Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jason P. Fernandes"'
Autor:
Brienne A. McKenzie, Jason P. Fernandes, Matthew A. L. Doan, Laura M. Schmitt, William G. Branton, Christopher Power
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-25 (2020)
Abstract Background Pyroptosis is a type of proinflammatory regulated cell death (RCD) in which caspase-1 proteolytically cleaves gasdermin D (GSDMD) to yield a cytotoxic pore-forming protein. Recent studies have suggested that additional cell death
Externí odkaz:
https://doaj.org/article/691b8686e7984ecbb15161b3bf767202
Autor:
Maliheh Safari, Bhargavi Jayaraman, Shumin Yang, Cynthia Smith, Jason D Fernandes, Alan D Frankel
Publikováno v:
eLife, Vol 11 (2022)
Overlapping coding regions balance selective forces between multiple genes. One possible division of nucleotide sequence is that the predominant selective force on a particular nucleotide can be attributed to just one gene. While this arrangement has
Externí odkaz:
https://doaj.org/article/c04a18a42a1f41d393f4480b04eab8d0
Autor:
Jason D. Fernandes, Armando Zamudio-Hurtado, Hiram Clawson, W. James Kent, David Haussler, Sofie R. Salama, Maximilian Haeussler
Publikováno v:
Mobile DNA, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract Background Nearly half the human genome consists of repeat elements, most of which are retrotransposons, and many of which play important biological roles. However repeat elements pose several unique challenges to current bioinformatic analy
Externí odkaz:
https://doaj.org/article/57d4074818574439ab6825cf48f69a28
Autor:
William G, Branton, Jason P, Fernandes, Nazanin, Mohammadzadeh, Mathew A L, Doan, Jon D, Laman, Benjamin B, Gelman, Zahra, Fagrouch, Ivanela, Kondova, Petra, Mooij, Gerrit, Koopman, Christopher, Power
Publikováno v:
Brain, Behavior, and Immunity, 107, 110-123. ACADEMIC PRESS INC ELSEVIER SCIENCE
Background: Systemic inflammation accompanies HIV-1 infection, resulting in microbial translocation from different tissues. We investigated interactions between lentivirus infections, neuroinflammation and microbial molecule presence in the brain. Me
Autor:
Jason D Fernandes, Sarvenaz Sarabipour, Christopher T Smith, Natalie M Niemi, Nafisa M Jadavji, Ariangela J Kozik, Alex S Holehouse, Vikas Pejaver, Orsolya Symmons, Alexandre W Bisson Filho, Amanda Haage
Publikováno v:
eLife, Vol 9 (2020)
Many postdoctoral researchers apply for faculty positions knowing relatively little about the hiring process or what is needed to secure a job offer. To address this lack of knowledge about the hiring process we conducted a survey of applicants for f
Externí odkaz:
https://doaj.org/article/7d3dbae4604a433d99d85fbf4f0d4800
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186823 (2017)
HIV infection causes a profound depletion of gut derived Th17 cells, contributing to loss of mucosal barrier function and an increase in microbial translocation, thus driving systemic immune activation. Despite normalization of circulating CD4+ T cel
Externí odkaz:
https://doaj.org/article/b14cae65b3ae453db6537a1cbb3a8b8c
Autor:
Jason Keith Fernandes
Publikováno v:
Ler História, Vol 58, Pp 9-25 (2010)
Afonso Mexia, was one of the founding figures of the Estado da India. This essay uses a contemporary reference to Mexia, by the Association of the Components of Comunidades, to draw links between the colonial past and postcolonial present, displaying
Externí odkaz:
https://doaj.org/article/24d8a57adfad4126a3c09e4e2b1bff0c
Autor:
Jason P Fernandes, Matthew A. L. Doan, Laura M. Schmitt, William G. Branton, Brienne A. McKenzie, Christopher Power
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-25 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Pyroptosis is a type of proinflammatory regulated cell death (RCD) in which caspase-1 proteolytically cleaves gasdermin D (GSDMD) to yield a cytotoxic pore-forming protein. Recent studies have suggested that additional cell death pathways
Autor:
Leina B. Saito, Laura M. Schmitt, Frank Wuest, Melinda Wuest, Maria Chiara Monaco, Matthew A. L. Doan, Jason P Fernandes, William G. Branton, Christopher Power, Mackenzie J Smith, Eugene O. Major
Publikováno v:
GliaREFERENCES. 69(1)
Inflammatory demyelination and axonal injury in the central nervous system (CNS) are cardinal features of progressive multiple sclerosis (MS), and linked to activated brain macrophage-like cells (BMCs) including resident microglia and trafficking mac
Autor:
Patricia A. Chen, Sarah Haeflinger, Maya Shmulevitz, Jason P Fernandes, Mary M. Hitt, Isabelle Bernard, Heather E. Eaton, Francisca Cristi
Publikováno v:
Journal of Virology. 93
Reovirus is undergoing clinical testing as an oncolytic therapy for breast cancer. Given that reovirus naturally evolved to thrive in enteric environments, we sought to better understand how breast tumor microenvironments impinge on reovirus infectio