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pro vyhledávání: '"Jason Keng-Ying Tu"'
Autor:
Sanam Movassaghi, Jason Keng-Ying Tu, Betty Y. T. Lee, Tilo Söhnel, Christian G. Hartinger, Euphemia Leung, Stephen M. F. Jamieson, Muhammad Hanif, Hannah U. Holtkamp
Publikováno v:
Inorganic Chemistry. 57:8521-8529
RuII(η6-arene) compounds carrying bioactive flavonol ligands have shown promising anticancer activity against tumor cells via a multitargeting mode of action, i.e., through interaction with DNA and inhibition of topoisomerase IIα. By introducing a
Autor:
Jason Keng-Ying Tu, Bernhard K. Keppler, Christian G. Hartinger, Michaela Hejl, Wolfgang Kandioller, Michael A. Jakupec, Tilo Söhnel, Mario Kubanik
Publikováno v:
Metallodrugs. 1
3-Hydroxyflavones belong to the naturally occurring class of flavonoids and have been extensively studied with regard to medicinal application. Moreover, it has been demonstrated that these compounds act as bioactive chelates to the ruthenium(II)–a