Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jason M. Carte"'
Autor:
Colin McGaw, Anthony J. Garrity, Gabrielle Z. Munoz, Jeffrey R. Haswell, Sejuti Sengupta, Elise Keston-Smith, Pratyusha Hunnewell, Alexa Ornstein, Mishti Bose, Quinton Wessells, Noah Jakimo, Paul Yan, Huaibin Zhang, Lauren E. Alfonse, Roy Ziblat, Jason M. Carte, Wei-Cheng Lu, Derek Cerchione, Brendan Hilbert, Shanmugapriya Sothiselvam, Winston X. Yan, David R. Cheng, David A. Scott, Tia DiTommaso, Shaorong Chong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Cas12i is a genome editing platform with compact size that fits in AAV vector with short 43-mer gRNA, absence of tracrRNA, ability to process pre-crRNA, and high specificity. Here the authors present an unbiased mutational scanning approach to engine
Externí odkaz:
https://doaj.org/article/b34236ad23cc4e1cb4a7c8a576cc399b
Autor:
Carsten T. Charlesworth, Joab Camarena, M. Kyle Cromer, Sriram Vaidyanathan, Rasmus O. Bak, Jason M. Carte, Jason Potter, Daniel P. Dever, Matthew H. Porteus
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 12, Iss , Pp 89-104 (2018)
Engineered nuclease-mediated gene targeting through homologous recombination (HR) in hematopoietic stem and progenitor cells (HSPCs) has the potential to treat a variety of genetic hematologic and immunologic disorders. Here, we identify critical par
Externí odkaz:
https://doaj.org/article/c3df848dbdcf49debfbcacf34af2f508
Autor:
Lauren E. Alfonse, David R. Cheng, Elise Keston-Smith, Anthony J. Garrity, Jason M. Carte, Eugene V. Koonin, Pratyusha Hunnewell, Shaorong Chong, David Scott, Shanmugapriya Sothiselvam, Kira S. Makarova, Winston X. Yan
Publikováno v:
Science (New York, N.Y.). 363(6422)
Additional, diverse CRISPR systems CRISPR systems have been revolutionizing molecular biology. Mining the metagenomic database, Yan et al. systematically discovered additional subtypes of type V CRISPR-Cas systems. The additional Cas12 effectors disp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75481061a93c976c932d3ab9a064e070
https://pubmed.ncbi.nlm.nih.gov/31021231
https://pubmed.ncbi.nlm.nih.gov/31021231