Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jason M. Osinski"'
Autor:
David Gokhman, Malka Nissim-Rafinia, Lily Agranat-Tamir, Genevieve Housman, Raquel García-Pérez, Esther Lizano, Olivia Cheronet, Swapan Mallick, Maria A. Nieves-Colón, Heng Li, Songül Alpaslan-Roodenberg, Mario Novak, Hongcang Gu, Jason M. Osinski, Manuel Ferrando-Bernal, Pere Gelabert, Iddi Lipende, Deus Mjungu, Ivanela Kondova, Ronald Bontrop, Ottmar Kullmer, Gerhard Weber, Tal Shahar, Mona Dvir-Ginzberg, Marina Faerman, Ellen E. Quillen, Alexander Meissner, Yonatan Lahav, Leonid Kandel, Meir Liebergall, María E. Prada, Julio M. Vidal, Richard M. Gronostajski, Anne C. Stone, Benjamin Yakir, Carles Lalueza-Fox, Ron Pinhasi, David Reich, Tomas Marques-Bonet, Eran Meshorer, Liran Carmel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
How traits specific to modern humans have evolved is difficult to study. Here, Gokhman et al. compare measured and reconstructed DNA methylation maps of present-day humans, archaic humans and chimpanzees and find that genes that affect vocal tract an
Externí odkaz:
https://doaj.org/article/f72a64784f804644b521ad8a4ae77ab7
Autor:
Elizaveta V. Bashkirova, Nell Klimpert, Ariel Pourmorady, Kevin Monahan, Christine E. Campbell, Jason M. Osinski, Longzhi Tan, Ira Schieren, Beka Stecky, Gilad Barnea, X. Sunney Xie, Ishmail Abdus-Saboor, Benjamin Shykind, Bianca Jones Marlin, Richard M. Gronostajski, Alexander Fleischmann, Stavros Lomvardas
Publikováno v:
bioRxiv
Olfactory receptor (OR) choice represents an example of genetically hardwired stochasticity, where every olfactory neuron expresses one out of ~2000 OR alleles in a probabilistic, yet stereotypic fashion. Here, we show that topographic restrictions i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442d805e4a48d07128c580ad2a789888
https://europepmc.org/articles/PMC10055043/
https://europepmc.org/articles/PMC10055043/
Autor:
Caitríona O'Connor, Joana Campos, Jason M Osinski, Richard M Gronostajski, Alison M Michie, Karen Keeshan
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120102 (2015)
The commitment of stem and progenitor cells toward specific hematopoietic lineages is tightly controlled by a number of transcription factors that regulate differentiation programs via the expression of lineage restricting genes. Nuclear factor one (
Externí odkaz:
https://doaj.org/article/7b3c6395e167472f9b6ae493eb3d4077
Autor:
Kevin Monahan, Gilad Barnea, Stavros Lomvardas, Richard M. Gronostajski, Elizaveta Bashkirova, Longzhi Tan, Jason M. Osinski, Christine E. Campbell, X. Sunnie Xie, Ira Schieren
Expression of one out of >1000 olfactory receptor (OR) genes is stochastic but, yet, spatially organized in stereotypic anatomical segments, or “zones”, along the dorsoventral axis of the mouse olfactory epithelium. We discovered that zonal OR ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a43dcba94e7f7330c64f7db970cad9d7
https://doi.org/10.1101/2020.08.30.274035
https://doi.org/10.1101/2020.08.30.274035
Autor:
Mona Dvir-Ginzberg, Malka Nissim-Rafinia, Tal Shahar, Iddi Lipende, Ronald E. Bontrop, David Reich, Lily Agranat-Tamir, Liran Carmel, Heng Li, Ottmar Kullmer, Yonatan Lahav, Genevieve Housman, Eran Meshorer, Maria A. Nieves-Colón, Olivia Cheronet, Marina Faerman, Richard M. Gronostajski, David Gokhman, Leonid Kandel, Mario Novak, Julio M. Vidal, Carles Lalueza-Fox, Raquel García-Pérez, Anne C. Stone, Esther Lizano, Songül Alpaslan-Roodenberg, Benjamin Yakir, Ellen E. Quillen, Hongcang Gu, Alexander Meissner, Deus Mjungu, Ron Pinhasi, Gerhard W. Weber, Swapan Mallick, Jason M. Osinski, María E. Prada, Manuel Ferrando-Bernal, Tomas Marques-Bonet, Pere Gelabert, Meir Liebergall, Ivanela Kondova
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Nature Communications, 11(1). Nature Publishing Group
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Universitat Autònoma de Barcelona
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Nature Communications, 11(1). Nature Publishing Group
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Changes in potential regulatory elements are thought to be key drivers of phenotypic divergence. However, identifying changes to regulatory elements that underlie human-specific traits has proven very challenging. Here, we use 63 reconstructed and ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0157e05b1b124af13af9f888d04587
https://ddd.uab.cat/record/234397
https://ddd.uab.cat/record/234397
Autor:
Lachlan Harris, Yee Hsieh Evelyn Heng, Jason M. Osinski, Diana Vidovic, Paul Q. Thomas, Timothy L. Bailey, Michael Piper, James N. Hughes, Aaron G. Smith, Richard M. Gronostajski, Tracey J. Harvey
Publikováno v:
Brain Research. 1616:71-87
Nuclear factor one X (NFIX) has been shown to play a pivotal role during the development of many regions of the brain, including the neocortex, the hippocampus and the cerebellum. Mechanistically, NFIX has been shown to promote neural stem cell diffe
Autor:
Christine E. Campbell, Richard M. Gronostajski, Celine Plachez, Randal X. Moldrich, Jason M. Osinski, Charlotta Lindwall, Michael Piper, Nana Sunn, Linda J. Richards
Publikováno v:
The Journal of Comparative Neurology. 508:385-401
Three members of the Nuclear Factor I (Nfi) gene family of transcription factors; Nfia, Nfib, and Nfix are highly expressed in the developing mouse brain. Nfia and Nfib knockout mice display profound defects in the development of midline glial popula
Autor:
Jason M. Osinski, Michael Piper, Christine E. Campbell, Ben Martynoga, Juan L. Mateo, Fraser J. Sim, Richard M. Gronostajski, François Guillemot, Bo Zhou
Publikováno v:
Stem cells and development. 24(18)
Murine postnatal neural stem cells (NSCs) give rise to neurons, astrocytes, or oligodendrocytes (OLs); however, our knowledge of the genes that control this lineage specification is incomplete. In this study, we show that nuclear factor I X (NFIX), a
Autor:
Diana Vidovic, Lachlan Harris, Oressia Zalucki, Jens Bunt, Linda J. Richards, Richard M. Gronostajski, Timothy R. O'Connor, Yunan Ye, Michael Piper, Johnathon W. C. Lim, Jason M. Osinski
Publikováno v:
Brain and Neuroscience Advances
Background: Nuclear factor I family members nuclear factor I A and nuclear factor I B play important roles during cerebral cortical development. Nuclear factor I A and nuclear factor I B regulate similar biological processes, as their expression patt
Autor:
Joan S. Baizer, Christine E. Campbell, Yu-Ting Yeh, Michael Piper, E. David Litwack, Richard M. Gronostajski, Celine Plachez, Jason M. Osinski, Linda J. Richards
Publikováno v:
BMC Developmental Biology
BMC Developmental Biology, Vol 8, Iss 1, p 52 (2008)
BMC Developmental Biology, Vol 8, Iss 1, p 52 (2008)
Background The Nuclear Factor I (NFI) multi-gene family encodes site-specific transcription factors essential for the development of a number of organ systems. We showed previously that Nfia-deficient mice exhibit agenesis of the corpus callosum and