Zobrazeno 1 - 10
of 311
pro vyhledávání: '"Jason Morton"'
Autor:
Geraldine Przybylko, Darren Morton, Lillian Kent, Jason Morton, Jason Hinze, Peter Beamish, Mel Renfrew
Publikováno v:
BMC Psychology, Vol 9, Iss 1, Pp 1-11 (2021)
Abstract Background There is an urgent need for efficacious interventions to combat the global mental health crisis, and mental health promotion and primary prevention approaches are paramount. The aim of this study is to examine whether an online in
Externí odkaz:
https://doaj.org/article/d0839e7c452745e7907d476d020e1934
Publikováno v:
JMIR Mental Health, Vol 8, Iss 11, p e29866 (2021)
BackgroundThe global prevalence of mental health disorders is at a crisis point, particularly in the wake of COVID-19, prompting calls for the development of digital interdisciplinary mental health promotion interventions (MHPIs) for nonclinical coho
Externí odkaz:
https://doaj.org/article/00c1a96a2898437c910ee5efc0c1f30e
Autor:
Antonio Jimeno, Aik-Choon Tan, Marileila Varella-Garcia, Barbara A. Frederick, Francois Wilhelm, Dara L. Aisner, Sarah M. Takimoto, Daniel Sehrt, Brian W. Vogler, Gregory N. Gan, Justin Eagles-Soukup, Adrian Umpierrez, Phuong Le, J. Jason Morton, David P. Astling, Magdalena J. Glogowska, Daniel W. Bowles, Stephen B. Keysar, Ryan T. Anderson
PDF file - 64K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8e7717de4950956e210d0d4a5249dc
https://doi.org/10.1158/1535-7163.22497478
https://doi.org/10.1158/1535-7163.22497478
Autor:
Antonio Jimeno, Rene Gonzalez, Dennis R. Roop, William Robinson, Jing H. Wang, Xiao-Jing Wang, Theresa Medina, Hilary Somerset, Aik-Choon Tan, Dexiang Gao, Randi Yeager, Bettina Miller, Karina Gomez, Cera Nieto, Phuong N. Le, Loni Perrenoud, Julie Reisinger, Tugs-Saikhan Chimed, Stephen B. Keysar, Nathaniel Alzofon, J. Jason Morton
Resistance to immunotherapy is a significant challenge, and the scarcity of human models hinders the identification of the underlying mechanisms. To address this limitation, we constructed an autologous humanized mouse (aHM) model with hematopoietic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655a6f1c1b66b2ca94647218902d75a6
https://doi.org/10.1158/1541-7786.c.6545108.v1
https://doi.org/10.1158/1541-7786.c.6545108.v1
Autor:
Antonio Jimeno, Rene Gonzalez, Dennis R. Roop, William Robinson, Jing H. Wang, Xiao-Jing Wang, Theresa Medina, Hilary Somerset, Aik-Choon Tan, Dexiang Gao, Randi Yeager, Bettina Miller, Karina Gomez, Cera Nieto, Phuong N. Le, Loni Perrenoud, Julie Reisinger, Tugs-Saikhan Chimed, Stephen B. Keysar, Nathaniel Alzofon, J. Jason Morton
Table S1. Expanded HSPC engraftment into mouse cohorts Table S2. Human immune cell presence in HM tissues Table S3a. CUHM003 mutations present at diagnosis b. Additional CUHM003 mutations present at progression c. CUHM005 mutations present at diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c3fbcf5bdeea96081d6cb3e0e4b08c
https://doi.org/10.1158/1541-7786.22526474.v1
https://doi.org/10.1158/1541-7786.22526474.v1
Autor:
Antonio Jimeno, Aik-Choon Tan, Marileila Varella-Garcia, Barbara A. Frederick, Francois Wilhelm, Dara L. Aisner, Sarah M. Takimoto, Daniel Sehrt, Brian W. Vogler, Gregory N. Gan, Justin Eagles-Soukup, Adrian Umpierrez, Phuong Le, J. Jason Morton, David P. Astling, Magdalena J. Glogowska, Daniel W. Bowles, Stephen B. Keysar, Ryan T. Anderson
The dual pathway inhibitor rigosertib inhibits phosphoinositide 3-kinase (PI3K) pathway activation as well as polo-like kinase 1 (PLK1) activity across a broad spectrum of cancer cell lines. The importance of PIK3CA alterations in squamous cell carci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36906326f4b2438531275d5ad4819da3
https://doi.org/10.1158/1535-7163.c.6535627.v1
https://doi.org/10.1158/1535-7163.c.6535627.v1
Autor:
Antonio Jimeno, Xiao-Jing Wang, Hilary L. Somerset, Hongmei Zhou, Christian D. Young, Traci R. Lyons, Anit Tyagi, Farshad N. Chowdhury, Cera Nieto, Phuong N. Le, Tugs-Saikhan Chimed, Bettina Miller, J. Jason Morton, Stephen B. Keysar, FangLong Wu, Karina E. Gomez
Supplemental methods, figures, and table.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7733b2ccfea5fa2647bc8d16b3ec9517
https://doi.org/10.1158/0008-5472.22425550.v1
https://doi.org/10.1158/0008-5472.22425550.v1
Autor:
Antonio Jimeno, Tin Tin Su, David Raben, Xiao-Jing Wang, Aik-Choon Tan, Hilary L. Somerset, Gijsbertus J. Pronk, Barbara Frederick, Cera Nieto, Karina E. Gomez, Tugs-Saikhan Chimed, Julie Reisinger, J. Jason Morton, Phuong N. Le, Brian C. Jackson, Bettina Miller, Nathan Gomes, Stephen B. Keysar
SF1 is related to Fig. 1 and Fig. 2. SVC112 inhibits tumor cells growth and enhances the effects of radiation. SF2 is related to Fig. 3. SVC112 combined with radiation inhibits growth of HNSCC PDX tumors. SF3. Ribo-seq analysis of HNSCC cells treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2738786f1307fb8529f2039916a953
https://doi.org/10.1158/0008-5472.22424839
https://doi.org/10.1158/0008-5472.22424839
Autor:
Antonio Jimeno, Tin Tin Su, David Raben, Xiao-Jing Wang, Aik-Choon Tan, Hilary L. Somerset, Gijsbertus J. Pronk, Barbara Frederick, Cera Nieto, Karina E. Gomez, Tugs-Saikhan Chimed, Julie Reisinger, J. Jason Morton, Phuong N. Le, Brian C. Jackson, Bettina Miller, Nathan Gomes, Stephen B. Keysar
Cancer stem cells (CSC) drive growth, therapy resistance, and recurrence in head and neck squamous cell carcinoma (HNSCC). Regulation of protein translation is crucial for normal stem cells and CSCs; its inhibition could disrupt stemness properties,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e245f39ab17025ce2bac7616dc4b2b11
https://doi.org/10.1158/0008-5472.c.6511879
https://doi.org/10.1158/0008-5472.c.6511879
Autor:
Antonio Jimeno, Xiao-Jing Wang, John I. Song, Andrew Thorburn, M. Scott Lucia, Fred R. Hirsch, Hilary Serracino, Justin R. Eagles-Soukup, Gregory N. Gan, Daniel B. Sehrt, Sarah M. Takimoto, Magdalena J. Glogowska, Pamela Fernandez, Jackie Thorburn, Brian W. Vogler, Jeramiah J. Paylor, Daniel W. Bowles, J. Jason Morton, Ryan T. Anderson, Phuong N. Le, Stephen B. Keysar
PDF file - 1255K, Confirmation of GLI1 modulation by EGFR activation (S1); Epithelial gene expression profile and morphology predicts erlotinib sensitivity in HNSCC cell lines (S2); Zeb1 transcription factor is key driver of EGF induced EMT (S3); EGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974366581a1d358ebdce703ca2a05791
https://doi.org/10.1158/0008-5472.22397691.v1
https://doi.org/10.1158/0008-5472.22397691.v1