Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jason J. Rodriguez"'
Autor:
Jason J. Rodriguez, Stephen P. Goff
Publikováno v:
Journal of Virology. 84:2556-2562
Xenotropic murine leukemia virus-related virus (XMRV) is a novel human gammaretrovirus discovered in association with human prostate tumors. XMRV was first identified in prostate stromal cells surrounding the tumors of patients carrying a mutation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8fdbffe6b9b270311c94eadea588760
https://doi.org/10.1128/jvi.01969-09
https://doi.org/10.1128/jvi.01969-09
Publikováno v:
Journal of Virology. 82:6259-6271
Emerging viruses in the paramyxovirus genus Henipavirus evade host antiviral responses via protein interactions between the viral V and W proteins and cellular STAT1 and STAT2 and the cytosolic RNA sensor MDA5. Polo-like kinase (PLK1) is identified a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e039149ac279753609badc9a482ef615
https://doi.org/10.1128/jvi.00409-08
https://doi.org/10.1128/jvi.00409-08
Autor:
Curt M. Horvath, Jason J. Rodriguez
Publikováno v:
Viral Immunology. 17:210-219
Interferon (IFN) can activate Signal Transducer and Activator of Transcription (STAT) proteins to establish a cellular antiviral response and inhibit virus replication. Many viruses have evolved strategies to inhibit this antiviral mechanism, but par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e7d62810f602a62a16ecb377e4cbca
https://doi.org/10.1089/0882824041310568
https://doi.org/10.1089/0882824041310568
Publikováno v:
Journal of Virology. 78:5358-5367
The V proteins of Nipah virus and Hendra virus have been demonstrated to bind to cellular STAT1 and STAT2 proteins to form high-molecular-weight complexes that inhibit interferon (IFN)-induced antiviral transcription by preventing STAT nuclear accumu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2359752f812e82d67a4f7f2804f491
https://doi.org/10.1128/jvi.78.10.5358-5367.2004
https://doi.org/10.1128/jvi.78.10.5358-5367.2004
STAT Protein Interference and Suppression of Cytokine Signal Transduction by Measles Virus V Protein
Autor:
Jason J. Rodriguez, Heidi Palosaari, Curt M. Horvath, Jean Patrick Parisien, Christina M. Ulane
Publikováno v:
Journal of Virology. 77:7635-7644
Measles virus, a paramyxovirus of the Morbillivirus genus, is responsible for an acute childhood illness that infects over 40 million people and leads to the deaths of more than 1 million people annually (C. J. Murray and A. D. Lopez, Lancet 349:1269
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ca1eb2e5a8470b6282aa4337b755dd
https://doi.org/10.1128/jvi.77.13.7635-7644.2003
https://doi.org/10.1128/jvi.77.13.7635-7644.2003
Publikováno v:
Journal of Virology. 76:11476-11483
Interferons (IFNs) are the primary innate antiviral cytokines in mammalian cells and also regulate aspects of the adaptive immune response (3, 5, 27). Both IFN-α/β and IFN-γ can induce an antiviral state in cells as an end point of signal transduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ab98c08aecf9a5b4fd485c8c520e5a
https://doi.org/10.1128/jvi.76.22.11476-11483.2002
https://doi.org/10.1128/jvi.76.22.11476-11483.2002
Publikováno v:
Journal of Virology. 76:4190-4198
The alpha/beta interferon (IFN-α/β)-induced STAT signal transduction pathway leading to activation of the ISGF3 transcription complex and subsequent antiviral responses is the target of viral pathogenesis strategies. Members of the Rubulavirus genu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70188b3558825a467b1882d5e3a5299f
https://doi.org/10.1128/jvi.76.9.4190-4198.2002
https://doi.org/10.1128/jvi.76.9.4190-4198.2002
Autor:
Curt M. Horvath, Jason J. Rodriguez, Robert D. Wojahn, Akihiko Komuro, Glen N. Barber, Aparna Ramachandran, Jean Patrick Parisien, Darja Bamming
Detection of pathogens by the mammalian innate immune system is mediated by pattern recognition receptors. For viruses, nucleic acids are often the trigger for innate responses that culminate in antiviral gene expression, including the production of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44766c456765cb256f6dd8842bd44cab
https://europepmc.org/articles/PMC2704796/
https://europepmc.org/articles/PMC2704796/
The V protein of the recently emerged paramyxovirus, Nipah virus, has been shown to inhibit interferon (IFN) signal transduction through cytoplasmic sequestration of cellular STAT1 and STAT2 in high-molecular-weight complexes. Here we demonstrate tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d8e281e1381809470d15e46d6d5ca4
https://europepmc.org/articles/PMC296100/
https://europepmc.org/articles/PMC296100/
Publikováno v:
Journal of virology. 77(11)
Mumps virus is a common infectious agent of humans, causing parotitis, meningitis, encephalitis, and orchitis. Like other paramyxoviruses in the genusRubulavirus, mumps virus catalyzes the proteasomal degradation of cellular STAT1 protein, a means fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f0fcb85e0ced53355b982711c8ff60
https://pubmed.ncbi.nlm.nih.gov/12743296
https://pubmed.ncbi.nlm.nih.gov/12743296