Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Jason P Weick"'
Autor:
Máté Fischer, Amber Zimmerman, Eric Zhang, Joseph Kolis, Ashley Dickey, Mary K Burdette, Praveen Chander, Stephen H Foulger, Jonathan L Brigman, Jason P Weick
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0276819 (2023)
Due to increasing advances in their manufacture and functionalization, nanoparticle-based systems have become a popular tool for in vivo drug delivery and biodetection. Recently, scintillating nanoparticles such as yttrium orthosilicate doped with ce
Externí odkaz:
https://doaj.org/article/c9f63c14e4f04d59b935ad1debe325aa
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230026 (2020)
Pathological accumulation of microtubule associated protein tau in neurons is a major neuropathological hallmark of Alzheimer's disease (AD) and related tauopathies. Several attempts have been made to promote clearance of pathological tau (p-Tau) fro
Externí odkaz:
https://doaj.org/article/7cd30d21b32447aea19b7e30d252aaf8
Publikováno v:
Stem Cell Reports, Vol 9, Iss 5, Pp 1463-1476 (2017)
Summary: Default differentiation of human pluripotent stem cells has been promoted as a model of cortical development. In this study, a developmental transcriptome analysis of default-differentiated hPSNs revealed a gene expression program resembling
Externí odkaz:
https://doaj.org/article/f4282cca3f96490a8ecd83f9557c09b7
Autor:
Jason P. Weick
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Stem cell-derived neurons from various source materials present unique model systems to examine the fundamental properties of central nervous system (CNS) development as well as the molecular underpinnings of disease phenotypes. In order to more accu
Externí odkaz:
https://doaj.org/article/1d0e09a2a5d548cd894406843d6f2415
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Externí odkaz:
https://doaj.org/article/d93706bda5fa47339c96a60008ad16b8
Autor:
Brian A. Rodriguez, Jason P. Weick, Michela Dell'Orco, Jasmin Lalonde, Nikolaos Mellios, Alexander Hafez, Begum Alural, Jonathan L. Brigman, Nora I. Perrone-Bizzozero, Brigham J. Hartley, Praveen Chander, Evelyn Lozano, Kristen J. Brennand, Amber Zimmerman, Stephen J. Haggarty, Maree J. Webster, Roy H. Perlis, Stephen K. Amoah
Publikováno v:
Molecular Psychiatry
Although circular RNAs (circRNAs) are enriched in the mammalian brain, very little is known about their potential involvement in brain function and psychiatric disease. Here, we show that circHomer1a, a neuronal-enriched circRNA abundantly expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86030582e56d72d3704683a08389dd65
https://doi.org/10.1038/s41380-020-0653-4
https://doi.org/10.1038/s41380-020-0653-4
Autor:
Jason P. Weick, Praveen Chander, Stephen K. Amoah, Brian A. Rodriguez, Maree J. Webster, Steven D. Sheridan, Constantine N. Logothetis, Carl M. Sellgren, Nikolaos Mellios, Lauren L. Jantzie
Publikováno v:
Neuropsychopharmacology
The ability of small secretory microvesicles known as exosomes to influence neuronal and glial function via their microRNA (miRNA) cargo has positioned them as a novel and effective method of cell-to-cell communication. However, little is known about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9121933eaecae9edf64ff7e64a0899
http://europepmc.org/articles/PMC7021900
http://europepmc.org/articles/PMC7021900
Publikováno v:
Alcohol Clin Exp Res
Background Fetal alcohol syndrome (FAS) due to gestational alcohol exposure represents one of the most common causes of non-heritable lifelong disability worldwide. In vitro and in vivo models have successfully recapitulated multiple facets of the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ba0cc50c2846b8a39dd3f83a5aff8f
https://pubmed.ncbi.nlm.nih.gov/33682149
https://pubmed.ncbi.nlm.nih.gov/33682149
Autor:
James B Aimone, Jason P. Weick
Publikováno v:
Frontiers in Computational Neuroscience, Vol 7 (2013)
Mathematical modeling of anatomically-constrained neural networks has provided significant insights regarding the response of networks to neurological disorders or injury. A logical extension of these models is to incorporate treatment regimens to in
Externí odkaz:
https://doaj.org/article/4fed597c3ebc474eb6607e773d0d68c3
X-ray mediated scintillation increases synaptic activity via Cerium-doped LSO and Channelrhodopsin-2
Autor:
Lori L. McMahon, Mary K. Burdette, Micah E. Bagley, Justin A. Barnes, Mark Bolding, Aundrea F. Bartley, Jason P. Weick, Lynn E. Dobrunz, Stephen H. Foulger, Máté Fischer, Kelli E. Cannon
Optogenetics is a widely used tool for studying neural circuits. However, non-invasive methods for light delivery in the brain are needed to avoid physical damage typically caused by intracranial insertion of light guides. An innovative strategy coul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1221fd9a4e6949a9cca7c21ea8b99ea9
https://doi.org/10.1101/2020.08.29.273359
https://doi.org/10.1101/2020.08.29.273359
