Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jason Malia"'
Autor:
Nicholas C. Turner, Juanita S. Lopez, Timothy A. Yap, Emma Hall, Alison Turner, Florence I. Raynaud, Ruth Ruddle, Karen E. Swales, Jason Malia, Laura Finneran, Toby Prout, Mona Parmar, Jenny King, Margaret Hills, Michael Hubank, Paula Z. Proszek, Heidrun Gevensleben, Sarah Hrebien, Alex Pearson, Isaac Garcia-Murillas, Maria Teresa Herrera-Abreu, Rosalind J. Cutts, Alicia F.C. Okines, Alistair Ring, Anne C. Armstrong, Iain R. Macpherson, Joline S.J. Lim, Javier Pascual
Escalation phase dose levels and final recruitment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbcf33f6c433c0a43b2c0b533ff6f99
https://doi.org/10.1158/2159-8290.22535459.v1
https://doi.org/10.1158/2159-8290.22535459.v1
Autor:
Nicholas C. Turner, Juanita S. Lopez, Timothy A. Yap, Emma Hall, Alison Turner, Florence I. Raynaud, Ruth Ruddle, Karen E. Swales, Jason Malia, Laura Finneran, Toby Prout, Mona Parmar, Jenny King, Margaret Hills, Michael Hubank, Paula Z. Proszek, Heidrun Gevensleben, Sarah Hrebien, Alex Pearson, Isaac Garcia-Murillas, Maria Teresa Herrera-Abreu, Rosalind J. Cutts, Alicia F.C. Okines, Alistair Ring, Anne C. Armstrong, Iain R. Macpherson, Joline S.J. Lim, Javier Pascual
Baseline tissue biomarker analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b64d725e62326fa4fbc9ae6bd1b3db
https://doi.org/10.1158/2159-8290.22535447
https://doi.org/10.1158/2159-8290.22535447
Autor:
Nicholas C. Turner, Juanita S. Lopez, Timothy A. Yap, Emma Hall, Alison Turner, Florence I. Raynaud, Ruth Ruddle, Karen E. Swales, Jason Malia, Laura Finneran, Toby Prout, Mona Parmar, Jenny King, Margaret Hills, Michael Hubank, Paula Z. Proszek, Heidrun Gevensleben, Sarah Hrebien, Alex Pearson, Isaac Garcia-Murillas, Maria Teresa Herrera-Abreu, Rosalind J. Cutts, Alicia F.C. Okines, Alistair Ring, Anne C. Armstrong, Iain R. Macpherson, Joline S.J. Lim, Javier Pascual
RMH200 panel design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463cc86a1d265fa62da6f6887c6a661c
https://doi.org/10.1158/2159-8290.22535438.v1
https://doi.org/10.1158/2159-8290.22535438.v1
Autor:
Nicholas C. Turner, Juanita S. Lopez, Timothy A. Yap, Emma Hall, Alison Turner, Florence I. Raynaud, Ruth Ruddle, Karen E. Swales, Jason Malia, Laura Finneran, Toby Prout, Mona Parmar, Jenny King, Margaret Hills, Michael Hubank, Paula Z. Proszek, Heidrun Gevensleben, Sarah Hrebien, Alex Pearson, Isaac Garcia-Murillas, Maria Teresa Herrera-Abreu, Rosalind J. Cutts, Alicia F.C. Okines, Alistair Ring, Anne C. Armstrong, Iain R. Macpherson, Joline S.J. Lim, Javier Pascual
Pharmacokinetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539cd7671c3c7ea23621ce2180203d50
https://doi.org/10.1158/2159-8290.22535453.v1
https://doi.org/10.1158/2159-8290.22535453.v1
Autor:
Nicholas C. Turner, Juanita S. Lopez, Timothy A. Yap, Emma Hall, Alison Turner, Florence I. Raynaud, Ruth Ruddle, Karen E. Swales, Jason Malia, Laura Finneran, Toby Prout, Mona Parmar, Jenny King, Margaret Hills, Michael Hubank, Paula Z. Proszek, Heidrun Gevensleben, Sarah Hrebien, Alex Pearson, Isaac Garcia-Murillas, Maria Teresa Herrera-Abreu, Rosalind J. Cutts, Alicia F.C. Okines, Alistair Ring, Anne C. Armstrong, Iain R. Macpherson, Joline S.J. Lim, Javier Pascual
Progression free survival by baseline ESR1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39903ee85d8d0887de04c64015292597
https://doi.org/10.1158/2159-8290.22535441
https://doi.org/10.1158/2159-8290.22535441
Autor:
Nicholas C. Turner, Juanita S. Lopez, Timothy A. Yap, Emma Hall, Alison Turner, Florence I. Raynaud, Ruth Ruddle, Karen E. Swales, Jason Malia, Laura Finneran, Toby Prout, Mona Parmar, Jenny King, Margaret Hills, Michael Hubank, Paula Z. Proszek, Heidrun Gevensleben, Sarah Hrebien, Alex Pearson, Isaac Garcia-Murillas, Maria Teresa Herrera-Abreu, Rosalind J. Cutts, Alicia F.C. Okines, Alistair Ring, Anne C. Armstrong, Iain R. Macpherson, Joline S.J. Lim, Javier Pascual
Circulating tumor DNA dynamics as a surrogate of efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b4d6b5043c1aba599074c22ab36045
https://doi.org/10.1158/2159-8290.22535444.v1
https://doi.org/10.1158/2159-8290.22535444.v1
Autor:
Nicholas C. Turner, Juanita S. Lopez, Timothy A. Yap, Emma Hall, Alison Turner, Florence I. Raynaud, Ruth Ruddle, Karen E. Swales, Jason Malia, Laura Finneran, Toby Prout, Mona Parmar, Jenny King, Margaret Hills, Michael Hubank, Paula Z. Proszek, Heidrun Gevensleben, Sarah Hrebien, Alex Pearson, Isaac Garcia-Murillas, Maria Teresa Herrera-Abreu, Rosalind J. Cutts, Alicia F.C. Okines, Alistair Ring, Anne C. Armstrong, Iain R. Macpherson, Joline S.J. Lim, Javier Pascual
Cyclin-dependent kinase 4/6 (CDK4/6) and PI3K inhibitors synergize in PIK3CA-mutant ER-positive HER2-negative breast cancer models. We conducted a phase Ib trial investigating the safety and efficacy of doublet CDK4/6 inhibitor palbociclib plus selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2188840c665bdd2ddabfa9e80f44d33
https://doi.org/10.1158/2159-8290.c.6547859.v1
https://doi.org/10.1158/2159-8290.c.6547859.v1
Autor:
Nicholas C. Turner, Juanita S. Lopez, Timothy A. Yap, Emma Hall, Alison Turner, Florence I. Raynaud, Ruth Ruddle, Karen E. Swales, Jason Malia, Laura Finneran, Toby Prout, Mona Parmar, Jenny King, Margaret Hills, Michael Hubank, Paula Z. Proszek, Heidrun Gevensleben, Sarah Hrebien, Alex Pearson, Isaac Garcia-Murillas, Maria Teresa Herrera-Abreu, Rosalind J. Cutts, Alicia F.C. Okines, Alistair Ring, Anne C. Armstrong, Iain R. Macpherson, Joline S.J. Lim, Javier Pascual
Efficacy of doublet palbociclib plus taselesib in advanced solid tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7d3790fee66fe4660e6888af32c34a
https://doi.org/10.1158/2159-8290.22535450
https://doi.org/10.1158/2159-8290.22535450
Autor:
Heidrun Gevensleben, Alistair Ring, Toby Prout, Nicholas C. Turner, Alison Turner, Iain R. Macpherson, Paula Proszek, Alex Pearson, Mike Hubank, Rosalind J. Cutts, Karen E Swales, Sarah Hrebien, Javier Pascual, Margaret Hills, Maria Teresa Herrera-Abreu, Jenny King, Jason Malia, Anne C Armstrong, Ruth Ruddle, Alicia Okines, Isaac Garcia-Murillas, Emma Hall, Mona Parmar, Laura Finneran, Florence I. Raynaud, Timothy A. Yap, Juanita Lopez, Joline S.J. Lim
Publikováno v:
Cancer Discovery. 11:92-107
Cyclin-dependent kinase 4/6 (CDK4/6) and PI3K inhibitors synergize in PIK3CA-mutant ER-positive HER2-negative breast cancer models. We conducted a phase Ib trial investigating the safety and efficacy of doublet CDK4/6 inhibitor palbociclib plus selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc13c93ea6f30c16d07e987d3d4eab87
https://doi.org/10.1158/2159-8290.cd-20-0553
https://doi.org/10.1158/2159-8290.cd-20-0553
Autor:
Javier, Pascual, Joline S J, Lim, Iain R, Macpherson, Anne C, Armstrong, Alistair, Ring, Alicia F C, Okines, Rosalind J, Cutts, Maria Teresa, Herrera-Abreu, Isaac, Garcia-Murillas, Alex, Pearson, Sarah, Hrebien, Heidrun, Gevensleben, Paula Z, Proszek, Michael, Hubank, Margaret, Hills, Jenny, King, Mona, Parmar, Toby, Prout, Laura, Finneran, Jason, Malia, Karen E, Swales, Ruth, Ruddle, Florence I, Raynaud, Alison, Turner, Emma, Hall, Timothy A, Yap, Juanita S, Lopez, Nicholas C, Turner
Publikováno v:
Cancer discovery. 11(1)
Cyclin-dependent kinase 4/6 (CDK4/6) and PI3K inhibitors synergize in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b9c64381d2866223d1d769ddb2c4968
https://pubmed.ncbi.nlm.nih.gov/32958578
https://pubmed.ncbi.nlm.nih.gov/32958578