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Autor:
Charles R. Mackay, Nancy Ruffing, Greg LaRosa, Howard H. Chen, Nasim Kassam, Heidi Heath, Michel Samson, Lijun Wu, Marc Parmentier, John P. Moore, Jason Humblias, Cynthia J. Gordon
Publikováno v:
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The Journal of Experimental Medicine
The Journal of Experimental Medicine
CCR5 is a chemokine receptor expressed by T cells and macrophages, which also functions as the principal coreceptor for macrophage (M)-tropic strains of HIV-1. To understand the molecular basis of the binding of chemokines and HIV-1 to CCR5, we devel