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pro vyhledávání: '"Jason M. Ochoada"'
Autor:
Betty H. Yagi, Ronda D. Schaadt, Gary E. Zurenko, Judith C. Hamel, Judy K. Moerman, Jason M. Ochoada, Lisa Marie Thomasco, Douglas Stapert, Elizabeth A. Weaver, Ford Charles W, Robert C. Gadwood
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(23)
Replacement of the morpholine C-ring of linezolid 1 with a 1,3,4-thiadiazolyl ring leads to oxazolidinone analogues 5 having potent antibacterial activity against both gram-positive and gram-negative organisms. Conversion of the C5 acetamide group to