Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Jason M Ali"'
Autor:
Ibrahim Talal Fazmin, Jason M. Ali
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 9, p 373 (2023)
Prosthesis–patient mismatch (PPM) is defined as implanting a prosthetic that is insufficiently sized for the patient receiving it. PPM leads to high residual transvalvular gradients post-aortic valve replacement and consequently results in left ven
Externí odkaz:
https://doaj.org/article/8837e8ca44144616a5cdc1529c524058
Autor:
Taufiek K. Rajab, Jason M. Ali, Jules Hernández-Sánchez, Jennifer Mackie, Vincenzo Grimaudo, Silvia Sinichino, Christine Mills, Bushra Rana, John Dunning, Yasir Abu-Omar
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 15, Iss 1, Pp 1-6 (2020)
Abstract Background Approximately 250,000 heart valve operations are performed annually worldwide. An intensive research and development effort has led to progressively more advanced heart valve prostheses. The Carpentier-Edwards Perimount Magna Ease
Externí odkaz:
https://doaj.org/article/777ee10f0237454b81ba24d3b25f07e1
Autor:
M. Saeed Qureshi, Jawaher Alsughayyir, Manu Chhabra, Jason M. Ali, Martin J. Goddard, Chris Devine, Thomas M. Conlon, Michelle A. Linterman, Reza Motallebzadeh, Gavin J. Pettigrew
Publikováno v:
Data in Brief, Vol 22, Iss , Pp 647-657 (2019)
This data is related to the research article entitled “Germinal center humoral autoimmunity independently mediates progression of allograft vasculopathy” (Harper et al., 2016) [2]. The data presented here focuses on the humoral autoimmune respons
Externí odkaz:
https://doaj.org/article/df626946d39f4cb19d93b1dff87001a2
Autor:
Manu Chhabra, Jawaher Alsughayyir, M. Saeed Qureshi, Mekhola Mallik, Jason M. Ali, Ivonne Gamper, Ellen L. Moseley, Sarah Peacock, Vasilis Kosmoliaptsis, Martin J. Goddard, Michelle A. Linterman, Reza Motallebzadeh, Gavin J. Pettigrew
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Different profiles of alloantibody responses are observed in the clinic, with those that persist, often despite targeted treatment, associated with poorer long-term transplant outcomes. Although such responses would suggest an underlying germinal cen
Externí odkaz:
https://doaj.org/article/0bc102d620cb4014b3986867ba41750e
Autor:
Jawaher Alsughayyir, Manu Chhabra, M. Saeed Qureshi, Mekhola Mallik, Jason M. Ali, Ivonne Gamper, Ellen L. Moseley, Sarah Peacock, Vasilis Kosmoliaptsis, Martin J. Goddard, Michelle A. Linterman, Reza Motallebzadeh, Gavin J. Pettigrew
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Humoral alloimmunity is now recognized as a major determinant of transplant outcome. MHC glycoprotein is considered a typical T-dependent antigen, but the nature of the T cell alloresponse that underpins alloantibody generation remains poorly underst
Externí odkaz:
https://doaj.org/article/2ead543d0c1748e9bcdf4d6a176dd7b3
Augmentation of Recipient Adaptive Alloimmunity by Donor Passenger Lymphocytes within the Transplant
Autor:
Ines G. Harper, Jason M. Ali, Simon J.F. Harper, Elizabeth Wlodek, Jawaher Alsughayyir, Margaret C. Negus, M. Saeed Qureshi, Reza Motalleb-Zadeh, Kourosh Saeb-Parsy, Eleanor M. Bolton, J. Andrew Bradley, Menna R. Clatworthy, Thomas M. Conlon, Gavin J. Pettigrew
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1214-1227 (2016)
Chronic rejection of solid organ allografts remains the major cause of transplant failure. Donor-derived tissue-resident lymphocytes are transferred to the recipient during transplantation, but their impact on alloimmunity is unknown. Using mouse car
Externí odkaz:
https://doaj.org/article/07a9ed976d0c42a78866dd7854f9ab85
Autor:
Jason M. Ali, Margaret C. Negus, Thomas M. Conlon, Ines G. Harper, M. Saeed Qureshi, Reza Motallebzadeh, Richard Willis, Kourosh Saeb-Parsy, Eleanor M. Bolton, J. Andrew Bradley, Gavin J. Pettigrew
Publikováno v:
Cell Reports, Vol 14, Iss 5, Pp 1232-1245 (2016)
Summary: MHC alloantigen is recognized by two pathways: “directly,” intact on donor cells, or “indirectly,” as self-restricted allopeptide. The duration of each pathway, and its relative contribution to allograft vasculopathy, remain unclear.
Externí odkaz:
https://doaj.org/article/4d21d09f7ab64d809b676569f934b23c
Publikováno v:
J Thorac Dis
BACKGROUND: Significant bleeding following cardiac surgery is a recognised complication, associated with a requirement for re-exploration and blood transfusion, both associated with increased morbidity and early mortality. The aim of this study was t
Publikováno v:
The Annals of Thoracic Surgery. 111:1570-1577
Considerable mediastinal bleeding is a recognized complication after cardiac surgery and may require reexploration and blood product transfusion, both of which are associated with inferior clinical outcomes with greater morbidity and mortality. The a
Autor:
Yasir Abu-Omar, Jason M. Ali
Publikováno v:
J Thorac Dis