Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jason M Szafron"'
Autor:
Sumeda Nandadasa, Jason M Szafron, Vai Pathak, Sae-Il Murtada, Caroline M Kraft, Anna O'Donnell, Christian Norvik, Clare Hughes, Bruce Caterson, Miriam S Domowicz, Nancy B Schwartz, Karin Tran-Lundmark, Martina Veigl, David Sedwick, Elliot H Philipson, Jay D Humphrey, Suneel S Apte
Publikováno v:
eLife, Vol 9 (2020)
The umbilical artery lumen closes rapidly at birth, preventing neonatal blood loss, whereas the umbilical vein remains patent longer. Here, analysis of umbilical cords from humans and other mammals identified differential arterial-venous proteoglycan
Externí odkaz:
https://doaj.org/article/9109ace5da5c44e6ba1fbd9d2ece7d9d
Autor:
Kevin M. Blum, Jacob C. Zbinden, Abhay B. Ramachandra, Stephanie E. Lindsey, Jason M. Szafron, James W. Reinhardt, Megan Heitkemper, Cameron A. Best, Gabriel J. M. Mirhaidari, Yu-Chun Chang, Anudari Ulziibayar, John Kelly, Kejal V. Shah, Joseph D. Drews, Jason Zakko, Shinka Miyamoto, Yuichi Matsuzaki, Ryuma Iwaki, Hira Ahmad, Robbie Daulton, Drew Musgrave, Matthew G. Wiet, Eric Heuer, Emily Lawson, Erica Schwarz, Michael R. McDermott, Rajesh Krishnamurthy, Ramkumar Krishnamurthy, Kan Hor, Aimee K. Armstrong, Brian A. Boe, Darren P. Berman, Aaron J. Trask, Jay D. Humphrey, Alison L. Marsden, Toshiharu Shinoka, Christopher K. Breuer
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-21 (2022)
Plain language summary Surgery to correct defects in the heart that are present at birth sometimes requires the use of artificial blood vessels called vascular grafts. Tissue-engineered vascular grafts (TEVGs) are scaffolds seeded with cells that can
Externí odkaz:
https://doaj.org/article/cf83b6fbad07439fa512a6b4905d7efd
Autor:
Erica L. Schwarz, John M. Kelly, Kevin M. Blum, Kan N. Hor, Andrew R. Yates, Jacob C. Zbinden, Aekaansh Verma, Stephanie E. Lindsey, Abhay B. Ramachandra, Jason M. Szafron, Jay D. Humphrey, Toshiharu Shin’oka, Alison L. Marsden, Christopher K. Breuer
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-17 (2021)
Abstract In the field of congenital heart surgery, tissue-engineered vascular grafts (TEVGs) are a promising alternative to traditionally used synthetic grafts. Our group has pioneered the use of TEVGs as a conduit between the inferior vena cava and
Externí odkaz:
https://doaj.org/article/f6b80589f56f438bab2b69bc93a66f5a
Autor:
Erica L. Schwarz, John M. Kelly, Kevin M. Blum, Kan N. Hor, Andrew R. Yates, Jacob C. Zbinden, Aekaansh Verma, Stephanie E. Lindsey, Abhay B. Ramachandra, Jason M. Szafron, Jay D. Humphrey, Toshiharu Shin’oka, Alison L. Marsden, Christopher K. Breuer
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/50963db2ca1b484584a40b56c1bbdf6e
Autor:
Jason M. Szafron, Weiguang Yang, Jeffrey A. Feinstein, Marlene Rabinovitch, Alison L. Marsden
Publikováno v:
bioRxiv
Hemodynamic loading is known to contribute to the development and progression of pulmonary arterial hypertension (PAH). This loading drives changes in mechanobiological stimuli that affect cellular phenotypes and lead to pulmonary vascular remodeling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56e9fa30d43fc82848d7932dbbf1d0f
https://europepmc.org/articles/PMC10153237/
https://europepmc.org/articles/PMC10153237/
Autor:
Aekaansh Verma, Erica L. Schwarz, Alison L. Marsden, Jay D. Humphrey, Jacob C. Zbinden, Stephanie E. Lindsey, Kevin M. Blum, John Kelly, Jason M. Szafron, Abhay B. Ramachandra, Toshiharu Shinoka, Andrew R. Yates, Christopher K. Breuer, Kan N. Hor
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-17 (2021)
NPJ Regenerative Medicine
NPJ Regenerative Medicine
In the field of congenital heart surgery, tissue-engineered vascular grafts (TEVGs) are a promising alternative to traditionally used synthetic grafts. Our group has pioneered the use of TEVGs as a conduit between the inferior vena cava and the pulmo
Publikováno v:
Biomech Model Mechanobiol
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
[EN] Methods of tissue engineering continue to advance, and multiple clinical trials are underway evaluating tissue engineered vascular grafts (TEVGs). Whereas initial concerns focused on suture retention and burst pressure, there is now a pressing n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6dafd8cdf5e5b2e2743557b59a07097
https://doi.org/10.1007/s10237-022-01562-9
https://doi.org/10.1007/s10237-022-01562-9
Autor:
Jay D. Humphrey, Ramak Khosravi, Christopher K. Breuer, Daniele E. Schiavazzi, Jason M. Szafron, Abhay B. Ramachandra
Publikováno v:
Integr Biol (Camb)
Stenosis is the primary complication of current tissue-engineered vascular grafts used in pediatric congenital cardiac surgery. Murine models provide considerable insight into the possible mechanisms underlying this situation, but they are not effici
Publikováno v:
Annals of Biomedical Engineering
Annals of Biomedical Engineering, 49(9), 2454-2467. Springer, Cham
Annals of Biomedical Engineering, 49(9), 2454-2467. Springer, Cham
Mechanical testing and constitutive modelling of isolated arterial layers yields insight into the individual layers’ mechanical properties, but per se fails to recapitulate the in vivo loading state, neglecting layer-specific residual stresses. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abfd2646e11b9dc0f8b4d745957f756
https://bura.brunel.ac.uk/handle/2438/22970
https://bura.brunel.ac.uk/handle/2438/22970
Autor:
Ramak Khosravi, Jacob C. Zbinden, Brooks V. Udelsman, Jay D. Humphrey, Tai Yi, Hirotsugu Kurobe, Toshiharu Shinoka, Jason M. Szafron, Shuhei Tara, Kevin A. Rocco, Mark Maxfield, Ethan W. Dean, Christopher K. Breuer, Cameron A. Best, Paul S. Bagi
Publikováno v:
Acta Biomater
Electrospinning is commonly used to generate polymeric scaffolds for tissue engineering. Using this approach, we developed a small-diameter tissue engineered vascular graft (TEVG) composed of poly-e-caprolactone-co- l -lactic acid (PCLA) fibers and l