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pro vyhledávání: '"Jason Heale"'
Autor:
Alison E. M. Vickers, Jason Heale, Meg Ramos, Mike Bieraugel, Julia E Herrmann, Robyn L. Fisher
Publikováno v:
Toxicology and Applied Pharmacology. 274:302-312
Human response to isoproterenol induced cardiac injury was evaluated by gene and protein pathway changes in human heart slices, and compared to rat heart slices and rat heart in vivo. Isoproterenol (10 and 100μM) altered human and rat heart slice ma
Autor:
Josh M. Rowe, Jason Heale, Alison E. M. Vickers, John R. Sinclair, Stephen Morris, Robyn L. Fisher
Publikováno v:
Toxicology and Applied Pharmacology. 260:81-88
Drug induced thyroid effects were evaluated in organotypic models utilizing either a rat thyroid lobe or human thyroid slices to compare rodent and human response. An inhibition of thyroid peroxidase (TPO) function led to a perturbation in the expres