Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jason J. Kowal"'
Autor:
Ian W. Davies, Michael Palucki, Eugenia Njolito, Jason J. Kowal, Wenjie Li, Jonathan D. Rosen, Jenny M. Baxter, Jacob M. Janey, Rick Sidler, Orella Charles J
Publikováno v:
The Journal of Organic Chemistry. 73:3212-3217
An expedient, five step synthesis of caprolactam 1 is reported starting from natural L-homoserine. The key step is a chemoselective reductive cyclization of alpha,beta-unsaturated nitrile 10 mediated by Raney-Co type metals. This hydrogenation is ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41dcfc5d49e24b2d724c04e750c9f38e
https://doi.org/10.1021/jo8000996
https://doi.org/10.1021/jo8000996
Autor:
Dongwei Cai, Robert D. Larsen, David L. Hughes, Jason J. Kowal, Paul J. Reider, Michel Journet
Publikováno v:
Organic Process Research & Development. 9:490-498
A highly efficient synthesis of the substance P antagonist 1 is reported starting from the optically pure morpholine acetal derivative 2. The 5-dimethylaminomethyl-1,2,3-triazole moiety is elaborated via a 1,3-dipolar cycloaddition between an activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::955e83732e0df5d2ed2ecfb9665dc868
https://doi.org/10.1021/op050019s
https://doi.org/10.1021/op050019s
Autor:
Paul J. Reider, Jason J. Kowal, Dongwei Cai, Sandra Lee, Kevin R. Campos, Robert D. Larsen, Michel Journet
Publikováno v:
Tetrahedron Letters. 43:6957-6959
A general method for the monoalkylation of (+)-nopinone was developed for a variety of carbon and heteroatom electrophiles to afford the kinetically controlled product 2 with high diastereoselectivity (98% d.e.) and excellent yield (75–90%).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97cf8ccc1d2ab482d5871a7325529865
https://doi.org/10.1016/s0040-4039(02)01589-7
https://doi.org/10.1016/s0040-4039(02)01589-7
Autor:
Michel Journet, Robert D. Larsen, Kevin R. Campos, Jason J. Kowal, Dongwei Cai, Paul J. Reider
Publikováno v:
ChemInform. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6d06af758e7c141a5d18241c0d1ddf9
https://doi.org/10.1002/chin.200138084
https://doi.org/10.1002/chin.200138084
Publikováno v:
ChemInform. 33
Synthesis of variously 5-substituted-4-carbaldehyde-1,2,3-triazole derivatives 2 was accomplished by reacting sodium azide with α,β-acetylenic aldehydes 1 in DMSO at room temperature. Therefore, the reaction remains basic avoiding the generation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c59a35c033b2a9a8f5dc4fcd5c5543e5
https://doi.org/10.1002/chin.200211114
https://doi.org/10.1002/chin.200211114
Autor:
Sandra Lee, Kevin R. Campos, Jason J. Kowal, Robert D. Larsen, Dongwei Cai, Paul J. Reider, Michel Journet
Publikováno v:
ChemInform. 33
A general method for the monoalkylation of (+)-nopinone was developed for a variety of carbon and heteroatom electrophiles to afford the kinetically controlled product 2 with high diastereoselectivity (98% d.e.) and excellent yield (75–90%).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac83c652b4327e3b89a82523f71f4642
https://doi.org/10.1002/chin.200251182
https://doi.org/10.1002/chin.200251182
Controlled semihydrogenation of aminoalkynes using ethylenediamine as a poison of Lindlar's catalyst
Autor:
Jason J. Kowal, Robert D. Larsen, Kevin R. Campos, Dongwei Cai, Michel Journet, Paul J. Reider
Publikováno v:
The Journal of organic chemistry. 66(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae9ca9535aa14f7e96c8eb75790e1cb
https://pubmed.ncbi.nlm.nih.gov/11348162
https://pubmed.ncbi.nlm.nih.gov/11348162
Publikováno v:
Tetrahedron Letters. 42:9117-9118
Synthesis of variously 5-substituted-4-carbaldehyde-1,2,3-triazole derivatives 2 was accomplished by reacting sodium azide with α,β-acetylenic aldehydes 1 in DMSO at room temperature. Therefore, the reaction remains basic avoiding the generation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12d7cecb70f19fd9f00c4e4ecc7f9eea
https://doi.org/10.1016/s0040-4039(01)01923-2
https://doi.org/10.1016/s0040-4039(01)01923-2