Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jason K Yokoyama"'
Autor:
Michael C Jensen, Katherine J Brempelis, Courtney M Cowan, Shannon A Kreuser, Kevin P Labadie, Brooke M Prieskorn, Nicole A P Lieberman, Chibawanye I Ene, Kara W Moyes, Harrison Chinn, Kole R DeGolier, Lisa R Matsumoto, Sara K Daniel, Jason K Yokoyama, Amira D Davis, Virginia J Hoglund, Kimberly S Smythe, Stephanie D Balcaitis, Richard G Ellenbogen, Jean S Campbell, Eric C Holland, Courtney A Crane
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Though currently approved immunotherapies, including chimeric antigen receptor T cells and checkpoint blockade antibodies, have been successfully used to treat hematological and some solid tumor cancers, many solid tumors remain resistant
Externí odkaz:
https://doaj.org/article/c3322864d2c54a13b3b2a3dea90a8cdb
Autor:
Michael C Jensen, Katherine J Brempelis, Courtney M Cowan, Shannon A Kreuser, Kevin P Labadie, Brooke M Prieskorn, Nicole A P Lieberman, Chibawanye I Ene, Kara W Moyes, Harrison Chinn, Kole R DeGolier, Lisa R Matsumoto, Sara K Daniel, Jason K Yokoyama, Amira D Davis, Virginia J Hoglund, Kimberly S Smythe, Stephanie D Balcaitis, Richard G Ellenbogen, Jean S Campbell, Eric C Holland, Courtney A Crane
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Externí odkaz:
https://doaj.org/article/6661308b20f8413cb4e189e81af730a6
Autor:
Julie R. Park, Michael C. Jensen, Rebecca A. Gardner, Juliane Gust, Navin Pinto, Amanda G. Paulovich, Lei Zhao, Jeffrey R. Whiteaker, Evan W. Newell, Tony Chour, Rimas J. Orentas, Jason N. Wright, Francisco A. Perez, Bonnie L. Cole, Sarah E.S. Leary, Erin E. Crotty, Jessica B. Foster, Matthew D. Dun, Michael E. Berens, Jeffrey G. Ojemann, Amy Lee, Jason S. Hauptman, Samuel R. Browd, Catherine M. Albert, Stephanie D. Rawlings-Rhea, Carrie Myers, Matthew C. Biery, Michael Meechan, Aquene N. Reid, Ryan W. Koning, Blake A. Baxter, Adam J. Johnson, Jason K. Yokoyama, Joshua A. Gustafson, Christopher Brown, Kristy Seidel, Wenjun Huang, Ashley L. Wilson, Nicholas A. Vitanza
Diffuse intrinsic pontine glioma (DIPG) remains a fatal brainstem tumor demanding innovative therapies. As B7-H3 (CD276) is expressed on central nervous system (CNS) tumors, we designed B7-H3–specific chimeric antigen receptor (CAR) T cells, confir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4067a486b2678d4a886a294e60b09ff9
https://doi.org/10.1158/2159-8290.c.6549724.v1
https://doi.org/10.1158/2159-8290.c.6549724.v1
Autor:
Julie R. Park, Michael C. Jensen, Rebecca A. Gardner, Juliane Gust, Navin Pinto, Amanda G. Paulovich, Lei Zhao, Jeffrey R. Whiteaker, Evan W. Newell, Tony Chour, Rimas J. Orentas, Jason N. Wright, Francisco A. Perez, Bonnie L. Cole, Sarah E.S. Leary, Erin E. Crotty, Jessica B. Foster, Matthew D. Dun, Michael E. Berens, Jeffrey G. Ojemann, Amy Lee, Jason S. Hauptman, Samuel R. Browd, Catherine M. Albert, Stephanie D. Rawlings-Rhea, Carrie Myers, Matthew C. Biery, Michael Meechan, Aquene N. Reid, Ryan W. Koning, Blake A. Baxter, Adam J. Johnson, Jason K. Yokoyama, Joshua A. Gustafson, Christopher Brown, Kristy Seidel, Wenjun Huang, Ashley L. Wilson, Nicholas A. Vitanza
Supplementary Data from Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7f1c03edf81eee74a2a24740e9108e
https://doi.org/10.1158/2159-8290.22541686
https://doi.org/10.1158/2159-8290.22541686
Autor:
Catherine M. Albert, Cindy A. Chang, Stephanie Rawlings-Rhea, Jason N. Wright, Kristy Seidel, Navin Pinto, Juliane Gust, Adam Johnson, Rebecca Gardner, Christopher Brown, Rimas J. Orentas, Michael C. Jensen, Wenjun Huang, Julie R. Park, Ashley Wilson, Michael L. Baldwin, Laura S. Finn, Nicholas A Vitanza, Jeffrey G. Ojemann, Annette Künkele, Jason K. Yokoyama
Publikováno v:
Nature Medicine. 27:1544-1552
Locoregional delivery of chimeric antigen receptor (CAR) T cells has resulted in objective responses in adults with glioblastoma, but the feasibility and tolerability of this approach is yet to be evaluated for pediatric central nervous system (CNS)
Autor:
Nicholas A. Vitanza, Ashley L. Wilson, Wenjun Huang, Kristy Seidel, Christopher Brown, Joshua A. Gustafson, Jason K. Yokoyama, Adam J. Johnson, Blake A. Baxter, Ryan W. Koning, Aquene N. Reid, Michael Meechan, Matthew C. Biery, Carrie Myers, Stephanie D. Rawlings-Rhea, Catherine M. Albert, Samuel R. Browd, Jason S. Hauptman, Amy Lee, Jeffrey G. Ojemann, Michael E. Berens, Matthew D. Dun, Jessica B. Foster, Erin E. Crotty, Sarah E.S. Leary, Bonnie L. Cole, Francisco A. Perez, Jason N. Wright, Rimas J. Orentas, Tony Chour, Evan W. Newell, Jeffrey R. Whiteaker, Lei Zhao, Amanda G. Paulovich, Navin Pinto, Juliane Gust, Rebecca A. Gardner, Michael C. Jensen, Julie R. Park
Publikováno v:
Cancer discovery. 13(1)
Diffuse intrinsic pontine glioma (DIPG) remains a fatal brainstem tumor demanding innovative therapies. As B7-H3 (CD276) is expressed on central nervous system (CNS) tumors, we designed B7-H3–specific chimeric antigen receptor (CAR) T cells, confir
Autor:
Nicholas A, Vitanza, Adam J, Johnson, Ashley L, Wilson, Christopher, Brown, Jason K, Yokoyama, Annette, Künkele, Cindy A, Chang, Stephanie, Rawlings-Rhea, Wenjun, Huang, Kristy, Seidel, Catherine M, Albert, Navin, Pinto, Juliane, Gust, Laura S, Finn, Jeffrey G, Ojemann, Jason, Wright, Rimas J, Orentas, Michael, Baldwin, Rebecca A, Gardner, Michael C, Jensen, Julie R, Park
Publikováno v:
Nature medicine. 27(9)
Locoregional delivery of chimeric antigen receptor (CAR) T cells has resulted in objective responses in adults with glioblastoma, but the feasibility and tolerability of this approach is yet to be evaluated for pediatric central nervous system (CNS)
Autor:
Shannon A Kreuser, Venu G. Pillarisetty, Robert H. Pierce, Nicole A P Lieberman, Courtney A. Crane, Michael C. Jensen, Stephanie Balcaitis, Kimberly S. Smythe, Lisa R Matsumoto, Kole DeGolier, Virginia Hoglund, Katherine J. Brempelis, Chibawanye I. Ene, Amira Davis, Kevin P. Labadie, Harrison Chinn, Richard G. Ellenbogen, Eric C. Holland, Jason K. Yokoyama, Brooke M Prieskorn, Kara White Moyes, Sara K. Daniel, Courtney M Cowan, Jean S. Campbell
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
BackgroundThough currently approved immunotherapies, including chimeric antigen receptor T cells and checkpoint blockade antibodies, have been successfully used to treat hematological and some solid tumor cancers, many solid tumors remain resistant t
Autor:
Jason K. Yokoyama, Blake Baxter, Wenjun Huang, Rebecca Gardner, Stephanie Rhea, Corinne Summers, Julie R. Park, Michael C. Jensen, Colleen Annesley, Ashley Wilson, Rimas J. Orentas
Publikováno v:
Blood. 138:403-403
Background: CD19 targeting chimeric antigen receptor (CAR) T cells have induced unprecedented remission rates in high-risk precursor B Acute Lymphoblastic Leukemia (ALL); however recurrent disease with CD19 antigen escape variants is not uncommon. Th
Autor:
Jule Gust, Amanda G. Paulovich, Julie Park, Adam Johnson, Michael E. Berens, Rebecca Gardner, Catherine M. Albert, Nicholas Vitanza, Wenjun Huang, Rimas J. Orentas, Michael C. Jensen, Navin Pinto, Jessica B. Foster, Ashley Wilson, Jason K. Yokoyama
Publikováno v:
Neuro Oncol
Following preclinical optimization of B7-H3-specific CAR T cells against pediatric brain tumor models, we opened BrainChild-03 (NCT04185038), a phase 1 clinical trial of repeatedly dosed, outpatient, locoregional B7-H3-specific CAR T cells for childr