/10.1152/ajplung.00349.2022