Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jason Macrander"'
Autor:
Edward G. Smith, Joachim M. Surm, Jason Macrander, Adi Simhi, Guy Amir, Maria Y. Sachkova, Magda Lewandowska, Adam M. Reitzel, Yehu Moran
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Venom is a complex trait with unresolved underlying toxin expression dynamics. Here, the authors compare expression across sea anemone species, revealing variation in dominant toxin diploid copy number across populations which generates distinct hapl
Externí odkaz:
https://doaj.org/article/819f1ff4463743b88a496486a1b92143
Publikováno v:
Biology and Life Sciences Forum, Vol 24, Iss 1, p 11 (2023)
Russell’s viper (Daboia siamensis) is a medically important snake in Myanmar due to its high morbidity and mortality. The genome of Myanmar Russell’s viper had not been sequenced until recently. Hence, RNA sequencing has been used to predict gene
Externí odkaz:
https://doaj.org/article/d0816347543548aeb7ff315ebbc016dd
Publikováno v:
Toxins, Vol 15, Iss 5, p 309 (2023)
The Russell’s viper (Daboia siamensis) is a medically important venomous snake in Myanmar. Next-generation sequencing (NGS) shows potential to investigate the venom complexity, giving deeper insights into snakebite pathogenesis and possible drug di
Externí odkaz:
https://doaj.org/article/970a1a52557743e0823e9a8f89f08b43
Autor:
Maria Y. Sachkova, Jason Macrander, Joachim M. Surm, Reuven Aharoni, Shelcie S. Menard-Harvey, Amy Klock, Whitney B. Leach, Adam M. Reitzel, Yehu Moran
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-13 (2020)
Abstract Background In cnidarians, antagonistic interactions with predators and prey are mediated by their venom, whose synthesis may be metabolically expensive. The potentially high cost of venom production has been hypothesized to drive population-
Externí odkaz:
https://doaj.org/article/d4fab23eb10b4296b6cbdd019e3e2e63
Publikováno v:
Marine Drugs, Vol 20, Iss 12, p 730 (2022)
Sea anemones are predatory marine invertebrates and have diverse venom arsenals. Venom is integral to their biology, and is used in competition, defense, and feeding. Three lineages of sea anemones are known to have independently evolved symbiotic re
Externí odkaz:
https://doaj.org/article/de304ed060264f0a9483aa8050be5c28
Publikováno v:
Marine Drugs, Vol 18, Iss 8, p 413 (2020)
Tube anemones, or cerianthids, are a phylogenetically informative group of cnidarians with complex life histories, including a pelagic larval stage and tube-dwelling adult stage, both known to utilize venom in stinging-cell rich tentacles. Cnidarians
Externí odkaz:
https://doaj.org/article/eaffb465f1ae433f81197a7bce0ce858
Autor:
Anna V. Ivanina, Ballav Borah, Tadas Rimkevicius, Jason Macrander, Helen Piontkivska, Inna M. Sokolova, Elia Beniash
Publikováno v:
Frontiers in Marine Science, Vol 5 (2018)
Vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) play a role in early development, organogenesis, and regeneration, as well as biomineralization of invertebrates. The involvement of VEGF and VEGFR in b
Externí odkaz:
https://doaj.org/article/09e0b2b6b6dd46d1b272633b7700b478
Publikováno v:
PeerJ, Vol 6, p e5361 (2018)
The advent of next-generation sequencing has resulted in transcriptome-based approaches to investigate functionally significant biological components in a variety of non-model organism. This has resulted in the area of “venomics”: a rapidly growi
Externí odkaz:
https://doaj.org/article/fd5c04f0aa774f9d811767654bda0fcb
Autor:
Yaara Y Columbus-Shenkar, Maria Y Sachkova, Jason Macrander, Arie Fridrich, Vengamanaidu Modepalli, Adam M Reitzel, Kartik Sunagar, Yehu Moran
Publikováno v:
eLife, Vol 7 (2018)
Little is known about venom in young developmental stages of animals. The appearance of toxins and stinging cells during early embryonic stages in the sea anemone Nematostella vectensis suggests that venom is already expressed in eggs and larvae of t
Externí odkaz:
https://doaj.org/article/a06ab5eb4cc84be7ae63f8eb520d282a
Autor:
Jason Macrander, Marymegan Daly
Publikováno v:
Toxins, Vol 8, Iss 12, p 368 (2016)
Sea anemones (Cnidaria, Anthozoa, and Actiniaria) use toxic peptides to incapacitate and immobilize prey and to deter potential predators. Their toxin arsenal is complex, targeting a variety of functionally important protein complexes and macromolecu
Externí odkaz:
https://doaj.org/article/3432173922b64d238e46d153ff21d5c8