Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jason M Conley"'
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187481 (2017)
Extracellular adenosine triphosphate (ATP) is a key purinergic signal that mediates cell-to-cell communication both within and between organ systems. We address the need for a robust and minimally invasive approach to measuring extracellular ATP by r
Externí odkaz:
https://doaj.org/article/9ae7d4a4725b46b888c44fe3c7c65acb
Publikováno v:
Sensors, Vol 19, Iss 15, p 3253 (2019)
Purinergic signals, such as extracellular adenosine triphosphate (ATP) and adenosine diphosphate (ADP), mediate intercellular communication and stress responses throughout mammalian tissues, but the dynamics of their release and clearance are still n
Externí odkaz:
https://doaj.org/article/45688ee61e774f7bb54b89dce8541003
Publikováno v:
Diabetes. 69
Aims: G protein-coupled receptors (GPCRs) in the intestinal enteroendocrine cells (EECs) regulate gut hormone secretion by responding to nutritional, microbial, and inflammatory factors, which contributes to the maintenance of glucose and energy home
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6683979e11a7890eaac2e0dab1aaa3d0
https://doi.org/10.2337/db20-1895-p
https://doi.org/10.2337/db20-1895-p
Autor:
Daniel J. Horan, Hyun Cheol Roh, Aaron C. Ericsson, Surabhi D. Abhyankar, Natalie D. Stull, Xiaocheng C. Dong, Alexander G. Robling, Hongxia Ren, Robert N. Bone, Austin M. Reilly, Shijun Yan, Jason M. Conley, Carmella Evans-Molina, Menghao Huang
Publikováno v:
The Journal of Biological Chemistry
Insulin resistance impairs postprandial glucose uptake through glucose transporter type 4 (GLUT4) and is the primary defect preceding type 2 diabetes. We previously generated an insulin-resistant mouse model with human GLUT4 promoter-driven insulin r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a1f584191ae8f0764e128eed5d78d0
https://doi.org/10.1016/j.jbc.2021.101431
https://doi.org/10.1016/j.jbc.2021.101431
Autor:
Shijun Yan, Jason M. Conley, Austin M. Reilly, Natalie D. Stull, Surabhi D. Abhyankar, Aaron C. Ericsson, Tatsuyoshi Kono, Andrei I. Molosh, Chandrashekhar A. Kubal, Carmella Evans-Molina, Hongxia Ren
Publikováno v:
Cell Reports. 38:110179
G protein-coupled receptors (GPCRs) in intestinal enteroendocrine cells (EECs) respond to nutritional, neural, and microbial cues and modulate the release of gut hormones. Here we show that Gpr17, an orphan GPCR, is co-expressed in glucagon-like pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e58c2920427147e3b9c8f1900003281
https://doi.org/10.1016/j.celrep.2021.110179
https://doi.org/10.1016/j.celrep.2021.110179
Autor:
Kristin L. Ayers, Hongxia Ren, Matthew D. Hall, Min Shen, Hu Zhu, Jason M. Conley, Rong Chen, Hongmao Sun
Publikováno v:
The Journal of Biological Chemistry
GPR17 is a G-protein-coupled receptor (GPCR) implicated in the regulation of glucose metabolism and energy homeostasis. Such evidence is primarily drawn from mouse knockout studies and suggests GPR17 as a potential novel therapeutic target for the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b92d42d693b9ea9ec26925da8f44bb3
https://doi.org/10.1016/j.jbc.2021.100881
https://doi.org/10.1016/j.jbc.2021.100881
Autor:
Hongxia Ren, Shijun Yan, Jason M. Conley, Sharon L. Wardlaw, Shudi Zhou, Sunil K Panigrahi, Patrick L. Sheets, Austin M. Reilly
Publikováno v:
Nutrition & Diabetes
Nutrition & Diabetes, Vol 9, Iss 1, Pp 1-12 (2019)
Nutrition & Diabetes, Vol 9, Iss 1, Pp 1-12 (2019)
Background Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARH) control energy homeostasis by sensing hormonal and nutrient cues and activating secondary melanocortin sensing neurons. We identified the expression of a G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38730a0a5f62c852b63171d0fd9a7e4
https://doi.org/10.1038/s41387-019-0096-7
https://doi.org/10.1038/s41387-019-0096-7
Autor:
Hongxia Ren, Jason M. Conley
Publikováno v:
Journal of the Endocrine Society
GPR17 is a G protein-coupled receptor (GPCR) implicated in the regulation of glucose metabolism and energy homeostasis. Our genetic knockout studies in rodents suggest that GPR17 is a potential therapeutic target for the treatment of metabolic diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07cd0226c2480f1a4589a983486c3819
http://europepmc.org/articles/PMC8090550
http://europepmc.org/articles/PMC8090550
Publikováno v:
The Biological Bulletin. 231:73-84
Adenosine triphosphate (ATP) is a universal mediator of metabolism and signaling across unicellular and multicellular species. There is a fundamental interdependence between the dynamics of ATP and the physiology that occurs inside and outside the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae34a4be484ce9263fec9701605edb51
https://doi.org/10.1086/689592
https://doi.org/10.1086/689592
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e977a30c4351639c3dffe0a152a5303
https://doi.org/10.1096/fasebj.2018.32.1_supplement.686.7
https://doi.org/10.1096/fasebj.2018.32.1_supplement.686.7