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of 6
pro vyhledávání: '"Jason Kin Wai Koo"'
Autor:
Yit Teng Hor, Dominic Chih-Cheng Voon, Jason Kin Wai Koo, Huajing Wang, Wen Min Lau, Hassan Ashktorab, Shing Leng Chan, Yoshiaki Ito
Publikováno v:
Cell Reports, Vol 8, Iss 1, Pp 50-58 (2014)
RUNX3 functions as a tumor suppressor in the gastric epithelium, where its inactivation is frequently observed during carcinogenesis. We identified IL23A as a RUNX3 target gene in gastric epithelial cells. This was confirmed in a series of in vitro a
Externí odkaz:
https://doaj.org/article/f145bc824b9940188673b68ea9c697b3
Autor:
Dominic Chih-Cheng Voon, Huajing Wang, Jason Kin Wai Koo, Juin Hsien Chai, Yit Teng Hor, Tuan Zea Tan, Yeh-Shiu Chu, Seiichi Mori, Yoshiaki Ito
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70427 (2013)
Recent studies have revealed that differentiated epithelial cells would acquire stem cell-like and tumorigenic properties following an Epithelial-Mesenchymal Transition (EMT). However, the signaling pathways that participate in this novel mechanism o
Externí odkaz:
https://doaj.org/article/02cb0950139e4fabaef59917a9bed864
Autor:
Dominic Chih-Cheng Voon, Shing Leng Chan, Yit Teng Hor, Yoshiaki Ito, Wen Min Lau, Hassan Ashktorab, Huajing Wang, Jason Kin Wai Koo
Publikováno v:
Cell reports
Cell Reports, Vol 8, Iss 1, Pp 50-58 (2014)
Cell Reports, Vol 8, Iss 1, Pp 50-58 (2014)
SUMMARY RUNX3 functions as a tumor suppressor in the gastric epithelium, where its inactivation is frequently observed during carcinogenesis. We identified IL23A as a RUNX3 target gene in gastric epithelial cells. This was confirmed in a series of in
Autor:
Seiichi Mori, Yeh Shiu Chu, Huajing Wang, Dominic Chih-Cheng Voon, Juin Hsien Chai, Yoshiaki Ito, Jason Kin Wai Koo, Tuan Zea Tan, Yit Teng Hor
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70427 (2013)
PLoS ONE
PLoS ONE
Recent studies have revealed that differentiated epithelial cells would acquire stem cell-like and tumorigenic properties following an Epithelial-Mesenchymal Transition (EMT). However, the signaling pathways that participate in this novel mechanism o
Autor:
Tu Anh Pham Nguyen, Jason Kin Wai Koo, Yit Teng Hor, Kosei Ito, Hiroshi Fukamachi, Yeh Shiu Chu, Yoshiaki Ito, Jean Paul Thiery, Huajing Wang, Dominic Chih-Cheng Voon, Shing Leng Chan
Publikováno v:
Stem cells (Dayton, Ohio). 30(10)
The transcription factor RUNX3 functions as a tumor suppressor in the gastrointestinal epithelium, where its loss is an early event in carcinogenesis. While RUNX3 acts concurrently as a mediator of TGF-β signaling and an antagonist of Wnt, the cellu
Autor:
Motomi Osato, Yoshiaki Ito, Lena Motoda, Hiroshi Fukamachi, Linda Shyue Huey Chuang, Cecilia Wei Lin Lee, Dominic Chih-Cheng Voon, Huajing Wang, Jason Kin Wai Koo, Manuel Salto-Tellez, Anthony C.B. Lim, Kosei Ito
Publikováno v:
Cancer cell. 14(3)
In intestinal epithelial cells, inactivation of APC, a key regulator of the Wnt pathway, activates beta-catenin to initiate tumorigenesis. However, other alterations may be involved in intestinal tumorigenesis. Here we found that RUNX3, a gastric tum