Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jason L. Nathanson"'
Autor:
Matteo D'Antonio, Grace Woodruff, Jason L. Nathanson, Agnieszka D'Antonio-Chronowska, Angelo Arias, Hiroko Matsui, Roy Williams, Cheryl Herrera, Sol M. Reyna, Gene W. Yeo, Lawrence S.B. Goldstein, Athanasia D. Panopoulos, Kelly A. Frazer
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 1101-1111 (2017)
Summary: Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) offers the possibility of studying the molecular mechanisms underlying human diseases in cell types difficult to extract from living patients, such as neurons and cardiomy
Externí odkaz:
https://doaj.org/article/d69ba0728ffa406fb5c715d23e40fe06
Autor:
Sebastian Markmiller, Joshua L. Schwartz, David E. Hill, Gene W. Yeo, Archana Shankar, Jonathan C. Schmok, Gabriel A. Pratt, Duy B. Scaletta, Brian A. Yee, Stefan Aigner, Frederick E. Tan, Shashank Sathe, Jason L. Nathanson, Yuanchi Ha, En-Ching Luo
Publikováno v:
Nature structural & molecular biology, vol 27, iss 10
Nat Struct Mol Biol
Nat Struct Mol Biol
The molecular functions of the majority of RNA-binding proteins (RBPs) remain unclear, highlighting a major bottleneck to a full understanding of gene expression regulation. Here, we develop a plasmid resource of 690 human RBPs that we subject to luc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c24a6237dec4ffeb782ed4b0b5f261
https://escholarship.org/uc/item/5kd0v4kq
https://escholarship.org/uc/item/5kd0v4kq
Autor:
Angelo Arias, Agnieszka D'Antonio-Chronowska, Cheryl Herrera, Jason L. Nathanson, Hiroko Matsui, Grace Woodruff, Matteo D’Antonio, Kelly A. Frazer, Lawrence S.B. Goldstein, Athanasia D. Panopoulos, Gene W. Yeo, Sol M. Reyna, Roy Williams
Publikováno v:
Stem cell reports, vol 8, iss 4
Stem Cell Reports, Vol 8, Iss 4, Pp 1101-1111 (2017)
Stem Cell Reports
Stem Cell Reports, Vol 8, Iss 4, Pp 1101-1111 (2017)
Stem Cell Reports
Summary Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) offers the possibility of studying the molecular mechanisms underlying human diseases in cell types difficult to extract from living patients, such as neurons and cardiomyo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6434726e12de09b3097b00815783d7b
https://doi.org/10.1016/j.stemcr.2017.03.011
https://doi.org/10.1016/j.stemcr.2017.03.011
Autor:
Fred H. Gage, Susan M. Sunkin, Allan R. Jones, Changkyu Lee, Sheila Shapouri, Amy Bernard, Michael Hawrylycz, Rachel A. Dalley, Kimberly A. Smith, Jeremy A. Miller, Daniel Franjic, Ed S. Lein, Jeffrey Bennett, Jason L Nathanson, Nenad Sestan, Sungbo Shim, David G. Amaral
Publikováno v:
Development. 140:4633-4644
The neurogenic potential of the subgranular zone (SGZ) of the hippocampal dentate gyrus is likely to be regulated by molecular cues arising from its complex heterogeneous cellular environment. Through transcriptome analysis using laser microdissectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa1ab476ce007790162813ef225a37a
https://doi.org/10.1242/dev.097212
https://doi.org/10.1242/dev.097212
Autor:
Gene W. Yeo, Alysson R. Muotri, Keval N. Desai, Apuã C. M. Paquola, Matthew D. Weitzman, Fred H. Gage, Maria C. Marchetto, Ahmet M. Denli, Christopher Benner, Roberto H. Herai, Jason L. Nathanson, Iñigo Narvaiza, Thomas A. Lazzarini
Publikováno v:
Nature, vol 503, iss 7477
Identifying cellular and molecular differences between human and non-human primates (NHPs) is essential to the basic understanding of the evolution and diversity of our own species. Until now, preserved tissues have been the main source for most comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4995a2d14355d0ecf6e327738e6836a5
https://doi.org/10.1038/nature12686
https://doi.org/10.1038/nature12686
Autor:
Hilal Kazan, Anthony Q. Vu, Tiffany Y. Liang, Bernice Y. Yan, Gene W. Yeo, Quaid Morris, Jason L. Nathanson, Kasey R. Hutt, Shawn Hoon, Thomas J. Stark, Michael T. Lovci, Katannya Kapeli, Katlin B. Massirer, Stephanie C. Huelga, Melissa L. Wilbert, Stella X. Chen
Publikováno v:
Molecular Cell. 48(2):195-206
LIN28 is a conserved RNA-binding protein implicated in pluripotency, reprogramming, and oncogenesis. It was previously shown to act primarily by blocking let-7 microRNA (miRNA) biogenesis, but here we elucidate distinct roles of LIN28 regulation via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5fe229bc835a3d2ad651b10a80426e6
Publikováno v:
Neuroscience. 161:441-450
Despite increasingly widespread use of recombinant adeno-associated virus (AAV) and lentiviral (LV) vectors for transduction of neurons in a wide range of brain structures and species, the diversity of cell types within a given brain structure is rar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c58ca4657e24df018d572d1030dc0a
https://doi.org/10.1016/j.neuroscience.2009.03.032
https://doi.org/10.1016/j.neuroscience.2009.03.032
Publikováno v:
Gene Expression Patterns. 8:36-46
Erythrocyte tropomodulin (E-Tmod, Tmod1) is a tropomyosin-binding protein that caps the slow-growing end of actin filaments. In erythrocytes, it may favor the formation of short actin protofilaments needed for elastic cell deformation. Previously we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1309eeb00f3455724a4b3f006345270
https://doi.org/10.1016/j.modgep.2007.08.002
https://doi.org/10.1016/j.modgep.2007.08.002
Autor:
Christopher Vollmers, Satchidananda Panda, Jason L. Nathanson, Joseph R. Ecker, Robert J. Schmitz, Gene W. Yeo
In the mouse liver, circadian transcriptional rhythms are necessary for metabolic homeostasis. Whether dynamic epigenomic modifications are associated with transcript oscillations has not been systematically investigated. We found in addition to mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52c924f7f5b389285e05a0aaf0e2503
https://europepmc.org/articles/PMC3541940/
https://europepmc.org/articles/PMC3541940/
Autor:
Luciana Nogueira de Sousa Andrade, Alysson R. Muotri, Gene W. Yeo, Carlos Frederico Martins Menck, Jason L. Nathanson
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Cockayne syndrome (CS) is a human premature aging disorder associated with neurological and developmental abnormalities, caused by mutations mainly in the CS group B gene (ERCC6). At the molecular level, CS is characterized by a deficiency in the tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5581191a3f00b9c50de7f9c0a1c8e99
https://pubmed.ncbi.nlm.nih.gov/22661500
https://pubmed.ncbi.nlm.nih.gov/22661500