Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jason J Siu"'
Autor:
William W Hwang, Ryan D Salinas, Jason J Siu, Kevin W Kelley, Ryan N Delgado, Mercedes F Paredes, Arturo Alvarez-Buylla, Michael C Oldham, Daniel A Lim
Publikováno v:
eLife, Vol 3 (2014)
The epigenetic mechanisms that enable specialized astrocytes to retain neurogenic competence throughout adult life are still poorly understood. Here we show that astrocytes that serve as neural stem cells (NSCs) in the adult mouse subventricular zone
Externí odkaz:
https://doaj.org/article/cb1ed4213f4c459aa9c851f670048417
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 7, Iss C, Pp 83-95 (2017)
Mutations in the melanocortin-4-receptor (MC4R) comprise the most common monogenic form of severe early-onset obesity, and conventional treatments are either ineffective long-term or contraindicated. Immediately downstream of MC4R—in the pathway fo
Externí odkaz:
https://doaj.org/article/fda2f35af3d741aaa5a014f371b0b9bb
Publikováno v:
Neuroscience
The administration of exogenous insulin into the hippocampus has the potential to enhance cognitive function and exert other beneficial effects. Elucidating the neurobiological substrates of insulin action and its underlying physiological mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a081313f4430b76b6dd88fe6672c446f
https://doi.org/10.1016/j.neuroscience.2019.05.033
https://doi.org/10.1016/j.neuroscience.2019.05.033
Autor:
Jason J Siu, David S. Shin, Eric J. Monroe, Jeffrey Forris Beecham Chick, Frederic Bertino, Claudia C Tenen
Publikováno v:
Journal of vascular and interventional radiology : JVIR. 32(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4159572c4969a109583133e55c6762
https://pubmed.ncbi.nlm.nih.gov/34062273
https://pubmed.ncbi.nlm.nih.gov/34062273
Autor:
Kris R. Jatana, Jason J. Siu, Nina Hill, Suzanne Reed, Tendy Chiang, Sarah M. Chen, Terri Guinipero, Dustin A. Silverman
Publikováno v:
International journal of pediatric otorhinolaryngology. 122
Myeloid sarcoma (MS) is an extramedullary collection of immature myeloid cells that can commonly occur with acute myeloid leukemia (AML). While head and neck presentations are not unheard of, there have been few published pediatric cases of external
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc07f6fa8440957d9e3f895efb557792
https://pubmed.ncbi.nlm.nih.gov/31005747
https://pubmed.ncbi.nlm.nih.gov/31005747
Publikováno v:
Aging Cell
The aging process and age‐related diseases all involve perturbed energy adaption and impaired ability to cope with adversity. Brain‐derived neurotrophic factor (BDNF) in the hypothalamus plays important role in regulation of energy balance. Our p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4dda179f0171a7a90586b337b3e216
http://europepmc.org/articles/PMC6413658
http://europepmc.org/articles/PMC6413658
Publikováno v:
Psychoneuroendocrinology
BTBR T + Itpr3tf/J (BTBR) mice are an Autism Spectrum Disorder (ASD)-like model that exhibit behavioral and physiological deficits similar to those observed in patients with ASD. While behavioral therapy is a first line of treatment in ASD patients,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859c223dcc3f8fd595d2e6b4bda28eb4
https://doi.org/10.1016/j.psyneuen.2019.104476
https://doi.org/10.1016/j.psyneuen.2019.104476
Autor:
Siu, Jason J., Siu
Gene therapy refers to the delivery of a genetic payload to a specific tissue in order to ideally mitigate disease. Popularized in the 1980s, there was heavy optimism that viruses would deliver functional genetic elements into patients to cure their
Autor:
Nicholas J. Queen, Run Xiao, Seemaab Ali, Ryan T. Judd, Ryan K. Wilkins, Kyle J. Widstrom, Stephen M. Bergin, Jason J. Siu, Wei Huang, Lei Cao, Xianglan Liu, Michael A. Caligiuri, Anthony Mansour
Publikováno v:
Brain, behavior, and immunity. 75
Environmental and social factors have profound impacts on immune homeostasis. Our work on environmental enrichment (EE) has revealed a novel anti-obesity and anticancer phenotype associated with enhanced activity of CD8+ cytotoxic T lymphocytes in se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b1c8121063215dca24b71bcbc7b925
https://pubmed.ncbi.nlm.nih.gov/30287389
https://pubmed.ncbi.nlm.nih.gov/30287389
Autor:
Sung Hak Kim, Ichiro Nakano, Erik P. Sulman, David Taylor, Jason J. Siu, Chunyu Gu, Krishna P.L. Bhat, Anna Elisabetta Salcini, Toshia R. Myers, Ravesanker Ezhilarasan, Jeongwu Lee, Mutsuko Minata, Mariko Nakano-Okuno, Kaushal Joshi
Publikováno v:
Stem Cell Reports, Vol 4, Iss 2, Pp 226-238 (2015)
Stem Cell Reports
Stem Cell Reports
Summary Glioblastoma (GBM)-derived tumorigenic stem-like cells (GSCs) may play a key role in therapy resistance. Previously, we reported that the mitotic kinase MELK binds and phosphorylates the oncogenic transcription factor FOXM1 in GSCs. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247d8ed3d459130d8a63785302549f39
https://doi.org/10.1016/j.stemcr.2014.12.006
https://doi.org/10.1016/j.stemcr.2014.12.006