Výsledky vyhledávání - "Jason K. W. Yap"

Akademický článek

Aberrant activation of the Hedgehog signalling pathway in squamous cell carcinoma of the vulva as a potential target for cancer therapy

Autor: Jason K. W. Yap, Khalil Uddin, Rachel Pounds, Danielle O’Neill, Sean Kehoe, Raji Ganesan, Christopher W. Dawson

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)

Abstract In a previous study, we showed that the Hedgehog (Hh) signalling pathway is aberrantly activated in vulval squamous cell carcinoma (VSCC). In this study, we further validated our findings on a prospective cohort of primary VSCC cases, where

Externí odkaz: https://doaj.org/article/05f946613f6a40b3894bfa1218318429

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

The Major Constituent of Green Tea, Epigallocatechin-3-Gallate (EGCG), Inhibits the Growth of HPV18-Infected Keratinocytes by Stimulating Proteasomal Turnover of the E6 and E7 Oncoproteins

Autor: Jason K. W. Yap, Sean T. Kehoe, Ciaran B. J. Woodman, Christopher W. Dawson

Publikováno v: Pathogens, Vol 10, Iss 4, p 459 (2021)

Epigallocatechin-3-gallate (EGCG), the primary bioactive polyphenol in green tea, has been shown to inhibit the growth of human papilloma virus (HPV)-transformed keratinocytes. Here, we set out to examine the consequences of EGCG treatment on the gro

Externí odkaz: https://doaj.org/article/df76d9deb341473095fb378fbf7ac741

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání