Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jason J. Otterstrom"'
Publikováno v:
SLAS Technology, Vol 27, Iss 2, Pp 109-120 (2022)
Fundamental life science and pharmaceutical research are continually striving to provide physiologically relevant context for their biological studies. Zebrafish present an opportunity for high-content screening (HCS) to bring a true in vivo model sy
Externí odkaz:
https://doaj.org/article/7ad7ff4004eb4101a5f53a3af33caaab
Autor:
Daniel Rodriguez, Chi-Li Chiu, Jason J. Otterstrom, Samuel Ojosnegros, Stephen Mieruszynski, Scott E. Fraser, Elena Martínez, Verónica Hortigüela, Enara Larrañaga, Melike Lakadamyali, Anna Seriola, Angel Raya, Francesco Cutrale
Publikováno v:
Nature Protocols
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Protein dimerization and oligomerization are essential to most cellular functions, yet measurement of the size of these oligomers in live cells, especially when their size changes over time and space, remains a challenge. A commonly used approach for
Autor:
Boerries Brandenburg, Wouter Koudstaal, Jaap Goudsmit, Vincent Klaren, Chan Tang, Miriam V Bujny, Hans J W M Korse, Ted Kwaks, Jason J Otterstrom, Jarek Juraszek, Antoine M van Oijen, Ronald Vogels, Robert H E Friesen
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80034 (2013)
Human monoclonal antibodies have been identified which neutralize broad spectra of influenza A or B viruses. Here, we dissect the mechanisms by which such antibodies interfere with infectivity. We distinguish four mechanisms that link the conserved h
Externí odkaz:
https://doaj.org/article/94c3128c61834b27bb660217681e881d
Chromatin organization plays an important role in regulating gene expression. Previously, we showed that chromatin is organized in the form of nucleosome groups or clutches. The size and nucleosome packing density of clutches decreased in hyperacetyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff93ab7d3fc603251700716c1f9724a
https://doi.org/10.1101/470823
https://doi.org/10.1101/470823
Autor:
J. S. Borbely, Jason J. Otterstrom, Nitin Mohan, Don C. Lamb, Melike Lakadamyali, Ángel Sandoval Álvarez, Ione Verdeny-Vilanova, Fabian Wehnekamp
Publikováno v:
Journal of Cell Science
Vesicle transport is regulated at multiple levels, including regulation by scaffolding proteins and the cytoskeleton. This tight regulation is essential, since slowing or stoppage of transport can cause accumulation of obstacles and has been linked t
Autor:
Scott E. Fraser, Elena Martínez, Verónica Hortigüela, Carolina Tarantino, Stephen Mieruszynski, Francesco Cutrale, Daniel Rodriguez, Anna Seriola, Chi-Li Chiu, Jason J. Otterstrom, Samuel Ojosnegros, Melike Lakadamyali, Angel Raya
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Proceedings of the National Academy of Sciences
Recercat. Dipósit de la Recerca de Catalunya
instname
Universidad de Barcelona
Proceedings of the National Academy of Sciences
Recercat. Dipósit de la Recerca de Catalunya
instname
Eph receptor signaling plays key roles in vertebrate tissue boundary formation, axonal pathfinding, and stem cell regeneration by steering cells to positions defined by its ligand ephrin. Some of the key events in Eph-ephrin signaling are understood:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2839a18a09f0ee19f2a1afb46909a929
http://hdl.handle.net/2445/118589
http://hdl.handle.net/2445/118589
Publikováno v:
Biochemistry, 52(10), 1654-1668. AMER CHEMICAL SOC
Biochemistry
Biochemistry
Protein-mediated fusion between phospholipid bilayers is a fundamental and necessary mechanism for many cellular processes. The short-lived nature of the intermediate states visited during fusion makes it challenging to capture precise kinetic inform
Autor:
Don C. Lamb, Nitin Mohan, Joe Borbely, Melike Lakadamyali, Fabian Wehnekamp, Ángel Sandoval Álvarez, Ione Verdeny Vilanova, Jason J. Otterstrom
Publikováno v:
Biophysical Journal. 110(3)
Motor-driven cargo transport helps deliver several types of vesicles to the proper location of function. Motor proteins, such as dynein and kinesin, move vesicles through the complex 3D microtubule network. Motors encounter different roadblocks on th
Publikováno v:
SPIE Proceedings.
Super-resolution microscopy has revolutionized fluorescence imaging providing access to length scales that are much below the diffraction limit. The super-resolution methods have the potential for novel discoveries in biology. However, certain techni
Publikováno v:
Journal of Experimental Biology. 205:1755-1763
SUMMARY `Forehead to forehead I meet thee, this third time, Moby Dick!' [Ahab (Melville, 1851)] Herman Melville's fictional portrayal of the sinking of the Pequodwas inspired by instances in which large sperm whales sank whaling ships by ramming the