Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jason P. Burdick"'
Autor:
Daniel C. Stewart, Becky K. Brisson, Bassil Dekky, Ashton C. Berger, William Yen, Elizabeth A. Mauldin, Claudia Loebel, Deborah Gillette, Charles-Antoine Assenmacher, Corisa Quincey, Darko Stefanovski, Massimo Cristofanilli, Edna Cukierman, Jason A. Burdick, Virginia F. Borges, Susan W. Volk
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Collagen plays a critical role in regulating breast cancer progression and therapeutic resistance. An improved understanding of both the features and drivers of tumor-permissive and -restrictive collagen matrices are critical to improve prog
Externí odkaz:
https://doaj.org/article/1f8570802070429fb59316d40cdbc510
Autor:
Selen Uman, Noah Weingarten, Mark Helmers, Amit Iyengar, Karen L. Xu, Kendra Worthington, Danika Meldrum, Jessica Dominic, Sara Guevara‐Plunkett, Alexis Schiazza, Pavan Atluri, Jason A. Burdick
Publikováno v:
Advanced NanoBiomed Research, Vol 4, Iss 11, Pp n/a-n/a (2024)
Extracellular vesicles (EVs) are gaining interest in regenerative medicine and biomaterials have been shown to extend EV bioavailability following delivery. Herein, the labeling of both hydrogels and EVs is reported to better understand hydrogel desi
Externí odkaz:
https://doaj.org/article/b439ab233ae54a12a026cc880e11873b
Autor:
Karen L. Xu, Nikolas Di Caprio, Hooman Fallahi, Mohammad Dehghany, Matthew D. Davidson, Lorielle Laforest, Brian C. H. Cheung, Yuqi Zhang, Mingming Wu, Vivek Shenoy, Lin Han, Robert L. Mauck, Jason A. Burdick
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cell migration is critical for tissue development and regeneration but requires extracellular environments that are conducive to motion. Cells may actively generate migratory routes in vivo by degrading or remodeling their environments or in
Externí odkaz:
https://doaj.org/article/727837455afe4513b4b5fd77bc79849e
Autor:
Andrea Schwab, Marinus A. Wesdorp, Jietao Xu, Florencia Abinzano, Claudia Loebel, Marc Falandt, Riccardo Levato, David Eglin, Roberto Narcisi, Martin J. Stoddart, Jos Malda, Jason A. Burdick, Matteo D'Este, Gerjo J.V.M. van Osch
Publikováno v:
Journal of Orthopaedic Translation, Vol 41, Iss , Pp 42-53 (2023)
Background: The use of acellular hydrogels to repair osteochondral defects requires cells to first invade the biomaterial and then to deposit extracellular matrix for tissue regeneration. Due to the diverse physicochemical properties of engineered hy
Externí odkaz:
https://doaj.org/article/1d4921330fa04c77aba174a7f37f6f2f
Autor:
Matthew Fainor, Brianna S. Orozco, Victoria G. Muir, Sonal Mahindroo, Sachin Gupta, Robert L. Mauck, Jason A. Burdick, Harvey E. Smith, Sarah E. Gullbrand
Publikováno v:
JOR Spine, Vol 6, Iss 4, Pp n/a-n/a (2023)
Abstract Background Vertebral endplate sclerosis and facet osteoarthritis have been documented in animals and humans. However, it is unclear how these adjacent pathologies engage in crosstalk with the intervertebral disc. This study sought to elucida
Externí odkaz:
https://doaj.org/article/abebc0e9758c40a7802f05139482a46d
Influence of Microgel and Interstitial Matrix Compositions on Granular Hydrogel Composite Properties
Autor:
Victoria G. Muir, Shoshana Weintraub, Abhishek P. Dhand, Hooman Fallahi, Lin Han, Jason A. Burdick
Publikováno v:
Advanced Science, Vol 10, Iss 10, Pp n/a-n/a (2023)
Abstract Granular hydrogels are an emerging class of biomaterials formed by jamming hydrogel microparticles (i.e., microgels). These materials have many advantageous properties that can be tailored through microgel design and extent of packing. To en
Externí odkaz:
https://doaj.org/article/1b52f2cfa5ea472ba16c84f1cff2acaa
Autor:
Boguang Yang, Kongchang Wei, Claudia Loebel, Kunyu Zhang, Qian Feng, Rui Li, Siu Hong Dexter Wong, Xiayi Xu, Chunhon Lau, Xiaoyu Chen, Pengchao Zhao, Chao Yin, Jason A. Burdick, Yi Wang, Liming Bian
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
3D culture systems can provide critical insights into cellular behaviour. Here, the authors study the binding timescale of dynamic crosslinks and the conjugation stability of cell-adhesive ligands in cell–hydrogel network interactions to evaluate t
Externí odkaz:
https://doaj.org/article/a5253e196b884f9e8779742f7f16765a
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Cellular models are needed to study disease in vitro and to screen drugs for toxicity and efficacy. Here the authors develop a bioprinting approach to transfer spheroids into self-healing support hydrogels at high resolution, which enables their patt
Externí odkaz:
https://doaj.org/article/c3e8be08fce540e59149aea73ed06887
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract 3D bioprinting is a promising approach for the repair of cartilage tissue after damage due to injury or disease; however, the design of 3D printed scaffolds has been limited by the availability of bioinks with requisite printability, cytocom
Externí odkaz:
https://doaj.org/article/8f642da163654c7bb22463da110983c6
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102475- (2021)
Summary: Recent engineering technologies have transformed traditional perspectives of cancer to include the important role of the extracellular matrix (ECM) in recapitulating the malignant behaviors of cancer cells. Novel biomaterials and imaging tec
Externí odkaz:
https://doaj.org/article/6d140da6052a473d85f03daa04a26565