Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jason Lenox-Krug"'
Autor:
Mark N. Warden, Susan Searles Nielsen, Joel S. Perlmutter, Stephen M. Moerlein, Jason Lenox-Krug, Susan R. Criswell, Wendy W. Dlamini, Lianne Sheppard, Harvey Checkoway, Brad A. Racette
Publikováno v:
Toxicol Sci
The relationships between the neurotoxicant manganese (Mn), dopaminergic pathology, and parkinsonism remain unclear. Therefore, we used [11C](N-methyl)benperidol (NMB) positron emission tomography to investigate the associations between Mn exposure,
Autor:
Joel S. Perlmutter, Susan Searles Nielsen, Jason Lenox-Krug, Lianne Sheppard, Stephen M. Moerlein, Susan R. Criswell, Brad A. Racette, Mark N. Warden, Harvey Checkoway
Publikováno v:
J Occup Environ Med
OBJECTIVE: To understand the neurotoxic effects of manganese (Mn) exposure on monoaminergic function, utilizing [(11)C]dihydrotetrabenazine (DTBZ) positron emission tomography (PET) to measure vesicular monoamine transporter 2 (VMAT2). METHODS: Basal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d9c1f063fadc8705eec1e241906faa
https://europepmc.org/articles/PMC7786890/
https://europepmc.org/articles/PMC7786890/
Autor:
Brad A. Racette, Harvey Checkoway, Mark N. Warden, Susan Searles Nielsen, Susan R. Criswell, Jason Lenox-Krug, Sophia Racette, Lianne Sheppard, Hubert P. Flores
Objective T1-weighted brain magnetic resonance imaging (MRI) of the basal ganglia provides a noninvasive measure of manganese (Mn) exposure, and may also represent a biomarker for clinical neurotoxicity. Methods We acquired T1-weighted MRI scans in 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980945e6366b3f21e90625008b747bc6
https://europepmc.org/articles/PMC7098806/
https://europepmc.org/articles/PMC7098806/
Autor:
Joel S. Perlmutter, Brad A. Racette, Lianne Sheppard, Mark N. Warden, Susan Searles Nielsen, Stephen M. Moerlein, Jason Lenox-Krug, Harvey Checkoway, Susan R. Criswell
Publikováno v:
Neurology. 91(11)
ObjectiveTo investigate the associations between manganese (Mn) exposure, D2 dopamine receptors (D2Rs), and parkinsonism using [11C](N-methyl)benperidol (NMB) PET.MethodsWe used NMB PET to evaluate 50 workers with a range of Mn exposure: 22 Mn-expose