Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jason L. O'Loughlin"'
Autor:
Jason L O'Loughlin, Tyson P Eucker, Juan D Chavez, Derrick R Samuelson, Jason Neal-McKinney, Christopher R Gourley, James E Bruce, Michael E Konkel
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118533 (2015)
Campylobacter jejuni is a leading bacterial cause of human gastroenteritis. The goal of this study was to analyze the C. jejuni F38011 strain, recovered from an individual with severe enteritis, at a genomic and proteomic level to gain insight into m
Externí odkaz:
https://doaj.org/article/a75237a0a4114a1383968169d881bd2b
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39967 (2012)
Innate immune activation via Toll-like receptors (TLRs), although critical for host defense against infection, must be regulated to prevent sustained cell activation that can lead to cell death. Cells repeatedly stimulated with lipopolysaccharide (LP
Externí odkaz:
https://doaj.org/article/b6fabe1aa7df40ebb39943804053cdee
Autor:
Justin L Spinner, Keun Seok Seo, Jason L O'Loughlin, Jennifer A Cundiff, Scott A Minnich, Gregory A Bohach, Scott D Kobayashi
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9279 (2010)
BackgroundThe human innate immune system relies on the coordinated activity of macrophages and polymorphonuclear leukocytes (neutrophils or PMNs) for defense against bacterial pathogens. Yersinia spp. subvert the innate immune response to cause disea
Externí odkaz:
https://doaj.org/article/3f5147da69a249e9a95227c3368a268c
Autor:
Michael E. Konkel, Jason L. O’Loughlin, Derrick R. Samuelson, Charles L. Larson, Tyson P. Eucker
Publikováno v:
Emerging Microbes & Infections
Campylobacter jejuni is a gram-negative, curved and rod-shaped bacterium that causes human gastroenteritis. Acute disease is associated with C. jejuni invasion of the intestinal epithelium. Epithelial cells infected with C. jejuni strains containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6ce6ae14f52555bdfc3a07e6b422e7
https://doi.org/10.1038/emi.2013.65
https://doi.org/10.1038/emi.2013.65
Autor:
Jennifer B. Stone, Derrick R. Samuelson, Bryan A. White, Michael E. Konkel, Jeremy J. Lessmann, Jason L. O’Loughlin, Gary J. Haldorson, Andrea Braundmeier-Fleming, Tyson P. Eucker
Campylobacter jejuni is a leading cause of human foodborne gastroenteritis worldwide. The interactions between this pathogen and the intestinal microbiome within a host are of interest as endogenous intestinal microbiota mediates a form of resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c5ab84b03cd54027e3d6c93c26e284
https://europepmc.org/articles/PMC4551207/
https://europepmc.org/articles/PMC4551207/
Autor:
James E. Bruce, Michael E. Konkel, Derrick R. Samuelson, Jason L. O’Loughlin, Jason M. Neal-McKinney, Tyson P. Eucker, Juan D. Chavez, Christopher R. Gourley
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118533 (2015)
PLoS ONE
PLoS ONE
Campylobacter jejuni is a leading bacterial cause of human gastroenteritis. The goal of this study was to analyze the C. jejuni F38011 strain, recovered from an individual with severe enteritis, at a genomic and proteomic level to gain insight into m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcccd91b27cfc1760d7e2e010ff1574
http://europepmc.org/articles/PMC4335053?pdf=render
http://europepmc.org/articles/PMC4335053?pdf=render
Autor:
Scott A. Minnich, Carolyn J. Hovde, Darren R. Schnider, Seung Yong Lim, Scott S. Minnich, Claudia F. Deobald, Jason L. O'Loughlin, Austin K. Viall, Harold N. Rohde, Joon Bae Hong, Jong Wan Kim, Gregory A. Bohach, Joo Youn Park, B. Joseph Hinnebusch, Keun Seok Seo
A comprehensive Tn phoA mutant library was constructed in Yersinia pestis KIM6 to identify surface proteins involved in Y. pestis host cell invasion and bacterial virulence. Insertion site analysis of the library repeatedly identified a 9,042-bp chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694a799f20f1552023cde72cd329160c
https://europepmc.org/articles/PMC3457552/
https://europepmc.org/articles/PMC3457552/
Autor:
Jennifer A. Cundiff, Scott A. Minnich, Scott D. Kobayashi, Justin L. Spinner, Gregory A. Bohach, Keun Seok Seo, Jason L. O'Loughlin
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9279 (2010)
PLoS ONE
PLoS ONE
BackgroundThe human innate immune system relies on the coordinated activity of macrophages and polymorphonuclear leukocytes (neutrophils or PMNs) for defense against bacterial pathogens. Yersinia spp. subvert the innate immune response to cause disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8980921f02aec53ca99db6df64858a
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20174624/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20174624/?tool=EBI
Human polymorphonuclear leukocytes (PMNs, or neutrophils) are the most abundant innate immune cell and kill most invading bacteria through combined activities of reactive oxygen species (ROS) and antimicrobial granule constituents. Pathogens such asY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c13fdb1de72ee2e976ac0bbb77b895
https://europepmc.org/articles/PMC2812203/
https://europepmc.org/articles/PMC2812203/
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 6, p e39967 (2012)
PLoS ONE, Vol 7, Iss 6, p e39967 (2012)
Innate immune activation via Toll-like receptors (TLRs), although critical for host defense against infection, must be regulated to prevent sustained cell activation that can lead to cell death. Cells repeatedly stimulated with lipopolysaccharide (LP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899cd2a448195ee24aab7959853c86d4
https://doi.org/10.1371/journal.pone.0039967
https://doi.org/10.1371/journal.pone.0039967