Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jason M Norman"'
Autor:
Richard R Stein, Takeshi Tanoue, Rose L Szabady, Shakti K Bhattarai, Bernat Olle, Jason M Norman, Wataru Suda, Kenshiro Oshima, Masahira Hattori, Georg K Gerber, Chris Sander, Kenya Honda, Vanni Bucci
Publikováno v:
eLife, Vol 7 (2018)
Manipulation of the gut microbiota holds great promise for the treatment of diseases. However, a major challenge is the identification of therapeutically potent microbial consortia that colonize the host effectively while maximizing immunologic outco
Externí odkaz:
https://doaj.org/article/f7c2a82e817f466bb137c0d58c064ec5
Autor:
Melissa Dsouza, Rajita Menon, Emily Crossette, Shakti K. Bhattarai, Jessica Schneider, Yun-Gi Kim, Shilpa Reddy, Silvia Caballero, Cintia Felix, Louis Cornacchione, Jared Hendrickson, Andrea R. Watson, Samuel S. Minot, Nick Greenfield, Lisa Schopf, Rose Szabady, Juan Patarroyo, William Smith, Pratibha Harrison, Ed J. Kuijper, Ciaran P. Kelly, Bernat Olle, Dmitri Bobilev, Jeffrey L. Silber, Vanni Bucci, Bruce Roberts, Jeremiah Faith, Jason M. Norman
Publikováno v:
Cell Host & Microbe, 30(4), 583-598.e8. CELL PRESS
Manipulation of the gut microbiota via fecal microbiota transplantation (FMT) has shown clinical promise in diseases such as recurrent Clostridioides difficile infection (rCDI). However, the variable nature of this approach makes it challenging to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d09823d48b803c9f7a60dbf0b671fc
https://hdl.handle.net/1887/3505720
https://hdl.handle.net/1887/3505720
Autor:
Thomas Louie, Yoav Golan, Sahil Khanna, Dmitri Bobilev, Nathalie Erpelding, Candida Fratazzi, Meg Carini, Rajita Menon, Mary Ruisi, Jason M. Norman, Jeremiah J. Faith, Bernat Olle, Minran Li, Jeffrey L. Silber, Darrell S. Pardi
Publikováno v:
JAMA. 329:1356
ImportanceThe effect of rationally defined nonpathogenic, nontoxigenic, commensal strains of Clostridia on prevention of Clostridioides difficile infection (CDI) is unknown.ObjectiveTo determine the efficacy of VE303, a defined bacterial consortium o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c92c5ee724eaaa6798db8f4c438ac7f
https://doi.org/10.1001/jama.2023.4314
https://doi.org/10.1001/jama.2023.4314
Autor:
Youxian Li, Eiichiro Watanabe, Yusuke Kawashima, Damian R. Plichta, Zhujun Wang, Makoto Ujike, Qi Yan Ang, Runrun Wu, Munehiro Furuichi, Kozue Takeshita, Koji Yoshida, Keita Nishiyama, Sean M. Kearney, Wataru Suda, Masahira Hattori, Satoshi Sasajima, Takahiro Matsunaga, Xiaoxi Zhang, Kazuto Watanabe, Jun Fujishiro, Jason M. Norman, Bernat Olle, Shutoku Matsuyama, Ho Namkoong, Yoshifumi Uwamino, Makoto Ishii, Koichi Fukunaga, Naoki Hasegawa, Osamu Ohara, Ramnik J. Xavier, Koji Atarashi, Kenya Honda
Increased levels of proteases, such as trypsin, in the distal intestine have been implicated in intestinal pathological conditions1–3. However, the players and mechanisms that underlie protease regulation in the intestinal lumen have remained uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c55bcf50b1c8790eb1861533dcb66d0
http://hdl.handle.net/10852/99193
http://hdl.handle.net/10852/99193
Autor:
Satoru Morita, Takeshi Tanoue, Kozue Takeshita, Yutaka Kawakami, Ashwin N. Skelly, Hera Vlamakis, Jason M. Norman, Kenya Honda, Makoto Suematsu, Bernat Olle, Vanni Bucci, Tomonori Yaguchi, Takashi Inoue, Koji Atarashi, Masahira Hattori, Iori Motoo, Keiko Yasuma-Mitobe, Daniel Mucida, Seiko Narushima, Bruce L. Roberts, Dieter Riethmacher, Ramnik J. Xavier, Atsushi Shiota, Damian R. Plichta, Yuki Sugiura, Wataru Suda, Kayoko Sugita, Tsuneyasu Kaisho
Publikováno v:
Nature. 565:600-605
There is a growing appreciation for the importance of the gut microbiota as a therapeutic target in various diseases. However, there are only a handful of known commensal strains that can potentially be used to manipulate host physiological functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24172d126eb8411e44ff097369b5c2a6
https://doi.org/10.1038/s41586-019-0878-z
https://doi.org/10.1038/s41586-019-0878-z
Autor:
Jason M. Norman, Bruce L. Roberts, Judy Wang, Diwakar Davar, Michael Cecchini, Zev A. Wainberg, Bernat Olle, Anita Ahmed Turk, Dmitri Bobilev, Rose L. Szabady, Martin Gutierrez
Publikováno v:
Cancer Research. 80:CT246-CT246
Background: Gut microbiome composition affects response to PD-1 blockade; and recent proof of concept studies suggest that gut microbiome manipulation is effective in reversing resistance to PD-1 blockade. VE800 is an oral live biotherapeutic consist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dd8c421835f203e8db75a18fab25ffe
https://doi.org/10.1158/1538-7445.am2020-ct246
https://doi.org/10.1158/1538-7445.am2020-ct246
Autor:
Melissa Dsouza, Jessica S. Schneider, Bruce L. Roberts, Dmitri Bobilev, Brian Klein, Vanni Bucci, Jason M. Norman, Bernat Olle, Shilpa P. Reddy
Publikováno v:
Gastroenterology. 158:S-15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc452a451c8ad25a5372bb19f5fa4ecb
https://doi.org/10.1016/s0016-5085(20)30718-6
https://doi.org/10.1016/s0016-5085(20)30718-6
Autor:
Timothy J. Nice, Herbert W. Virgin, Broc T. McCune, Helen M. Lazear, Megan T. Baldridge, Michael S. Diamond, Jason M. Norman, Maxim N. Artyomov
Publikováno v:
Science. 347:269-273
Turning viral persistence on and off Norovirus causes >90% of the world's gastroenteritis. Norovirus can establish persistent infections, which may contribute to its spread. How does norovirus establish itself as a permanentw resident of the gut and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b044e104ac5951ca765e4edd0ae5c9cf
https://doi.org/10.1126/science.1258100
https://doi.org/10.1126/science.1258100
Autor:
Wataru Suda, Rose L. Szabady, Masahira Hattori, Richard R. Stein, Takeshi Tanoue, Kenshiro Oshima, Chris Sander, Shakti K. Bhattarai, Georg K. Gerber, Jason M. Norman, Kenya Honda, Bernat Olle, Vanni Bucci
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Manipulation of the gut microbiota holds great promise for the treatment of diseases. However, a major challenge is the identification of therapeutically potent microbial consortia that colonize the host effectively while maximizing immunologic outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea104ade13f6d2e46d302a5e88eb36f0
https://pubmed.ncbi.nlm.nih.gov/29664397
https://pubmed.ncbi.nlm.nih.gov/29664397
Autor:
Christine Becker, Petric Kuballa, Johnathan Mercer, Herbert W. Virgin, Kara G. Lassen, Heiko Horn, Stuart L. Schreiber, Ömer H. Yilmaz, Steven A. Carr, Ta-Chiang Liu, Kara L. Conway, Alykhan F. Shamji, Jason M. Norman, Atul K. Bhan, Eduardo J. Villablanca, Jacob D. Jaffe, Morgan L. Becker, Robert J. Heath, Lola Fagbami, Khushbu Patel, Thaddeus S. Stappenbeck, Ramnik J. Xavier, Mark J. Daly, Joanna M. Peloquin
Publikováno v:
Proceedings of the National Academy of Sciences. 111:7741-7746
A coding polymorphism (Thr300Ala) in the essential autophagy gene, autophagy related 16-like 1 (ATG16L1), confers increased risk for the development of Crohn disease, although the mechanisms by which single disease-associated polymorphisms contribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e699aba15d5ef8ce4e1a5b0f96d4d67
https://doi.org/10.1073/pnas.1407001111
https://doi.org/10.1073/pnas.1407001111